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Found 20 with Last Name = 'bergstrom' and Initial = 'de'
TargetThymidylate synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50000965(CHEMBL3228982)
Affinity DataKi:  8.60E+3nMAssay Description:Competitive inhibition of thymidylate synthetase (unknown origin) in presence of 5,10-methylenetetrahydrofolateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50002692((AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-...)
Affinity DataIC50:  40nMAssay Description:Concentration required to inhibit HIV reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50132287(1-((2R,4S,5R)-4-fluoro-5-(hydroxymethyl)tetrahydro...)
Affinity DataIC50: <50nMAssay Description:Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50018445(1-((2R,5S)-5-(hydroxymethyl)-tetrahydrofuran-2-yl)...)
Affinity DataIC50: <50nMAssay Description:Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Mus musculus)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511189(CHEMBL4571556)
Affinity DataIC50:  455nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Mus musculus)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511187(CHEMBL4542067)
Affinity DataIC50:  599nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Mus musculus)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511190(CHEMBL4592202)
Affinity DataIC50:  1.14E+3nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Mus musculus)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511191(CHEMBL4467543)
Affinity DataIC50:  1.42E+3nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Mus musculus)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511179(CHEMBL4453049)
Affinity DataIC50:  1.55E+3nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Mus musculus)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511186(CHEMBL4553079)
Affinity DataIC50:  2.16E+3nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Mus musculus)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511181(CHEMBL4464544)
Affinity DataIC50:  2.31E+3nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Mus musculus)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511182(CHEMBL4576109)
Affinity DataIC50:  2.54E+3nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Mus musculus)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511180(CHEMBL4548912)
Affinity DataIC50:  2.89E+3nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Mus musculus)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511192(CHEMBL4578086)
Affinity DataIC50:  4.69E+3nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Mus musculus)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511184(CHEMBL4518997)
Affinity DataIC50:  7.43E+3nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50004773(1-(4,4-Difluoro-5-hydroxymethyl-tetrahydro-furan-2...)
Affinity DataIC50:  8.80E+3nMAssay Description:Concentration required to inhibit HIV reverse transcriptaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Mus musculus)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511183(CHEMBL4465979)
Affinity DataIC50:  1.17E+4nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Mus musculus)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511185(CHEMBL4446603)
Affinity DataIC50:  1.18E+4nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Mus musculus)
Weill Cornell Medicine

Curated by ChEMBL
LigandPNGBDBM50511188(CHEMBL4461928)
Affinity DataIC50:  1.75E+4nMAssay Description:Inhibition of mouse MCP6 pre-incubated for 3 hrs before N-tert-butoxycarbonyl-Gln-Ala-Arg-AMC substrate addition and measured every 30 secs for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50000965(CHEMBL3228982)
Affinity DataKd:  2.50E+4nMAssay Description:Binding affinity to thymidylate synthetase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed