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Found 94 with Last Name = 'brahma' and Initial = 'mk'
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50436848(CHEMBL2403617)
Affinity DataIC50:  10nMAssay Description:Inhibition of human DGAT1 using [14C]-oleoylCoA/diolein as substrate assessed as formation of [14C]triglyceride after 10 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50354642(CHEMBL1834204)
Affinity DataIC50:  14nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50354637(CHEMBL1834440)
Affinity DataIC50:  14nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50436846(CHEMBL2403620)
Affinity DataIC50:  16nMAssay Description:Inhibition of human DGAT1 using [14C]-oleoylCoA/diolein as substrate assessed as formation of [14C]triglyceride after 10 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50354639(CHEMBL1834201)
Affinity DataIC50:  17nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50354638(CHEMBL1834200)
Affinity DataIC50:  18nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Piramal Healthcare

Curated by ChEMBL
LigandPNGBDBM50402272(CHEMBL2205509)
Affinity DataIC50:  20nMAssay Description:Inhibition of xanthine oxidase using xanthine as substrate at 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50436845(CHEMBL2403621)
Affinity DataIC50:  20nMAssay Description:Inhibition of human DGAT1 using [14C]-oleoylCoA/diolein as substrate assessed as formation of [14C]triglyceride after 10 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM20716((1R,2R)-2-[(4-{4-[(phenylcarbamoyl)amino]phenyl}ph...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM20716((1R,2R)-2-[(4-{4-[(phenylcarbamoyl)amino]phenyl}ph...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human DGAT1 expressed in Sf9 cells assessed as formation of didecanoylglycerol product after 1 hr using 14C-decanoyl-CoA by beta scinti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50436847(CHEMBL2403619)
Affinity DataIC50:  22nMAssay Description:Inhibition of human DGAT1 using [14C]-oleoylCoA/diolein as substrate assessed as formation of [14C]triglyceride after 10 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50436842(CHEMBL2403624)
Affinity DataIC50:  23nMAssay Description:Inhibition of human DGAT1 using [14C]-oleoylCoA/diolein as substrate assessed as formation of [14C]triglyceride after 10 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50436844(CHEMBL2403622)
Affinity DataIC50:  23nMAssay Description:Inhibition of human DGAT1 using [14C]-oleoylCoA/diolein as substrate assessed as formation of [14C]triglyceride after 10 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50354641(CHEMBL1834203)
Affinity DataIC50:  25nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50354631(CHEMBL1834433)
Affinity DataIC50:  28nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50354629(CHEMBL1834431)
Affinity DataIC50:  30nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Piramal Healthcare

Curated by ChEMBL
LigandPNGBDBM50320491(2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-METHYL-5-THIAZOLE...)
Affinity DataIC50:  30nMAssay Description:Inhibition of xanthine oxidase using xanthine as substrate at 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50354634(CHEMBL1834436)
Affinity DataIC50:  32nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50386149(CHEMBL2042351)
Affinity DataIC50:  35nMAssay Description:Inhibition of human DGAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50436841(CHEMBL2403625)
Affinity DataIC50:  37nMAssay Description:Inhibition of human DGAT1 using [14C]-oleoylCoA/diolein as substrate assessed as formation of [14C]triglyceride after 10 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50436839(CHEMBL2403627)
Affinity DataIC50:  49nMAssay Description:Inhibition of human DGAT1 using [14C]-oleoylCoA/diolein as substrate assessed as formation of [14C]triglyceride after 10 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50354633(CHEMBL1834435)
Affinity DataIC50:  51nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50354636(CHEMBL1834438)
Affinity DataIC50:  57nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50436843(CHEMBL2403623)
Affinity DataIC50:  58nMAssay Description:Inhibition of human DGAT1 using [14C]-oleoylCoA/diolein as substrate assessed as formation of [14C]triglyceride after 10 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50354640(CHEMBL1834202)
Affinity DataIC50:  64nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50354630(CHEMBL1834432)
Affinity DataIC50:  72nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50354643(CHEMBL1834206)
Affinity DataIC50:  73nMAssay Description:Inhibition of human DGAT1 expressed in Sf9 cells assessed as formation of didecanoylglycerol product after 1 hr using 14C-decanoyl-CoA by beta scinti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50436840(CHEMBL2403626)
Affinity DataIC50:  82nMAssay Description:Inhibition of human DGAT1 using [14C]-oleoylCoA/diolein as substrate assessed as formation of [14C]triglyceride after 10 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50354632(CHEMBL1834434)
Affinity DataIC50:  88nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50436838(CHEMBL2403628)
Affinity DataIC50:  97nMAssay Description:Inhibition of human DGAT1 using [14C]-oleoylCoA/diolein as substrate assessed as formation of [14C]triglyceride after 10 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50354635(CHEMBL1834437)
Affinity DataIC50:  99nMAssay Description:Inhibition of human DGAT1 assessed as formation of [14C]-triglyceride using [14C]oleoyl-CoA by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Piramal Enterprises

Curated by ChEMBL
LigandPNGBDBM50436837(CHEMBL2403629)
Affinity DataIC50:  101nMAssay Description:Inhibition of human DGAT1 using [14C]-oleoylCoA/diolein as substrate assessed as formation of [14C]triglyceride after 10 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Piramal Healthcare

Curated by ChEMBL
LigandPNGBDBM50402273(CHEMBL2205508)
Affinity DataIC50:  140nMAssay Description:Inhibition of xanthine oxidase using xanthine as substrate at 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Piramal Healthcare

Curated by ChEMBL
LigandPNGBDBM50402280(CHEMBL2205501)
Affinity DataIC50:  310nMAssay Description:Inhibition of xanthine oxidase using xanthine as substrate at 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Piramal Healthcare

Curated by ChEMBL
LigandPNGBDBM50402288(CHEMBL2205498)
Affinity DataIC50:  600nMAssay Description:Inhibition of xanthine oxidase using xanthine as substrate at 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Piramal Healthcare

Curated by ChEMBL
LigandPNGBDBM50402274(CHEMBL2205507)
Affinity DataIC50:  950nMAssay Description:Inhibition of xanthine oxidase using xanthine as substrate at 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Piramal Healthcare

Curated by ChEMBL
LigandPNGBDBM50381872(CHEMBL2022883)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of bovine xanthine oxidase assessed as uric acid formation using xanthine as substrate after 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Piramal Healthcare

Curated by ChEMBL
LigandPNGBDBM50402284(CHEMBL2205495)
Affinity DataIC50:  1.63E+3nMAssay Description:Inhibition of xanthine oxidase using xanthine as substrate at 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Piramal Healthcare

Curated by ChEMBL
LigandPNGBDBM50402275(CHEMBL2205506)
Affinity DataIC50:  1.92E+3nMAssay Description:Inhibition of xanthine oxidase using xanthine as substrate at 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Piramal Healthcare

Curated by ChEMBL
LigandPNGBDBM50402287(CHEMBL2205497)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of xanthine oxidase using xanthine as substrate at 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Piramal Healthcare

Curated by ChEMBL
LigandPNGBDBM50402286(CHEMBL2205496)
Affinity DataIC50:  2.44E+3nMAssay Description:Inhibition of xanthine oxidase using xanthine as substrate at 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Piramal Healthcare

Curated by ChEMBL
LigandPNGBDBM50402278(CHEMBL2205503)
Affinity DataIC50:  2.47E+3nMAssay Description:Inhibition of xanthine oxidase using xanthine as substrate at 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Piramal Healthcare

Curated by ChEMBL
LigandPNGBDBM50402281(CHEMBL2205502)
Affinity DataIC50:  3.65E+3nMAssay Description:Inhibition of xanthine oxidase using xanthine as substrate at 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Piramal Healthcare

Curated by ChEMBL
LigandPNGBDBM35440(ALLOPURINOL | MLS000069453 | SMR000059083 | cid_20...)
Affinity DataIC50:  4.19E+3nMAssay Description:Inhibition of xanthine oxidase using xanthine as substrate at 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Piramal Healthcare

Curated by ChEMBL
LigandPNGBDBM50402283(CHEMBL2205494)
Affinity DataIC50:  4.95E+3nMAssay Description:Inhibition of xanthine oxidase using xanthine as substrate at 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Piramal Healthcare

Curated by ChEMBL
LigandPNGBDBM35440(ALLOPURINOL | MLS000069453 | SMR000059083 | cid_20...)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of bovine xanthine oxidase assessed as uric acid formation using xanthine as substrate after 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Piramal Healthcare

Curated by ChEMBL
LigandPNGBDBM50402276(CHEMBL2205505)
Affinity DataIC50:  6.72E+3nMAssay Description:Inhibition of xanthine oxidase using xanthine as substrate at 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Piramal Healthcare

Curated by ChEMBL
LigandPNGBDBM50402285(CHEMBL2205499)
Affinity DataIC50:  9.24E+3nMAssay Description:Inhibition of xanthine oxidase using xanthine as substrate at 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Piramal Healthcare

Curated by ChEMBL
LigandPNGBDBM50381870(CHEMBL2022881)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of bovine xanthine oxidase assessed as uric acid formation using xanthine as substrate after 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Piramal Healthcare

Curated by ChEMBL
LigandPNGBDBM50402279(CHEMBL2205500)
Affinity DataIC50:  1.65E+4nMAssay Description:Inhibition of xanthine oxidase using xanthine as substrate at 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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