Affinity DataKi: 0.100nMAssay Description:Functional activity at human CB1 receptor transfected in CHOK1 cells by [35SGTP]gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Functional activity at human CB1 receptor transfected in CHOK1 cells by [35SGTP]gammaS assayMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 0.170nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.330nMAssay Description:Binding affinity to human TGFBR1More data for this Ligand-Target Pair
Affinity DataKi: 0.580nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nM ΔG°: -53.5kJ/mole EC50: 1nMpH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
Affinity DataKi: 0.650nM ΔG°: -53.3kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nM ΔG°: -53.1kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Binding affinity to human TGFBR1More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.700nM ΔG°: -53.1kJ/mole EC50: 0.800nMpH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
Affinity DataKi: 0.830nMAssay Description:Binding affinity to MC4R by membrane filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nM ΔG°: -52.5kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Functional activity at human CB1 receptor transfected in CHOK1 cells by [35SGTP]gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -52.2kJ/mole EC50: 0.820nMpH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Functional activity at human CB1 receptor transfected in CHOK1 cells by [35SGTP]gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Functional activity at human CB1 receptor transfected in CHOK1 cells by [35SGTP]gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Functional activity at human CB1 receptor transfected in CHOK1 cells by [35SGTP]gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Functional activity at human CB1 receptor transfected in CHOK1 cells by [35SGTP]gammaS assayMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nM ΔG°: -51.6kJ/mole EC50: 4.80nMpH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nM ΔG°: -51.4kJ/mole EC50: 0.700nMpH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nM ΔG°: -50.9kJ/mole EC50: 3.10nMpH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
Affinity DataKi: 1.80nM ΔG°: -50.7kJ/mole EC50: 1.60nMpH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nM ΔG°: -50.6kJ/mole EC50: 1.5nMpH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Functional activity at human CB1 receptor transfected in CHOK1 cells by [35SGTP]gammaS assayMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.07nMAssay Description:Binding affinity to human TGFBR1More data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]SR141716 from human CB1 receptor transfected in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
Affinity DataKi: 2.10nM ΔG°: -50.4kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nM ΔG°: -50.1kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibition c...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 8(Homo sapiens (Human))
Millennium Pharmaceuticals
Curated by ChEMBL
Millennium Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Binding affinity to human CCR8 expressed in L1.2 cells by FMAT assayMore data for this Ligand-Target Pair