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Found 52 with Last Name = 'bowers' and Initial = 'rj'
TargetHeme oxygenase 1(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM31653(CHEMBL421109 | imidazole-dioxolane, 5)
Affinity DataIC50:  520nMAssay Description:In vitro inhibitory concentration against heme oxygenase 1 from rat spleenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183063((2R,4R)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)
Affinity DataIC50:  800nMAssay Description:Inhibition of Sprague-Dawley rat spleen HO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50190798(3-(((2S,4S)-2-((1H-imidazol-1-yl)methyl)-2-(4-chlo...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Sprague-Dawley rat spleen HO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Homo sapiens (Human))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183063((2R,4R)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human spleen HO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM31655(CHEMBL179494 | imidazole-dioxolane, 7)
Affinity DataIC50:  1.60E+3nMAssay Description:In vitro inhibitory concentration against heme oxygenase 1 from rat spleenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM31654(CHEMBL368045 | imidazole-dioxolane, 6)
Affinity DataIC50:  2.50E+3nMAssay Description:In vitro inhibitory concentration against heme oxygenase 1 from rat spleenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183058((2R,4S)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of Sprague-Dawley rat spleen HO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183063((2R,4R)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of rat liver CYP2E1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183062(1-((2-(2-(4-chlorophenyl)ethyl)-1,3-dioxolan-2-yl)...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of Sprague-Dawley rat spleen HO1More data for this Ligand-Target Pair
TargetHeme oxygenase 1(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50161588(3-{(2S,4R)-2-[2-(4-Chloro-phenyl)-ethyl]-2-imidazo...)
Affinity DataIC50:  4.00E+3nMAssay Description:In vitro inhibitory concentration against heme oxygenase 1 from rat spleenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183068(1-((2-(4-chlorophenethyl)-1,3-dithiolan-2-yl)methy...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of Sprague-Dawley rat spleen HO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM31653(CHEMBL421109 | imidazole-dioxolane, 5)
Affinity DataIC50:  5.00E+3nMAssay Description:In vitro inhibitory concentration against heme oxygenase 2 from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50161590(2-{(2S,4S)-2-[2-(4-Chloro-phenyl)-ethyl]-2-imidazo...)
Affinity DataIC50:  5.00E+3nMAssay Description:In vitro inhibitory concentration against heme oxygenase 1 from rat spleenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183062(1-((2-(2-(4-chlorophenyl)ethyl)-1,3-dioxolan-2-yl)...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of rat liver CYP2E1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183058((2R,4S)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of rat liver CYP2E1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50044424(4-(((2S,4S)-2-((1H-imidazol-1-yl)methyl)-2-(4-chlo...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of Sprague-Dawley rat spleen HO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50044424(4-(((2S,4S)-2-((1H-imidazol-1-yl)methyl)-2-(4-chlo...)
Affinity DataIC50:  6.00E+3nMAssay Description:In vitro inhibitory concentration against heme oxygenase 1 from rat spleenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183064((2S,4S)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of Sprague-Dawley rat spleen HO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183068(1-((2-(4-chlorophenethyl)-1,3-dithiolan-2-yl)methy...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of rat liver CYP2E1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50161586(4-{(2S,4R)-2-[2-(4-Chloro-phenyl)-ethyl]-2-imidazo...)
Affinity DataIC50:  1.50E+4nMAssay Description:In vitro inhibitory concentration against heme oxygenase 2 from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183068(1-((2-(4-chlorophenethyl)-1,3-dithiolan-2-yl)methy...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of Sprague-Dawley rat brain HO2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183064((2S,4S)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of rat liver CYP2E1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183069((2S,4R)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of Sprague-Dawley rat spleen HO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50161586(4-{(2S,4R)-2-[2-(4-Chloro-phenyl)-ethyl]-2-imidazo...)
Affinity DataIC50:  2.70E+4nMAssay Description:In vitro inhibitory concentration against heme oxygenase 1 from rat spleenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50044424(4-(((2S,4S)-2-((1H-imidazol-1-yl)methyl)-2-(4-chlo...)
Affinity DataIC50:  2.80E+4nMAssay Description:In vitro inhibitory concentration against heme oxygenase 2 from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50044424(4-(((2S,4S)-2-((1H-imidazol-1-yl)methyl)-2-(4-chlo...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of Sprague-Dawley rat brain HO2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183069((2S,4R)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of rat liver CYP2E1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM31655(CHEMBL179494 | imidazole-dioxolane, 7)
Affinity DataIC50:  3.20E+4nMAssay Description:In vitro inhibitory concentration against heme oxygenase 2 from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183068(1-((2-(4-chlorophenethyl)-1,3-dithiolan-2-yl)methy...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of rat brain nNOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50161588(3-{(2S,4R)-2-[2-(4-Chloro-phenyl)-ethyl]-2-imidazo...)
Affinity DataIC50:  3.40E+4nMAssay Description:In vitro inhibitory concentration against heme oxygenase 2 from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50190798(3-(((2S,4S)-2-((1H-imidazol-1-yl)methyl)-2-(4-chlo...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of Sprague-Dawley rat brain HO2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50044425(4-{(2R,4R)-2-[2-(4-Chloro-phenyl)-ethyl]-2-imidazo...)
Affinity DataIC50:  4.00E+4nMAssay Description:In vitro inhibitory concentration against heme oxygenase 1 from rat spleenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM31654(CHEMBL368045 | imidazole-dioxolane, 6)
Affinity DataIC50:  6.30E+4nMAssay Description:In vitro inhibitory concentration against heme oxygenase 2 from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50161590(2-{(2S,4S)-2-[2-(4-Chloro-phenyl)-ethyl]-2-imidazo...)
Affinity DataIC50:  6.80E+4nMAssay Description:In vitro inhibitory concentration against heme oxygenase 2 from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50161589(2-{(2R,4R)-2-[2-(4-Chloro-phenyl)-ethyl]-2-imidazo...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory concentration against heme oxygenase 1 from rat spleenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50044425(4-{(2R,4R)-2-[2-(4-Chloro-phenyl)-ethyl]-2-imidazo...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory concentration against heme oxygenase 2 from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50161589(2-{(2R,4R)-2-[2-(4-Chloro-phenyl)-ethyl]-2-imidazo...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory concentration against heme oxygenase 2 from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183069((2S,4R)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Sprague-Dawley rat brain HO2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50161591(2-{(2S,4R)-2-[2-(4-Chloro-phenyl)-ethyl]-2-imidazo...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory concentration against heme oxygenase 2 from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50161587(3-{(2R,4R)-2-[2-(4-Chloro-phenyl)-ethyl]-2-imidazo...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory concentration against heme oxygenase 1 from rat spleenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183058((2R,4S)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Sprague-Dawley rat brain HO2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 1(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50161591(2-{(2S,4R)-2-[2-(4-Chloro-phenyl)-ethyl]-2-imidazo...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory concentration against heme oxygenase 1 from rat spleenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183064((2S,4S)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Sprague-Dawley rat brain HO2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183062(1-((2-(2-(4-chlorophenyl)ethyl)-1,3-dioxolan-2-yl)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Sprague-Dawley rat brain HO2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50161587(3-{(2R,4R)-2-[2-(4-Chloro-phenyl)-ethyl]-2-imidazo...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory concentration against heme oxygenase 2 from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183062(1-((2-(2-(4-chlorophenyl)ethyl)-1,3-dioxolan-2-yl)...)
Affinity DataIC50:  1.82E+5nMAssay Description:Inhibition of rat brain nNOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183063((2R,4R)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)
Affinity DataIC50:  3.05E+5nMAssay Description:Inhibition of Sprague-Dawley rat brain HO2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183063((2R,4R)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)
Affinity DataIC50:  3.62E+5nMAssay Description:Inhibition of rat brain nNOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183069((2S,4R)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of rat brain nNOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183064((2S,4S)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of rat brain nNOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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