Affinity DataKi: 1.80E+3nMAssay Description:Antagonistic activity against M2 muscarinic receptor in guinea pig left atrium derived by plotting log(DR - 1) vs log[antagonist]More data for this Ligand-Target Pair
Affinity DataKi: 3.60E+3nMAssay Description:Antagonistic activity against M2 muscarinic receptor in guinea pig left atrium derived by plotting log(DR - 1) vs log[antagonist]More data for this Ligand-Target Pair
Affinity DataKi: 4.00E+3nMAssay Description:Antagonistic activity against M2 muscarinic receptor in guinea pig left atrium derived by plotting log(DR - 1) vs log[antagonist]More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+4nMAssay Description:Antagonistic activity against M2 muscarinic receptor in guinea pig left atrium derived by plotting log(DR - 1) vs log[antagonist]More data for this Ligand-Target Pair
Affinity DataKi: 1.70E+4nMAssay Description:Antagonistic activity against M2 muscarinic receptor in guinea pig left atrium derived by plotting log(DR - 1) vs log[antagonist]More data for this Ligand-Target Pair
Affinity DataKi: 1.90E+4nMAssay Description:Antagonistic activity against M2 muscarinic receptor in guinea pig left atrium derived by plotting log(DR - 1) vs log[antagonist]More data for this Ligand-Target Pair
Affinity DataKi: 3.70E+4nMAssay Description:Antagonistic activity against M2 muscarinic receptor in guinea pig left atrium derived by plotting log(DR - 1) vs log[antagonist]More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:In vitro biochemical assays were performed in parallel to determine the most potent tool compound.More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:In vitro biochemical assays were performed in parallel to determine the most potent tool compound.More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:In vitro biochemical assays were performed in parallel to determine the most potent tool compound.More data for this Ligand-Target Pair
Affinity DataIC50: 49nM Kd: 40nMAssay Description:In vitro biochemical assays were performed in parallel to determine the most potent tool compound.More data for this Ligand-Target Pair
Affinity DataIC50: 49nM Kd: 23nMAssay Description:In vitro biochemical assays were performed in parallel to determine the most potent tool compound.More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of PIM1 using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 74nM Kd: 9.5nMAssay Description:In vitro biochemical assays were performed in parallel to determine the most potent tool compound.More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase type II subunit beta(Homo sapiens (Human))
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of CaMK2 using ATP as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of PIM3 using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 145nM Kd: 26nMAssay Description:In vitro biochemical assays were performed in parallel to determine the most potent tool compound.More data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of ROCK2 using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of PIM2 using ATP as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase N2(Homo sapiens (Human))
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of PKN2 using ATP as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase N1(Homo sapiens (Human))
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of PKN1 using ATP as substrateMore data for this Ligand-Target Pair
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of CK1alpha using ATP as substrateMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 5(Homo sapiens (Human))
Turning Point Therapeutics
Curated by ChEMBL
Turning Point Therapeutics
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Antagonist activity at TRPM5 (unknown origin)More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 5(Homo sapiens (Human))
Turning Point Therapeutics
Curated by ChEMBL
Turning Point Therapeutics
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Antagonist activity at TRPM5 (unknown origin)More data for this Ligand-Target Pair
TargetProtein kinase C theta type(Homo sapiens (Human))
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of PKCtheta using ATP as substrateMore data for this Ligand-Target Pair
TargetMAP kinase-activated protein kinase 5(Homo sapiens (Human))
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of MK5 using ATP as substrateMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of PKCalpha using ATP as substrateMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-kinase beta(Homo sapiens (Human))
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PI4Kbeta using ATP as substrateMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of PI3Kgamma using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human GST-Cdc25B expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human GST-Cdc25C expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human GST-Cdc25A expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human GST-Cdc25A expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of PI3Kdelta using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human GST-Cdc25A expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human GST-Cdc25C expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human GST-Cdc25A expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human GST-Cdc25B expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of KDR using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of human GST-Cdc25B expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of RET using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of human GST-Cdc25A expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of human GST-Cdc25C expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of PI3Kbeta using ATP as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of human GST-Cdc25B expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of human GST-Cdc25C expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Affinity DataIC50: >9.10E+3nMAssay Description:Inhibition of VPS34 using ATP as substrateMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Affinity DataIC50: >9.10E+3nMAssay Description:Inhibition of PI3Kalpha using ATP as substrateMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Affinity DataIC50: >9.10E+3nMAssay Description:Inhibition of mTOR using ATP as substrateMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Ludwig-Maximilians University Of Munich
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FLT3 using ATP as substrateMore data for this Ligand-Target Pair