Compile Data Set for Download or QSAR
maximum 50k data
Found 33 Enz. Inhib. hit(s) with Target = 'Sigma intracellular receptor 2' and Ligand = 'BDBM21398'
TargetSigma intracellular receptor 2(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor (unknown origin) incubated for 1 hr in presence of (+)SKF10047 by liquid scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]-DTG from sigma 2 receptor (unknown origin) after 120 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  16nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin) assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSigma intracellular receptor 2(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]-DTG from sigma2 receptor (unknown origin) incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  18nMAssay Description:Compound was evaluated for inhibition of porcine plasma Angiotensin I converting enzyme by using fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  21nMAssay Description:Displacement of (+)-[3H]DTG from sigma 2 receptor in SPRD rat liver membrane incubated for 2 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  35nMAssay Description:Displacement of [125I]-RHM-4 from sigma 2 receptor in rat liver membranes after 120 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]DTG from sigma2 receptor in rat liver membranes after 60 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  77nMAssay Description:Displacement of [3H]-DTG from Sprague-Dawley rat liver Sigma 2 receptor incubated for 120 mins in presence of [3H]-(+)-pentazocine by liquid scintill...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]-Di-o-tolylguanidine from sigma-2 receptor in rat liver membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membranes incubated for 120 mins in the presence of sigma1 receptor ligand...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membrane incubated for 120 mins by liquid scintillation counting method re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in rat liver membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]-Di-o-tolylguanidine from sigma-2 receptor in rat liver membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]DTG from sigma2 receptor in rat liver membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membranes incubated for 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membranes in the presence of sigma1 receptor ligand (+)-pentazocine incuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]di-o-tolylguanidine from sigma2 receptor in rat liver membranes measured after 120 mins by solid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma-2 receptor in rat liver membranes incubated for 120 mins measured for 5 mins by scintillation cou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]-DTG from sigma 2 receptor in rat liver membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]-DTG from sigma2 receptor in rat liver membranes after 120 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membrane incubated for 120 mins measured for 5 mins by scintillation count...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]DTG from sigma-2 receptor in rat liver membranes after 120 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]di-O-tolylguanidine from sigma 2 receptor in rat liver membrane by competitive radioligand receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membrane measured by competitive radioligand receptor binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]-DTG from sigma 2 receptor in rat liver membrane measured after 120 mins by microbeta counting analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  78nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membrane by solid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  81nMAssay Description:Displacement of [3H]-DTG from sigma2 receptor in rat brain membranes after 120 mins in presence of (+)-pentazocine by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  83nMAssay Description:Displacement of [3H]-DTG from sigma-2 receptor in human Jurkat cell membrane incubated for 1 hr by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  114nMAssay Description:Displacement of [3H]DTG from sigma-2 receptor in Sprague-Dawley rat liver membrane incubated for 90 mins in presence of by liquid scintillation count...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Helmholtz-Zentrum Dresden-Rossendor

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  125nMAssay Description:Displacement of [3H]DTG from sigma2 receptor in rat liver membranes after 120 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  221nMAssay Description:Binding affinity to sigma-2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed