Compile Data Set for Download or QSAR
maximum 50k data
Found 45 with Last Name = 'bhuiyan' and Initial = 'mp'
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222732((5S,11S,13aR)-5-benzyl-8,8-dimethyl-11-[5-(pyridin...)
Affinity DataIC50:  18nMAssay Description:Inhibition of HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute of Technology

LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  19nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  20nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50223507((1R,14S,20R,23S)-23-[5-(Pyridin-2-yldisulfanyl)-pe...)
Affinity DataIC50:  20nMAssay Description:Inhibition of HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50223505((5S,11S,13aR)-5-((S)-sec-butyl)-8,8-dimethyl-11-[5...)
Affinity DataIC50:  23nMAssay Description:Inhibition of HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50223506((5S,11S,13aR)-5-butyl-8,8-dimethyl-11-[5-(pyridin-...)
Affinity DataIC50:  24nMAssay Description:Inhibition of HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Kyushu Institute of Technology

LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  28nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50223504((5S,11S,13aR)-5-isobutyl-8,8-dimethyl-11-[5-(pyrid...)
Affinity DataIC50:  33nMAssay Description:Inhibition of HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute of Technology

LigandPNGBDBM50223507((1R,14S,20R,23S)-23-[5-(Pyridin-2-yldisulfanyl)-pe...)
Affinity DataIC50:  35nMAssay Description:Inhibition of HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute of Technology

LigandPNGBDBM50223506((5S,11S,13aR)-5-butyl-8,8-dimethyl-11-[5-(pyridin-...)
Affinity DataIC50:  38nMAssay Description:Inhibition of HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute of Technology

LigandPNGBDBM50223505((5S,11S,13aR)-5-((S)-sec-butyl)-8,8-dimethyl-11-[5...)
Affinity DataIC50:  38nMAssay Description:Inhibition of HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute of Technology

LigandPNGBDBM50222732((5S,11S,13aR)-5-benzyl-8,8-dimethyl-11-[5-(pyridin...)
Affinity DataIC50:  39nMAssay Description:Inhibition of HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222727((5S,11S,13aR)-5,8,8-trimethyl-11-[5-(pyridin-2-yld...)
Affinity DataIC50:  52nMAssay Description:Inhibition of HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute of Technology

LigandPNGBDBM50223504((5S,11S,13aR)-5-isobutyl-8,8-dimethyl-11-[5-(pyrid...)
Affinity DataIC50:  58nMAssay Description:Inhibition of HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM19158((3S,9S,14aR)-9-benzyl-3-(7-bromo-6-oxoheptyl)-6,6-...)
Affinity DataIC50:  59.5nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM19162((3S,9S,14aR)-9-benzyl-3-(7-hydroxy-6-oxoheptyl)-6,...)
Affinity DataIC50:  60.4nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute of Technology

LigandPNGBDBM19158((3S,9S,14aR)-9-benzyl-3-(7-bromo-6-oxoheptyl)-6,6-...)
Affinity DataIC50:  61.9nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute of Technology

LigandPNGBDBM50222727((5S,11S,13aR)-5,8,8-trimethyl-11-[5-(pyridin-2-yld...)
Affinity DataIC50:  94nMAssay Description:Inhibition of HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute of Technology

LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  190nMAssay Description:Inhibition of HDAC1 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  200nMAssay Description:Inhibition of HDAC4 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute of Technology

LigandPNGBDBM19162((3S,9S,14aR)-9-benzyl-3-(7-hydroxy-6-oxoheptyl)-6,...)
Affinity DataIC50:  223nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50223504((5S,11S,13aR)-5-isobutyl-8,8-dimethyl-11-[5-(pyrid...)
Affinity DataIC50:  230nMAssay Description:Inhibition of HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  280nMAssay Description:Inhibition of HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50223506((5S,11S,13aR)-5-butyl-8,8-dimethyl-11-[5-(pyridin-...)
Affinity DataIC50:  280nMAssay Description:Inhibition of HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM19159((3S,9S,14aR)-9-benzyl-6,6-dimethyl-3-(6-oxoheptyl)...)
Affinity DataIC50:  290nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50223505((5S,11S,13aR)-5-((S)-sec-butyl)-8,8-dimethyl-11-[5...)
Affinity DataIC50:  310nMAssay Description:Inhibition of HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222732((5S,11S,13aR)-5-benzyl-8,8-dimethyl-11-[5-(pyridin...)
Affinity DataIC50:  404nMAssay Description:Inhibition of HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50222727((5S,11S,13aR)-5,8,8-trimethyl-11-[5-(pyridin-2-yld...)
Affinity DataIC50:  430nMAssay Description:Inhibition of HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Kyushu Institute of Technology

LigandPNGBDBM19158((3S,9S,14aR)-9-benzyl-3-(7-bromo-6-oxoheptyl)-6,6-...)
Affinity DataIC50:  621nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Kyushu Institute of Technology

LigandPNGBDBM19162((3S,9S,14aR)-9-benzyl-3-(7-hydroxy-6-oxoheptyl)-6,...)
Affinity DataIC50:  887nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute of Technology

LigandPNGBDBM19159((3S,9S,14aR)-9-benzyl-6,6-dimethyl-3-(6-oxoheptyl)...)
Affinity DataIC50:  1.08E+3nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM19161(6-[(3S,9S,14aR)-9-benzyl-6,6-dimethyl-1,4,7,10-tet...)
Affinity DataIC50:  1.29E+3nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Kyushu Institute of Technology

LigandPNGBDBM19159((3S,9S,14aR)-9-benzyl-6,6-dimethyl-3-(6-oxoheptyl)...)
Affinity DataIC50:  3.70E+3nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM19157((3S,9S,14aR)-9-benzyl-6,6-dimethyl-3-[5-(oxiran-2-...)
Affinity DataIC50:  4.05E+3nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute of Technology

LigandPNGBDBM19161(6-[(3S,9S,14aR)-9-benzyl-6,6-dimethyl-1,4,7,10-tet...)
Affinity DataIC50:  4.33E+3nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute of Technology

LigandPNGBDBM19157((3S,9S,14aR)-9-benzyl-6,6-dimethyl-3-[5-(oxiran-2-...)
Affinity DataIC50:  4.69E+3nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM50223507((1R,14S,20R,23S)-23-[5-(Pyridin-2-yldisulfanyl)-pe...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of HDAC6 expressed in 293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Kyushu Institute of Technology

LigandPNGBDBM19161(6-[(3S,9S,14aR)-9-benzyl-6,6-dimethyl-1,4,7,10-tet...)
Affinity DataIC50:  1.41E+4nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Kyushu Institute of Technology

LigandPNGBDBM19157((3S,9S,14aR)-9-benzyl-6,6-dimethyl-3-[5-(oxiran-2-...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Kyushu Institute of Technology

LigandPNGBDBM19156((3S,9S,14aR)-9-benzyl-3-(hept-6-en-1-yl)-6,6-dimet...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM19160((3S,9S,14aR)-9-benzyl-3-(6,7-dihydroxyheptyl)-6,6-...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering

Curated by ChEMBL
LigandPNGBDBM19156((3S,9S,14aR)-9-benzyl-3-(hept-6-en-1-yl)-6,6-dimet...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute of Technology

LigandPNGBDBM19160((3S,9S,14aR)-9-benzyl-3-(6,7-dihydroxyheptyl)-6,6-...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Kyushu Institute of Technology

LigandPNGBDBM19156((3S,9S,14aR)-9-benzyl-3-(hept-6-en-1-yl)-6,6-dimet...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
Kyushu Institute of Technology

LigandPNGBDBM19160((3S,9S,14aR)-9-benzyl-3-(6,7-dihydroxyheptyl)-6,6-...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed