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Found 27 with Last Name = 'brayer' and Initial = 'gd'
TargetPancreatic alpha-amylase(Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM223314(YPYSCWARHVRIREN | piHA-D1)
Affinity DataKi:  1nMpH: 7.0Assay Description:The release of 2-chloro-4-nitrophenol resulting from the HPA-catalyzed hydrolysis of 2-chloro-4-nitrophenyl a-maltotrioside (CNPG3) was monitored at ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM223315(YPYSCWVRHSDPHKF | piHA-D3)
Affinity DataKi:  2.70nMpH: 7.0Assay Description:The release of 2-chloro-4-nitrophenol resulting from the HPA-catalyzed hydrolysis of 2-chloro-4-nitrophenyl a-maltotrioside (CNPG3) was monitored at ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM223316(YPYSCWVRH | piHA-Dm)
Affinity DataKi:  7nMpH: 7.0Assay Description:The release of 2-chloro-4-nitrophenol resulting from the HPA-catalyzed hydrolysis of 2-chloro-4-nitrophenyl a-maltotrioside (CNPG3) was monitored at ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM163646(Montbretin A (MbA))
Affinity DataKi:  8.10nM ΔG°:  -47.0kJ/moleT: 2°CAssay Description:Inhibitor concentrations varied from 0.25 to 5 times the Ki value in 50 mM sodium phosphate, 100 mM sodium chloride buffer, pH 7.0, at 30 °C. 2-Chlor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM163647(MbA-G (1))
Affinity DataKi:  9.10nM ΔG°:  -46.7kJ/moleT: 2°CAssay Description:Inhibitor concentrations varied from 0.25 to 5 times the Ki value in 50 mM sodium phosphate, 100 mM sodium chloride buffer, pH 7.0, at 30 °C. 2-Chlor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
University Of British Columbia

Curated by ChEMBL
LigandPNGBDBM50201794(CHEMBL3897445)
Affinity DataKi:  11nMAssay Description:Competitive inhibition of human recombinant cathepsin K using Z-FR-MCA fluorogenic substrate by Handerson plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM163648(MbA-R (2))
Affinity DataKi:  21.3nM ΔG°:  -44.5kJ/moleT: 2°CAssay Description:Inhibitor concentrations varied from 0.25 to 5 times the Ki value in 50 mM sodium phosphate, 100 mM sodium chloride buffer, pH 7.0, at 30 °C. 2-Chlor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
University Of British Columbia

Curated by ChEMBL
LigandPNGBDBM50201793(CHEMBL3899320)
Affinity DataKi:  41nMAssay Description:Competitive inhibition of human recombinant cathepsin K using Z-FR-MCA fluorogenic substrate by Handerson plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM163649(MbA-RX (3))
Affinity DataKi:  42.4nM ΔG°:  -42.8kJ/moleT: 2°CAssay Description:Inhibitor concentrations varied from 0.25 to 5 times the Ki value in 50 mM sodium phosphate, 100 mM sodium chloride buffer, pH 7.0, at 30 °C. 2-Chlor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM163650(MbA-GR (4))
Affinity DataKi:  79.3nM ΔG°:  -41.2kJ/moleT: 2°CAssay Description:Inhibitor concentrations varied from 0.25 to 5 times the Ki value in 50 mM sodium phosphate, 100 mM sodium chloride buffer, pH 7.0, at 30 °C. 2-Chlor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM163651(MbA-GRX (5) | mini-MbA)
Affinity DataKi:  93.3nM ΔG°:  -40.8kJ/moleT: 2°CAssay Description:Inhibitor concentrations varied from 0.25 to 5 times the Ki value in 50 mM sodium phosphate, 100 mM sodium chloride buffer, pH 7.0, at 30 °C. 2-Chlor...More data for this Ligand-Target Pair
TargetCathepsin K(Homo sapiens (Human))
University Of British Columbia

Curated by ChEMBL
LigandPNGBDBM50201793(CHEMBL3899320)
Affinity DataKi:  105nMAssay Description:Competitive inhibition of human recombinant cathepsin K using Z-FR-MCA fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
University Of British Columbia

Curated by ChEMBL
LigandPNGBDBM50201793(CHEMBL3899320)
Affinity DataKi:  105nMAssay Description:Competitive inhibition of human recombinant cathepsin K using Z-FR-MCA fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
University Of British Columbia

Curated by ChEMBL
LigandPNGBDBM50201795(CHEMBL3972383)
Affinity DataKi:  163nMAssay Description:Competitive inhibition of human recombinant cathepsin K using Z-FR-MCA fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrehalose synthase/amylase TreS(Mycobacterium tuberculosis)
University of British Columbia

LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataKi:  250nMAssay Description:The inhibition of TreS by a range of known alpha-glucosidase inhibitor was assayed.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
University Of British Columbia

Curated by ChEMBL
LigandPNGBDBM50201792(CHEMBL3942776)
Affinity DataKi:  393nMAssay Description:Competitive inhibition of human recombinant cathepsin K using Z-FR-MCA fluorogenic substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM163652(MbA-C (6))
Affinity DataKi:  730nM ΔG°:  -35.6kJ/moleT: 2°CAssay Description:Inhibitor concentrations varied from 0.25 to 5 times the Ki value in 50 mM sodium phosphate, 100 mM sodium chloride buffer, pH 7.0, at 30 °C. 2-Chlor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM163653(MbA-CG (7))
Affinity DataKi:  2.24E+3nM ΔG°:  -32.8kJ/moleT: 2°CAssay Description:Inhibitor concentrations varied from 0.25 to 5 times the Ki value in 50 mM sodium phosphate, 100 mM sodium chloride buffer, pH 7.0, at 30 °C. 2-Chlor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrehalose synthase/amylase TreS(Mycobacterium tuberculosis)
University of British Columbia

LigandPNGBDBM92460(Casuarine)
Affinity DataKi:  2.50E+3nMAssay Description:The inhibition of TreS by a range of known alpha-glucosidase inhibitor was assayed.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM163656(3-O-(6-(4-(Caffeamidomethyl)-triazolyl)hexyl)querc...)
Affinity DataKi:  1.39E+4nM ΔG°:  -28.2kJ/moleT: 2°CAssay Description:Inhibitor concentrations varied from 0.25 to 5 times the Ki value in 50 mM sodium phosphate, 100 mM sodium chloride buffer, pH 7.0, at 30 °C. 2-Chlor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM163654(MbA-CR (8))
Affinity DataKi:  4.68E+4nM ΔG°:  -25.1kJ/moleT: 2°CAssay Description:Inhibitor concentrations varied from 0.25 to 5 times the Ki value in 50 mM sodium phosphate, 100 mM sodium chloride buffer, pH 7.0, at 30 °C. 2-Chlor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM163655(MbA-CGR (9))
Affinity DataKi:  1.28E+5nM ΔG°:  -22.6kJ/moleT: 2°CAssay Description:Inhibitor concentrations varied from 0.25 to 5 times the Ki value in 50 mM sodium phosphate, 100 mM sodium chloride buffer, pH 7.0, at 30 °C. 2-Chlor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrehalose synthase/amylase TreS(Mycobacterium tuberculosis)
University of British Columbia

LigandPNGBDBM50182801((3R,4R,5R)-5-(Hydroxymethyl)piperidine-3,4-diol, 8...)
Affinity DataKi:  1.40E+5nMAssay Description:The inhibition of TreS by a range of known alpha-glucosidase inhibitor was assayed.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic alpha-amylase(Sus scrofa (Pig))
The University of Tokyo

LigandPNGBDBM223316(YPYSCWVRH | piHA-Dm)
Affinity DataIC50:  8.5nMpH: 7.0Assay Description:After kinetic analysis with HPA, piHA-Dm was tested as an inhibitor of ten additional enzymes. The conditions are listed as follows: Agrobacterium fa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-amylase 1A(Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM223316(YPYSCWVRH | piHA-Dm)
Affinity DataIC50:  34nMpH: 7.0Assay Description:After kinetic analysis with HPA, piHA-Dm was tested as an inhibitor of ten additional enzymes. The conditions are listed as follows: Agrobacterium fa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))
The University of Tokyo

LigandPNGBDBM223316(YPYSCWVRH | piHA-Dm)
Affinity DataIC50:  520nMpH: 7.0Assay Description:After kinetic analysis with HPA, piHA-Dm was tested as an inhibitor of ten additional enzymes. The conditions are listed as follows: Agrobacterium fa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSoluble maltase-glucoamylase(Mus musculus (Mouse))
The University of Tokyo

LigandPNGBDBM223316(YPYSCWVRH | piHA-Dm)
Affinity DataIC50:  990nMpH: 7.0Assay Description:After kinetic analysis with HPA, piHA-Dm was tested as an inhibitor of ten additional enzymes. The conditions are listed as follows: Agrobacterium fa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed