Compile Data Set for Download or QSAR
maximum 50k data
Found 100 with Last Name = 'biamonte' and Initial = 'ma'
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM20926(5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-N-ethyl-4-...)
Affinity DataKi:  0.0640nMAssay Description:Binding affinity to HSP90 under reducing conditions in presence of TECPMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM20926(5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-N-ethyl-4-...)
Affinity DataKi:  0.0690nMAssay Description:Binding affinity to HSP90 under non-reducing conditions in absence of TECPMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50401333(CHEMBL1230584)
Affinity DataKi:  0.200nMAssay Description:Binding affinity at recombinant Hsp90alpha incubated for 16 hrs by fluorescence polarization competition assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50378702(CHEMBL560895 | SNX-2112)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to HSP90 under reducing conditions in presence of TECPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM20800(2-amino-6-halopurine analogue, 20 | 6-chloro-9-[(4...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of HSP90alphaMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM20800(2-amino-6-halopurine analogue, 20 | 6-chloro-9-[(4...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity at recombinant Hsp90alpha incubated for 16 hrs by fluorescence polarization competition assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM20800(2-amino-6-halopurine analogue, 20 | 6-chloro-9-[(4...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to HSP90 by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50378702(CHEMBL560895 | SNX-2112)
Affinity DataKi:  2.80nMAssay Description:Binding affinity to HSP90 under non-reducing conditions in absence of TECPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50030868((8S,9S,12S,13R,14S,16R)-19-amino-13-hydroxy-8,14-d...)
Affinity DataKi:  3nMAssay Description:Binding affinity to HSP90 under reducing conditions in presence of TECPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM15359((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-...)
Affinity DataKi:  4.60nMAssay Description:Inhibition of HSP90alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM20926(5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-N-ethyl-4-...)
Affinity DataKi:  8.20nMAssay Description:Inhibition of HSP90betaMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM20926(5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-N-ethyl-4-...)
Affinity DataKi:  9nMAssay Description:Inhibition of HSP90alphaMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM15359((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-...)
Affinity DataKi:  9nMAssay Description:Binding affinity to HSP90 under reducing conditions in presence of TECPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM20800(2-amino-6-halopurine analogue, 20 | 6-chloro-9-[(4...)
Affinity DataKi:  13nMAssay Description:Binding affinity to HSP90 under reducing conditions in presence of TECPMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50030868((8S,9S,12S,13R,14S,16R)-19-amino-13-hydroxy-8,14-d...)
Affinity DataKi:  21nMAssay Description:Binding affinity to HSP90 under non-reducing conditions in absence of TECPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM20800(2-amino-6-halopurine analogue, 20 | 6-chloro-9-[(4...)
Affinity DataKi:  26nMAssay Description:Binding affinity to HSP90 under non-reducing conditions in absence of TECPMore data for this Ligand-Target Pair
TargetEndoplasmin(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50401333(CHEMBL1230584)
Affinity DataKi:  61nMAssay Description:Binding affinity at Grp94 incubated for 16 hrs by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein 75 kDa, mitochondrial(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50401333(CHEMBL1230584)
Affinity DataKi:  255nMAssay Description:Binding affinity at TRAP1 incubated for 16 hrs by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM15359((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-...)
Affinity DataKi:  530nMAssay Description:Binding affinity to HSP90 under non-reducing conditions in absence of TECPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50401335(CHEMBL2205798)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of Hsp90alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50401336(CHEMBL2205245)
Affinity DataIC50:  1nMAssay Description:Inhibition of Hsp90alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50401333(CHEMBL1230584)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of Hsp90alphaMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50401334(CHEMBL2205799)
Affinity DataIC50:  2nMAssay Description:Inhibition of Hsp90alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50378702(CHEMBL560895 | SNX-2112)
Affinity DataIC50:  3nMAssay Description:Inhibition of Hsp90alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50401332(CHEMBL2205800)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of Hsp90alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM20800(2-amino-6-halopurine analogue, 20 | 6-chloro-9-[(4...)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of Hsp90alphaMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50401337(CHEMBL2205244)
Affinity DataIC50:  6nMAssay Description:Inhibition of Hsp90alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM20926(5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-N-ethyl-4-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradation in human MCF7 cellsMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM20800(2-amino-6-halopurine analogue, 20 | 6-chloro-9-[(4...)
Affinity DataIC50:  7nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradationMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM20926(5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-N-ethyl-4-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradationMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50378702(CHEMBL560895 | SNX-2112)
Affinity DataIC50:  7nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50030868((8S,9S,12S,13R,14S,16R)-19-amino-13-hydroxy-8,14-d...)
Affinity DataIC50:  7nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM15359((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM20926(5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-N-ethyl-4-...)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of HSP90alphaMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM15359((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-...)
Affinity DataIC50:  12nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradation in human MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50030868((8S,9S,12S,13R,14S,16R)-19-amino-13-hydroxy-8,14-d...)
Affinity DataIC50:  12nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradation in human MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM20926(5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-N-ethyl-4-...)
Affinity DataIC50:  21nMAssay Description:Inhibition of HSP90betaMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50378702(CHEMBL560895 | SNX-2112)
Affinity DataIC50:  22nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradation in human MCF7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM20800(2-amino-6-halopurine analogue, 20 | 6-chloro-9-[(4...)
Affinity DataIC50:  38nMAssay Description:Inhibition of HSP90-mediated client protein HER2 degradation in human MCF7 cellsMore data for this Ligand-Target Pair
TargetEndoplasmin(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM20926(5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-N-ethyl-4-...)
Affinity DataIC50:  85nMAssay Description:Inhibition of Grp94More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein 75 kDa, mitochondrial(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM20926(5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-N-ethyl-4-...)
Affinity DataIC50:  535nMAssay Description:Inhibition of TRAP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine--tRNA ligase(Homo sapiens (Human))
Drug Discovery For Tropical Diseases

Curated by ChEMBL
LigandPNGBDBM50434379(CLADOSPORIN)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant cytoplasmic lysyl-tRNA synthetaseMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM15374(9-butyl-8-(3,4,5-trimethoxybenzyl)-9H-purin-6-amin...)
Affinity DataEC50:  4.00E+4nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM20926(5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-N-ethyl-4-...)
Affinity DataEC50:  7nMAssay Description:Inhibition of HSP90alpha in human MCF7 cells assessed as degradation of Her-2More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM20741(8-benzyladenine analogue, 12b | 9-butyl-8-[(2-chlo...)
Affinity DataEC50:  2.00E+4nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM20742(8-[(2-bromo-5-methoxyphenyl)methyl]-9-butyl-9H-pur...)
Affinity DataEC50:  8.00E+3nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM20743(8-benzyladenine analogue, 12d | 9-butyl-8-[(2-iodo...)
Affinity DataEC50:  5.00E+3nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM20744(8-sulfanyladenine analogue, 18 | 9-butyl-8-[(2,5-d...)
Affinity DataEC50:  3.50E+3nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM20745(8-Sulfanyladenine | 8-[(2-iodo-5-methoxyphenyl)sul...)
Affinity DataEC50:  280nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM20746(8-[(2-iodo-5-methoxyphenyl)sulfanyl]-9-(4-methylpe...)
Affinity DataEC50:  370nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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