Compile Data Set for Download or QSAR
maximum 50k data
Found 177 with Last Name = 'bischoff' and Initial = 'e'
TargetVitamin D3 receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

LigandPNGBDBM36717(1,25(OH)2D3)
Affinity DataKi:  0.5nM ΔG°:  -49.3kJ/molepH: 7.5 T: 2°CAssay Description:VDR in vitro ligand-binding assay using human VDR constructed into a yeast expression plasmid.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

LigandPNGBDBM36722(LG190178)
Affinity DataKi:  150nM ΔG°:  -36.2kJ/molepH: 7.5 T: 2°CAssay Description:VDR in vitro ligand-binding assay using human VDR constructed into a yeast expression plasmid.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

LigandPNGBDBM36721(LG190176)
Affinity DataKi: >1.00E+3nM ΔG°: >-31.8kJ/molepH: 7.5 T: 2°CAssay Description:VDR in vitro ligand-binding assay using human VDR constructed into a yeast expression plasmid.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

LigandPNGBDBM36719(LG190119)
Affinity DataKi: >1.00E+3nM ΔG°: >-31.8kJ/molepH: 7.5 T: 2°CAssay Description:VDR in vitro ligand-binding assay using human VDR constructed into a yeast expression plasmid.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

LigandPNGBDBM36718(LG190090)
Affinity DataKi: >1.00E+3nM ΔG°: >-31.8kJ/molepH: 7.5 T: 2°CAssay Description:VDR in vitro ligand-binding assay using human VDR constructed into a yeast expression plasmid.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D3 receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

LigandPNGBDBM36720(LG190155)
Affinity DataKi: >1.00E+3nM ΔG°: >-31.8kJ/molepH: 7.5 T: 2°CAssay Description:VDR in vitro ligand-binding assay using human VDR constructed into a yeast expression plasmid.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50111902(2-(2-ethoxy-5-(4-methylpiperazin-1-ylsulfonyl)phen...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of Phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50111900(4-[4-Ethoxy-3-(5-methyl-4-oxo-7-propyl-3,4-dihydro...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of Phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50169652(6-(2-Ethoxy-phenyl)-3-methyl-1-propyl-1,5-dihydro-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50169633(7-Cyclopentyl-2-[2-ethoxy-5-(4-methyl-piperazine-1...)
Affinity DataIC50:  1nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50169627(7-Cyclopentyl-2-{2-ethoxy-5-[4-(2-hydroxy-ethyl)-p...)
Affinity DataIC50:  1nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50111902(2-(2-ethoxy-5-(4-methylpiperazin-1-ylsulfonyl)phen...)
Affinity DataIC50:  2nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50169641(2-{2-Ethoxy-5-[4-(2-hydroxy-ethyl)-piperazine-1-su...)
Affinity DataIC50:  5nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50169634(3-Cyclopentyl-5-{2-ethoxy-5-[4-(2-hydroxy-ethyl)-p...)
Affinity DataIC50:  5nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50169635(7-Cyclopentyl-2-(2-ethoxy-phenyl)-5-methyl-3H-imid...)
Affinity DataIC50:  5nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50111897(2-(2-Ethoxy-phenyl)-3,5-dimethyl-7-propyl-3H-imida...)
Affinity DataIC50:  5nMAssay Description:Inhibition of Phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50111897(2-(2-Ethoxy-phenyl)-3,5-dimethyl-7-propyl-3H-imida...)
Affinity DataIC50:  5nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of Phosphodiesterase 5More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50169647(7-Cyclopentyl-2-[2-ethoxy-5-(4-methyl-piperazine-1...)
Affinity DataIC50:  7nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50169639(2-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50:  8nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50169630(6-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50:  8nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50111898(2-(2-Propoxy-phenyl)-9-propyl-1,9-dihydro-purin-6-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50111901(2-(5-(4-methylpiperazin-1-ylsulfonyl)-2-propoxyphe...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50169627(7-Cyclopentyl-2-{2-ethoxy-5-[4-(2-hydroxy-ethyl)-p...)
Affinity DataIC50:  10nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50169625(2-{2-Ethoxy-5-[4-(2-hydroxy-ethyl)-piperazine-1-su...)
Affinity DataIC50:  10nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50169626(2-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50:  10nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50169637(2-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50:  10nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50169634(3-Cyclopentyl-5-{2-ethoxy-5-[4-(2-hydroxy-ethyl)-p...)
Affinity DataIC50:  10nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50169648(3-Cyclopentyl-5-{2-ethoxy-5-[4-(2-hydroxy-ethyl)-p...)
Affinity DataIC50:  10nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50024352(CHEMBL183857)
Affinity DataIC50:  10nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50169643(8-Cyclopentyl-2-{2-ethoxy-5-[4-(2-hydroxy-ethyl)-p...)
Affinity DataIC50:  10nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50169633(7-Cyclopentyl-2-[2-ethoxy-5-(4-methyl-piperazine-1...)
Affinity DataIC50:  10nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50169646(6-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phe...)
Affinity DataIC50:  20nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50169641(2-{2-Ethoxy-5-[4-(2-hydroxy-ethyl)-piperazine-1-su...)
Affinity DataIC50:  20nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50169631(3-Cyclopentyl-5-(2-ethoxy-phenyl)-6H-isoxazolo[4,5...)
Affinity DataIC50:  20nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50169651(8-Cyclopentyl-2-(2-ethoxy-phenyl)-6-methyl-3H-imid...)
Affinity DataIC50:  20nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType 1 InsP3 receptor isoform S2(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50075183(1,4,5-Insp3 | 1D-myo-inositol 1,4,5-triphosphate |...)
Affinity DataIC50:  20nMAssay Description:Binding affinity of compound was determined by its ability to displace specifically bound Inositol 1,4,5-trisphosphate receptor from purified porcine...More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50111899(5-(2-Ethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-...)
Affinity DataIC50:  27nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50169635(7-Cyclopentyl-2-(2-ethoxy-phenyl)-5-methyl-3H-imid...)
Affinity DataIC50:  30nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50169643(8-Cyclopentyl-2-{2-ethoxy-5-[4-(2-hydroxy-ethyl)-p...)
Affinity DataIC50:  30nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50169648(3-Cyclopentyl-5-{2-ethoxy-5-[4-(2-hydroxy-ethyl)-p...)
Affinity DataIC50:  30nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50169624(1-Cyclopentyl-6-[2-ethoxy-5-(4-methyl-piperazine-1...)
Affinity DataIC50:  40nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50169645(2-(2-Ethoxy-phenyl)-6-methyl-8-propyl-3H-imidazo[1...)
Affinity DataIC50:  40nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50111899(5-(2-Ethoxy-phenyl)-1-methyl-3-propyl-1,6-dihydro-...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVitamin D-binding protein(Rattus norvegicus)
Ligand Pharmaceuticals

LigandPNGBDBM36717(1,25(OH)2D3)
Affinity DataIC50:  40nMpH: 7.4 T: 2°CAssay Description:DBP competition binding assay were done using human serum (Scantibodies) or rat serum (Gibco-BRL).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50169651(8-Cyclopentyl-2-(2-ethoxy-phenyl)-6-methyl-3H-imid...)
Affinity DataIC50:  40nMAssay Description:Inhibition of phosphodiesterase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50327527(2-(4-bromophenyl)-N-((7-methoxy-2-(pyridin-4-yl)qu...)
Affinity DataIC50:  44nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50169628(9-Cyclopentyl-2-(2-ethoxy-phenyl)-1,9-dihydro-puri...)
Affinity DataIC50:  50nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50169640(5-(2-Ethoxy-phenyl)-3-propyl-1,6-dihydro-pyrazolo[...)
Affinity DataIC50:  50nMAssay Description:Inhibition of phosphodiesterase 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 177 total ) | Next | Last >>
Jump to: