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Found 80 with Last Name = 'bray-french' and Initial = 'k'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50085135(4-(8-(3-nitrophenyl)-1,7-naphthyridin-6-yl)benzoic...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against Phosphodiesterase 4D (PDE4D) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50085136(8-(3-Nitro-phenyl)-6-phenyl-[1,7]naphthyridine | C...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against Phosphodiesterase 4D (PDE4D) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50085138(4-[8-(3-Chloro-phenyl)-[1,7]naphthyridin-6-yl]-ben...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against Phosphodiesterase 4D (PDE4D) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50085146(8-(3-Nitro-phenyl)-6-pyridin-3-yl-[1,7]naphthyridi...)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against Phosphodiesterase 4D (PDE4D) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50085139(4-[8-(3-Cyano-phenyl)-[1,7]naphthyridin-6-yl]-benz...)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity against Phosphodiesterase 4D (PDE4D) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(RAT)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of phosphodiesterase (PDE) 4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of phosphodiesterase (PDE) 4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of phosphodiesterase (PDE) 4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50085140(6-Allyl-8-(3-nitro-phenyl)-[1,7]naphthyridine | CH...)
Affinity DataIC50:  7nMAssay Description:Inhibitory activity against Phosphodiesterase 4D (PDE4D) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(RAT)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50450772(CHEMBL322092)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of phosphodiesterase (PDE) 4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50450772(CHEMBL322092)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of phosphodiesterase (PDE) 4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50450772(CHEMBL322092)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of phosphodiesterase (PDE) 4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50450770(CHEMBL320307)
Affinity DataIC50:  7.94nMAssay Description:Inhibition of phosphodiesterase (PDE) 4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50085137(6-Furan-2-yl-8-(3-nitro-phenyl)-[1,7]naphthyridine...)
Affinity DataIC50:  8nMAssay Description:Inhibitory activity against Phosphodiesterase 4D (PDE4D) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50450770(CHEMBL320307)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of phosphodiesterase (PDE) 4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(RAT)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50450771(CHEMBL326655)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of phosphodiesterase (PDE) 4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50450771(CHEMBL326655)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of phosphodiesterase (PDE) 4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(RAT)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50450770(CHEMBL320307)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of phosphodiesterase (PDE) 4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50450771(CHEMBL326655)
Affinity DataIC50:  8.80nMAssay Description:Inhibition of phosphodiesterase (PDE) 4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50085141(CHEMBL351900 | Trifluoro-methanesulfonic acid 8-(3...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity against Phosphodiesterase 4D (PDE4D) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(RAT)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50085138(4-[8-(3-Chloro-phenyl)-[1,7]naphthyridin-6-yl]-ben...)
Affinity DataIC50:  45nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50085145(CHEMBL161714 | Trifluoro-methanesulfonic acid 8-(3...)
Affinity DataIC50:  48nMAssay Description:Inhibitory activity against Phosphodiesterase 4D (PDE4D) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(RAT)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50085135(4-(8-(3-nitrophenyl)-1,7-naphthyridin-6-yl)benzoic...)
Affinity DataIC50:  49nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50085138(4-[8-(3-Chloro-phenyl)-[1,7]naphthyridin-6-yl]-ben...)
Affinity DataIC50:  59nMAssay Description:Inhibitory activity against Phosphodiesterase 4A (PDE4A) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50085135(4-(8-(3-nitrophenyl)-1,7-naphthyridin-6-yl)benzoic...)
Affinity DataIC50:  68nMAssay Description:Inhibitory activity against Phosphodiesterase 4C (PDE4C) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50085147(8-(3-Nitro-phenyl)-6-o-tolyl-[1,7]naphthyridine | ...)
Affinity DataIC50:  70nMAssay Description:Inhibitory activity against Phosphodiesterase 4D (PDE4D) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50085143(CHEMBL158286 | Trifluoro-methanesulfonic acid 8-(3...)
Affinity DataIC50:  72nMAssay Description:Inhibitory activity against Phosphodiesterase 4D (PDE4D) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50346088((1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphe...)
Affinity DataIC50:  79nMAssay Description:Inhibitory activity against Phosphodiesterase 4D (PDE4D) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(RAT)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50085146(8-(3-Nitro-phenyl)-6-pyridin-3-yl-[1,7]naphthyridi...)
Affinity DataIC50:  81nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(RAT)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50085139(4-[8-(3-Cyano-phenyl)-[1,7]naphthyridin-6-yl]-benz...)
Affinity DataIC50:  85nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50085135(4-(8-(3-nitrophenyl)-1,7-naphthyridin-6-yl)benzoic...)
Affinity DataIC50:  88nMAssay Description:Inhibitory activity against Phosphodiesterase 4A (PDE4A) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(RAT)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50085136(8-(3-Nitro-phenyl)-6-phenyl-[1,7]naphthyridine | C...)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50085146(8-(3-Nitro-phenyl)-6-pyridin-3-yl-[1,7]naphthyridi...)
Affinity DataIC50:  120nMAssay Description:Inhibitory activity against Phosphodiesterase 4A (PDE4A) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50085139(4-[8-(3-Cyano-phenyl)-[1,7]naphthyridin-6-yl]-benz...)
Affinity DataIC50:  140nMAssay Description:Inhibitory activity against Phosphodiesterase 4A (PDE4A) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(RAT)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50085140(6-Allyl-8-(3-nitro-phenyl)-[1,7]naphthyridine | CH...)
Affinity DataIC50:  150nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50085138(4-[8-(3-Chloro-phenyl)-[1,7]naphthyridin-6-yl]-ben...)
Affinity DataIC50:  190nMAssay Description:Inhibitory activity against Phosphodiesterase 4C (PDE4C) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50085140(6-Allyl-8-(3-nitro-phenyl)-[1,7]naphthyridine | CH...)
Affinity DataIC50:  279nMAssay Description:Inhibitory activity against Phosphodiesterase 4A (PDE4A) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(RAT)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50085141(CHEMBL351900 | Trifluoro-methanesulfonic acid 8-(3...)
Affinity DataIC50:  310nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(RAT)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50346088((1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphe...)
Affinity DataIC50:  310nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(RAT)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50085147(8-(3-Nitro-phenyl)-6-o-tolyl-[1,7]naphthyridine | ...)
Affinity DataIC50:  340nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50085136(8-(3-Nitro-phenyl)-6-phenyl-[1,7]naphthyridine | C...)
Affinity DataIC50:  350nMAssay Description:Inhibitory activity against Phosphodiesterase 4A (PDE4A) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataIC50:  390nMAssay Description:Inhibitory activity against Phosphodiesterase 4D (PDE4D) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50346088((1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphe...)
Affinity DataIC50:  410nMAssay Description:Inhibitory activity against Phosphodiesterase 4A (PDE4A) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(RAT)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50085143(CHEMBL158286 | Trifluoro-methanesulfonic acid 8-(3...)
Affinity DataIC50:  420nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(RAT)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50085145(CHEMBL161714 | Trifluoro-methanesulfonic acid 8-(3...)
Affinity DataIC50:  460nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(RAT)
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50085137(6-Furan-2-yl-8-(3-nitro-phenyl)-[1,7]naphthyridine...)
Affinity DataIC50:  510nMAssay Description:Inhibitory activity against Phosphodiesterase 4B (PDE4B) from rat source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50085139(4-[8-(3-Cyano-phenyl)-[1,7]naphthyridin-6-yl]-benz...)
Affinity DataIC50:  570nMAssay Description:Inhibitory activity against Phosphodiesterase 4C (PDE4C) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50085146(8-(3-Nitro-phenyl)-6-pyridin-3-yl-[1,7]naphthyridi...)
Affinity DataIC50:  610nMAssay Description:Inhibitory activity against Phosphodiesterase 4C (PDE4C) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Novartis Horsham Research Center

Curated by ChEMBL
LigandPNGBDBM50085143(CHEMBL158286 | Trifluoro-methanesulfonic acid 8-(3...)
Affinity DataIC50:  770nMAssay Description:Inhibitory activity against Phosphodiesterase 4A (PDE4A) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50346088((1r,4r)-4-cyano-4-(3-(cyclopentyloxy)-4-methoxyphe...)
Affinity DataIC50:  840nMAssay Description:Inhibitory activity against Phosphodiesterase 4C (PDE4C) from human source expressed in Saccharomyces cerevisiaeMore data for this Ligand-Target Pair
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