TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Paris
Curated by ChEMBL
University Of Paris
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human recombinant GST-fused SIRT1 expressed in Escherichia coli DH5-alpha using [3H]acetic acid labeled MPSDKTIGG as substrate after ov...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Université
Curated by ChEMBL
Université
Curated by ChEMBL
Affinity DataIC50: 1.93E+4nMAssay Description:Displacement of biotinylated VEGF165 from human recombinant VEGFR1 by chemiluminescent assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Université
Curated by ChEMBL
Université
Curated by ChEMBL
Affinity DataIC50: 1.94E+4nMAssay Description:Displacement of biotinylated VEGF165 from human recombinant VEGFR1More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Paris
Curated by ChEMBL
University Of Paris
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human recombinant GST-fused SIRT2 expressed in Escherichia coli DH5-alpha using [3H]acetic acid labeled MPSDKTIGG as substrate after ov...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Université
Curated by ChEMBL
Université
Curated by ChEMBL
Affinity DataIC50: 2.29E+4nMAssay Description:Displacement of biotinylated VEGF165 from human recombinant VEGFR1More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Université
Curated by ChEMBL
Université
Curated by ChEMBL
Affinity DataIC50: 2.80E+4nMAssay Description:Displacement of biotinylated VEGF165 from human recombinant VEGFR1 by chemiluminescent assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Université
Curated by ChEMBL
Université
Curated by ChEMBL
Affinity DataIC50: 2.80E+4nMAssay Description:Displacement of biotinylated VEGF165 from human recombinant VEGFR1More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Paris
Curated by ChEMBL
University Of Paris
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human SIRT1 preincubated with enzyme followed by Fluor de Lys substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Université
Curated by ChEMBL
Université
Curated by ChEMBL
Affinity DataIC50: 3.11E+4nMAssay Description:Displacement of biotinylated VEGF165 from human recombinant VEGFR1More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Université
Curated by ChEMBL
Université
Curated by ChEMBL
Affinity DataIC50: 3.99E+4nMAssay Description:Displacement of biotinylated VEGF165 from human recombinant VEGFR1 by chemiluminescent assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Université
Curated by ChEMBL
Université
Curated by ChEMBL
Affinity DataIC50: 9.30E+4nMAssay Description:Displacement of biotinylated VEGF165 from human recombinant VEGFR1More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Université
Curated by ChEMBL
Université
Curated by ChEMBL
Affinity DataIC50: 9.60E+4nMAssay Description:Displacement of biotinylated VEGF165 from human recombinant VEGFR1More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Université
Curated by ChEMBL
Université
Curated by ChEMBL
Affinity DataIC50: 1.21E+5nMAssay Description:Displacement of biotinylated VEGF165 from human recombinant VEGFR1More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Paris
Curated by ChEMBL
University Of Paris
Curated by ChEMBL
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of human SIRT2 preincubated with enzyme followed by Fluor de Lys substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Université
Curated by ChEMBL
Université
Curated by ChEMBL
Affinity DataIC50: 1.51E+5nMAssay Description:Displacement of biotinylated VEGF165 from human recombinant VEGFR1More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Université
Curated by ChEMBL
Université
Curated by ChEMBL
Affinity DataIC50: 1.62E+5nMAssay Description:Displacement of biotinylated VEGF165 from human recombinant VEGFR1More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Université
Curated by ChEMBL
Université
Curated by ChEMBL
Affinity DataIC50: 1.96E+5nMAssay Description:Displacement of biotinylated VEGF-A165 from human VEGFR-1 ECD incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Université
Curated by ChEMBL
Université
Curated by ChEMBL
Affinity DataKd: 6.21E+5nMAssay Description:Binding affinity to 15N-labeled VEGFR1 domain 2 (unknown origin) at 26 mM by TROSY [1H-15N] spectroscopic analysisMore data for this Ligand-Target Pair