TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research and Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research and Development
Curated by ChEMBL
Affinity DataKi: 58nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research and Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research and Development
Curated by ChEMBL
Affinity DataKi: 62nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research and Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research and Development
Curated by ChEMBL
Affinity DataKi: 720nMAssay Description:Inhibition of 125[I] Fibrinogen binding to isolated purified human fibrinogen receptorMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research and Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research and Development
Curated by ChEMBL
Affinity DataKi: 780nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research and Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research and Development
Curated by ChEMBL
Affinity DataKi: 4.20E+3nMAssay Description:Inhibition of 125[I] Fibrinogen binding to isolated purified human fibrinogen receptorMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research and Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research and Development
Curated by ChEMBL
Affinity DataKi: 5.30E+3nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research and Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research and Development
Curated by ChEMBL
Affinity DataKi: <1.00E+4nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research and Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research and Development
Curated by ChEMBL
Affinity DataKi: 1.45E+4nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals Research and Development
Curated by ChEMBL
Smithkline Beecham Pharmaceuticals Research and Development
Curated by ChEMBL
Affinity DataKi: 6.20E+4nMAssay Description:Inhibition of canine platelet-rich plasma agregation induced by ADPMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Compound wastested for inhibition of porcine secreted pancreatic PLA2More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Compound was tested for inhibition of porcine secretory pancreatic Phospholipase A2More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Astrazeneca
US Patent
Astrazeneca
US Patent
Affinity DataIC50: 7nMT: 2°CAssay Description:The inhibition of PI3K-beta, PI3K-alpha, PI3K-gamma and PI3K-delta was evaluated in a Kinase Glo based enzyme activity assay using human recombinant ...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Astrazeneca
US Patent
Astrazeneca
US Patent
Affinity DataIC50: <10nMT: 2°CAssay Description:The inhibition of PI3K-beta, PI3K-alpha, PI3K-gamma and PI3K-delta was evaluated in a Kinase Glo based enzyme activity assay using human recombinant ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Astrazeneca
US Patent
Astrazeneca
US Patent
Affinity DataIC50: <10nMT: 2°CAssay Description:The inhibition of PI3K-beta, PI3K-alpha, PI3K-gamma and PI3K-delta was evaluated in a Kinase Glo based enzyme activity assay using human recombinant ...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Astrazeneca
US Patent
Astrazeneca
US Patent
Affinity DataIC50: <10nMT: 2°CAssay Description:The inhibition of PI3K-beta, PI3K-alpha, PI3K-gamma and PI3K-delta was evaluated in a Kinase Glo based enzyme activity assay using human recombinant ...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through chromogenic assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Astrazeneca
US Patent
Astrazeneca
US Patent
Affinity DataIC50: 12nMT: 2°CAssay Description:The inhibition of PI3K-beta, PI3K-alpha, PI3K-gamma and PI3K-delta was evaluated in a Kinase Glo based enzyme activity assay using human recombinant ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Astrazeneca
US Patent
Astrazeneca
US Patent
Affinity DataIC50: <12nMT: 2°CAssay Description:The inhibition of PI3K-beta, PI3K-alpha, PI3K-gamma and PI3K-delta was evaluated in a Kinase Glo based enzyme activity assay using human recombinant ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Astrazeneca
US Patent
Astrazeneca
US Patent
Affinity DataIC50: 12nMT: 2°CAssay Description:The inhibition of PI3K-beta, PI3K-alpha, PI3K-gamma and PI3K-delta was evaluated in a Kinase Glo based enzyme activity assay using human recombinant ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Astrazeneca
US Patent
Astrazeneca
US Patent
Affinity DataIC50: <12nMT: 2°CAssay Description:The inhibition of PI3K-beta, PI3K-alpha, PI3K-gamma and PI3K-delta was evaluated in a Kinase Glo based enzyme activity assay using human recombinant ...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human nonpancreatic secretory Phospholipase A2 through DOC/PC assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Astrazeneca
US Patent
Astrazeneca
US Patent
Affinity DataIC50: <14nMT: 2°CAssay Description:The inhibition of PI3K-beta, PI3K-alpha, PI3K-gamma and PI3K-delta was evaluated in a Kinase Glo based enzyme activity assay using human recombinant ...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against porcine pancreatic Phospholipase A2More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Astrazeneca
US Patent
Astrazeneca
US Patent
Affinity DataIC50: <14nMT: 2°CAssay Description:The inhibition of PI3K-beta, PI3K-alpha, PI3K-gamma and PI3K-delta was evaluated in a Kinase Glo based enzyme activity assay using human recombinant ...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Compound was tested for inhibition of porcine secretory pancreatic Phospholipase A2More data for this Ligand-Target Pair