BindingDB PrimarySearch_ki

Found 287 with Last Name = 'bhatt' and Initial = 'p'

Sigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Yeditepe University

Curated by ChEMBL

PNG

BDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)

Ki: 6.30nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

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3D Structure (crystal)

Glutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50083351((+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-...)

Ki: 10nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B NMDA receptor (unknown origin) expressed in dexamethasone-induced mouse L-M(TK-) cell af...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
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PDB

3D Structure (crystal)

Sigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Yeditepe University

Curated by ChEMBL

PNG

BDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)

Ki: 15nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

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Sigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593147(CHEMBL5203777)

Ki: 24nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Sigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593148(CHEMBL5204934)

Ki: 35nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Sigma intracellular receptor 2(Rattus norvegicus (Rat))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50009307(DITOLYLGUANIDINE | Di-o-tolylguanidine)

Ki: 57nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

UniProtKB/SwissProt
GoogleScholar

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Glutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593148(CHEMBL5204934)

Ki: 60nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B NMDA receptor (unknown origin) expressed in dexamethasone-induced mouse L-M(TK-) cell af...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Sigma intracellular receptor 2(Rattus norvegicus (Rat))
Yeditepe University

Curated by ChEMBL

PNG

BDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)

Ki: 78nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

UniProtKB/SwissProt
GoogleScholar

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Sigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50009307(DITOLYLGUANIDINE | Di-o-tolylguanidine)

Ki: 89nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
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Sigma intracellular receptor 2(Rattus norvegicus (Rat))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50083351((+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-...)

Ki: 98nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

UniProtKB/SwissProt
GoogleScholar

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Sigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593146(CHEMBL5207817)

Ki: 109nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Glutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593145(CHEMBL5192784)

Ki: 115nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B NMDA receptor (unknown origin) expressed in dexamethasone-induced mouse L-M(TK-) cell af...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Sigma intracellular receptor 2(Rattus norvegicus (Rat))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593150(CHEMBL5205006)

Ki: 121nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

UniProtKB/SwissProt
GoogleScholar

Sigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50083351((+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-...)

Ki: 125nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
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Sigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593140(CHEMBL5171428)

Ki: 147nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Sigma intracellular receptor 2(Rattus norvegicus (Rat))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593145(CHEMBL5192784)

Ki: 158nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

UniProtKB/SwissProt
GoogleScholar

Glutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593154(CHEMBL5206534)

Ki: 184nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B NMDA receptor (unknown origin) expressed in dexamethasone-induced mouse L-M(TK-) cell af...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Glutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593152(CHEMBL5176580)

Ki: 187nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B NMDA receptor (unknown origin) expressed in dexamethasone-induced mouse L-M(TK-) cell af...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Sigma intracellular receptor 2(Rattus norvegicus (Rat))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593140(CHEMBL5171428)

Ki: 200nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

UniProtKB/SwissProt
GoogleScholar

Glutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593150(CHEMBL5205006)

Ki: 202nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B NMDA receptor (unknown origin) expressed in dexamethasone-induced mouse L-M(TK-) cell af...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Sigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593141(CHEMBL5192987)

Ki: 204nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Glutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593147(CHEMBL5203777)

Ki: 213nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B NMDA receptor (unknown origin) expressed in dexamethasone-induced mouse L-M(TK-) cell af...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Glutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593141(CHEMBL5192987)

Ki: 229nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B NMDA receptor (unknown origin) expressed in dexamethasone-induced mouse L-M(TK-) cell af...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Sigma intracellular receptor 2(Rattus norvegicus (Rat))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593147(CHEMBL5203777)

Ki: 233nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

UniProtKB/SwissProt
GoogleScholar

Sigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593158(CHEMBL5172256)

Ki: 238nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Sigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593145(CHEMBL5192784)

Ki: 238nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Sigma intracellular receptor 2(Rattus norvegicus (Rat))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593158(CHEMBL5172256)

Ki: 238nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

UniProtKB/SwissProt
GoogleScholar

Glutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593146(CHEMBL5207817)

Ki: 457nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B NMDA receptor (unknown origin) expressed in dexamethasone-induced mouse L-M(TK-) cell af...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Glutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593140(CHEMBL5171428)

Ki: 476nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B NMDA receptor (unknown origin) expressed in dexamethasone-induced mouse L-M(TK-) cell af...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Sigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593155(CHEMBL5206663)

Ki: 505nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Sigma intracellular receptor 2(Rattus norvegicus (Rat))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593148(CHEMBL5204934)

Ki: 519nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

UniProtKB/SwissProt
GoogleScholar

Sigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593138(CHEMBL5185552)

Ki: 543nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Sigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593143(CHEMBL5194197)

Ki: 570nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Sigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593144(CHEMBL5203299)

Ki: 575nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Sigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593150(CHEMBL5205006)

Ki: 809nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Sigma intracellular receptor 2(Rattus norvegicus (Rat))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593159(CHEMBL5198012)

Ki: >1.00E+3nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

UniProtKB/SwissProt
GoogleScholar

Glutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593138(CHEMBL5185552)

Ki: >1.00E+3nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B NMDA receptor (unknown origin) expressed in dexamethasone-induced mouse L-M(TK-) cell af...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Glutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593139(CHEMBL5183248)

Ki: >1.00E+3nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B NMDA receptor (unknown origin) expressed in dexamethasone-induced mouse L-M(TK-) cell af...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Glutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593142(CHEMBL5207906)

Ki: >1.00E+3nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B NMDA receptor (unknown origin) expressed in dexamethasone-induced mouse L-M(TK-) cell af...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Glutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593144(CHEMBL5203299)

Ki: >1.00E+3nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B NMDA receptor (unknown origin) expressed in dexamethasone-induced mouse L-M(TK-) cell af...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Glutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593149(CHEMBL5198839)

Ki: >1.00E+3nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B NMDA receptor (unknown origin) expressed in dexamethasone-induced mouse L-M(TK-) cell af...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Glutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593151(CHEMBL5178466)

Ki: >1.00E+3nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B NMDA receptor (unknown origin) expressed in dexamethasone-induced mouse L-M(TK-) cell af...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Glutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593153(CHEMBL5177298)

Ki: >1.00E+3nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B NMDA receptor (unknown origin) expressed in dexamethasone-induced mouse L-M(TK-) cell af...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Glutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593155(CHEMBL5206663)

Ki: >1.00E+3nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B NMDA receptor (unknown origin) expressed in dexamethasone-induced mouse L-M(TK-) cell af...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Glutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593156(CHEMBL5173420)

Ki: >1.00E+3nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B NMDA receptor (unknown origin) expressed in dexamethasone-induced mouse L-M(TK-) cell af...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Glutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593157(CHEMBL5193082)

Ki: >1.00E+3nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B NMDA receptor (unknown origin) expressed in dexamethasone-induced mouse L-M(TK-) cell af...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Glutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593158(CHEMBL5172256)

Ki: >1.00E+3nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B NMDA receptor (unknown origin) expressed in dexamethasone-induced mouse L-M(TK-) cell af...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Glutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593159(CHEMBL5198012)

Ki: >1.00E+3nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B NMDA receptor (unknown origin) expressed in dexamethasone-induced mouse L-M(TK-) cell af...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Sigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593142(CHEMBL5207906)

Ki: 1.00E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Sigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Yeditepe University

Curated by ChEMBL

PNG

BDBM50593151(CHEMBL5178466)

Ki: 1.00E+3nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
GoogleScholar

Displayed 1 to 50 (of 287 total ) | Next | Last >>

Filter my 287 hits

Targets 14▿
- Macrophage migration inhibitory factor 54
- Sterol O-acyltransferase 2 45
- Sterol O-acyltransferase 1 38
- Sigma non-opioid intracellular receptor 1 26
- Sigma intracellular receptor 2 25
- Acetylcholinesterase 25
- Cholinesterase 25
- Glutamate receptor ionotropic, NMDA 2B 23
- Adenosine receptor A3 17
- P2X purinoceptor 7 5
- Phospholipase A2 1
- Cytochrome P450 2C9 1
- Cytochrome P450 2D6 1
- Cytochrome P450 3A4 1
- ...
Publications 4▿
- J Med Chem 65: 12292-12318 (2022) 132
- Bioorg Med Chem Lett 19: 4773-6 (2009) 54
- Bioorg Med Chem Lett 15: 3737-43 (2005) 17
- Bioorg Med Chem Lett 23: 6234-8 (2013) 1
Institutions 4▿
- Yeditepe University 132
- Piramal Life Sciences 54
- Jadavpur University 17
- Csir-Iict 1
Affinity: 0.90 to 6.2E+6 nM▿
- Ki 91
- IC50 196
- Affinity ≤ nM
Xtal structures: 6
Docked structures: 0
Catalog Cmpds: 9