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Target
M-phase inducer phosphatase 3
Ligand
BDBM50197848
Substrate
n/a
Meas. Tech.
ChEMBL_435187 (CHEMBL904570)
IC50
5700±n/a nM
Citation
 Brault, L; Denancé, M; Banaszak, E; El Maadidi, S; Battaglia, E; Bagrel, D; Samadi, M Synthesis and biological evaluation of dialkylsubstituted maleic anhydrides as novel inhibitors of Cdc25 dual specificity phosphatases. Eur J Med Chem 42:243-7 (2007) [PubMed]  Article 
Target
Name:
M-phase inducer phosphatase 3
Synonyms:
CDC25C | Dual specificity phosphatase Cdc25C | M-phase inducer phosphatase 3 | MPIP3_HUMAN
Type:
Substrate
Mol. Mass.:
53366.11
Organism:
Homo sapiens (Human)
Description:
P30307
Residue:
473
Sequence:
MSTELFSSTREEGSSGSGPSFRSNQRKMLNLLLERDTSFTVCPDVPRTPVGKFLGDSANLSILSGGTPKRCLDLSNLSSGEITATQLTTSADLDETGHLDSSGLQEVHLAGMNHDQHLMKCSPAQLLCSTPNGLDRGHRKRDAMCSSSANKENDNGNLVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELMEFSLKDQEAKVSRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYFSGQGKLRKGLCLKKTVSLCDITITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAALLSGKFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRIIIVFHCEFSSERGPRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYCPMHHQDHKTELLRCRSQSKVQEGERQLREQIALLVKDMSP
  
Inhibitor
Name:
BDBM50197848
Synonyms:
3-(4-tridecyl-2,5-dioxo-2,5-dihydrofuran-3-yl)propanoicacid | CHEMBL228410
Type:
Small organic molecule
Emp. Form.:
C20H32O5
Mol. Mass.:
352.4651
SMILES:
CCCCCCCCCCCCCC1=C(CCC(O)=O)C(=O)OC1=O |c:13|
Structure:
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