BDBM50044425 4-{(2R,4R)-2-[2-(4-Chloro-phenyl)-ethyl]-2-imidazol-1-ylmethyl-[1,3]dioxolan-4-ylmethylsulfanyl}-phenylamine::4-{2-[2-(4-Chloro-phenyl)-ethyl]-2-imidazol-1-ylmethyl-[1,3]dioxolan-4-ylmethylsulfanyl}-phenylamine::CHEMBL305220
SMILES Nc1ccc(SC[C@H]2CO[C@@](CCc3ccc(Cl)cc3)(Cn3ccnc3)O2)cc1
InChI Key InChIKey=VYNIUBZKEWJOJP-IFMALSPDSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50044425
Affinity DataKi: 13nMAssay Description:Binding affinity for Cytochrome P450 19A1More data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Syntex Discovery Research
Curated by ChEMBL
Syntex Discovery Research
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Binding affinity for corticoid 11-beta-hydroxylaseMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Binding affinity for progesterone 6-beta-hydroxylase of hepatic microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Inhibition of lanosterol 14-alpha-demethylase of rat hepatic microsomesMore data for this Ligand-Target Pair
TargetLanosterol 14-alpha demethylase(Homo sapiens (Human))
Syntex Discovery Research
Curated by ChEMBL
Syntex Discovery Research
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Inhibition of lanosterol 14-alpha-demethylase in hamster hepatic microsomesMore data for this Ligand-Target Pair
TargetLanosterol 14-alpha demethylase(Homo sapiens (Human))
Syntex Discovery Research
Curated by ChEMBL
Syntex Discovery Research
Curated by ChEMBL
Affinity DataKi: 40.4nMAssay Description:Inhibition of lanosterol 14-alpha-demethylase in hamster hepatic microsomesMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Syntex Discovery Research
Curated by ChEMBL
Syntex Discovery Research
Curated by ChEMBL
Affinity DataKi: 54nMAssay Description:Binding affinity for progesterone 17alpha,20-lyaseMore data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Syntex Discovery Research
Curated by ChEMBL
Syntex Discovery Research
Curated by ChEMBL
Affinity DataKi: 109nMAssay Description:Binding affinity for cholesterol 17-alpha-hydroxylaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+4nMAssay Description:In vitro inhibitory concentration against heme oxygenase 1 from rat spleenMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory concentration against heme oxygenase 2 from rat brainMore data for this Ligand-Target Pair