TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Affymax
Curated by ChEMBL
Affymax
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B using O-methyl fluorescein monophosphateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Affymax
Curated by ChEMBL
Affymax
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B using O-methyl fluorescein monophosphateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Affymax
Curated by ChEMBL
Affymax
Curated by ChEMBL
Affinity DataKi: 53nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B using O-methyl fluorescein monophosphateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Affymax
Curated by ChEMBL
Affymax
Curated by ChEMBL
Affinity DataKi: 56nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B using O-methyl fluorescein monophosphateMore data for this Ligand-Target Pair
Affinity DataKi: 92nMAssay Description:Inhibition of human dihydrofolate reductase assessed as inhibition constant by UV-Vis spectra based Benesi Hilebrand equation analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Affymax
Curated by ChEMBL
Affymax
Curated by ChEMBL
Affinity DataKi: 98nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B using O-methyl fluorescein monophosphateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Affymax
Curated by ChEMBL
Affymax
Curated by ChEMBL
Affinity DataKi: 590nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B using O-methyl fluorescein monophosphateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Affymax
Curated by ChEMBL
Affymax
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B using O-methyl fluorescein monophosphateMore data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nMAssay Description:Inhibition of human dihydrofolate reductase assessed as inhibition constant by UV-Vis spectra based Benesi Hilebrand equation analysisMore data for this Ligand-Target Pair
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Affymax Research Institute
Curated by ChEMBL
Affymax Research Institute
Curated by ChEMBL
Affinity DataKi: 4.00E+3nMAssay Description:Compound was tested for inhibition of human phosphomannose isomerase (PMI)More data for this Ligand-Target Pair
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Affymax Research Institute
Curated by ChEMBL
Affymax Research Institute
Curated by ChEMBL
Affinity DataKi: 4.00E+3nMAssay Description:Compound was tested for inhibition of yeast phosphomannose isomerase (PMI)More data for this Ligand-Target Pair
Affinity DataKi: 2.01E+4nMAssay Description:Inhibition of rabbit liver guanaseMore data for this Ligand-Target Pair
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Affymax Research Institute
Curated by ChEMBL
Affymax Research Institute
Curated by ChEMBL
Affinity DataKi: 2.60E+4nMAssay Description:Compound was evaluated for the inhibition constant against phosphomannose isomerase enzyme of Candida albicans (CaPMI)More data for this Ligand-Target Pair
Affinity DataKi: 5.36E+4nMAssay Description:Inhibition of rabbit liver guanaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in baculovirus expression system using Rh-EVNLDAEFK-Quencher as substrate after 90 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human dihydrofolate reductase using dihydrofolic acid as substrate preincubated for 1 hr in presence of NADPH followed by substrate add...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human dihydrofolate reductase using dihydrofolic acid as substrate preincubated for 1 hr in presence of NADPH followed by substrate add...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Affymax
Curated by ChEMBL
Affymax
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B using O-methyl fluorescein monophosphateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Affymax
Curated by ChEMBL
Affymax
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B using O-methyl fluorescein monophosphateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Affymax
Curated by ChEMBL
Affymax
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B using O-methyl fluorescein monophosphateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Affymax
Curated by ChEMBL
Affymax
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B using O-methyl fluorescein monophosphateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Affymax
Curated by ChEMBL
Affymax
Curated by ChEMBL
Affinity DataIC50: 74nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B using O-methyl fluorescein monophosphateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Affymax
Curated by ChEMBL
Affymax
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in baculovirus expression system using Rh-EVNLDAEFK-Quencher as substrate after 90 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human dihydrofolate reductase using dihydrofolic acid as substrate preincubated for 1 hr in presence of NADPH followed by substrate add...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 116nMAssay Description:Inhibition of Bcr-Abl (unknown origin) phosphorylation by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 119nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in baculovirus expression system using Rh-EVNLDAEFK-Quencher as substrate after 90 mins by FRET assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Affymax
Curated by ChEMBL
Affymax
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B using O-methyl fluorescein monophosphateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Affymax
Curated by ChEMBL
Affymax
Curated by ChEMBL
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Affymax
Curated by ChEMBL
Affymax
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B using O-methyl fluorescein monophosphateMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of human dihydrofolate reductase using dihydrofolic acid as substrate preincubated for 1 hr in presence of NADPH followed by substrate add...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Affymax
Curated by ChEMBL
Affymax
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B using O-methyl fluorescein monophosphateMore data for this Ligand-Target Pair
Affinity DataIC50: 326nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in baculovirus expression system using Rh-EVNLDAEFK-Quencher as substrate after 90 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 503nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in baculovirus expression system using Rh-EVNLDAEFK-Quencher as substrate after 90 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 578nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in baculovirus expression system using Rh-EVNLDAEFK-Quencher as substrate after 90 mins by FRET assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Affymax
Curated by ChEMBL
Affymax
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B using O-methyl fluorescein monophosphateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Affymax
Curated by ChEMBL
Affymax
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B using O-methyl fluorescein monophosphateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Affymax
Curated by ChEMBL
Affymax
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B using O-methyl fluorescein monophosphateMore data for this Ligand-Target Pair
Affinity DataIC50: 670nMAssay Description:Inhibition of human dihydrofolate reductase using dihydrofolic acid as substrate preincubated for 1 hr in presence of NADPH followed by substrate add...More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataIC50: 740nMAssay Description:Inhibition of Bcr-Abl (unknown origin) phosphorylation by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 741nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in baculovirus expression system using Rh-EVNLDAEFK-Quencher as substrate after 90 mins by FRET assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Affymax
Curated by ChEMBL
Affymax
Curated by ChEMBL
Affinity DataIC50: 770nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B using O-methyl fluorescein monophosphateMore data for this Ligand-Target Pair
Affinity DataIC50: 849nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in baculovirus expression system using Rh-EVNLDAEFK-Quencher as substrate after 90 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 854nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in baculovirus expression system using Rh-EVNLDAEFK-Quencher as substrate after 90 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 928nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in baculovirus expression system using Rh-EVNLDAEFK-Quencher as substrate after 90 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human dihydrofolate reductase using dihydrofolic acid as substrate preincubated for 1 hr in presence of NADPH followed by substrate add...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Affymax
Curated by ChEMBL
Affymax
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B using O-methyl fluorescein monophosphateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Affymax
Curated by ChEMBL
Affymax
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B using O-methyl fluorescein monophosphateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Affymax
Curated by ChEMBL
Affymax
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B using O-methyl fluorescein monophosphateMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Affymax
Curated by ChEMBL
Affymax
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B using O-methyl fluorescein monophosphateMore data for this Ligand-Target Pair