Compile Data Set for Download or QSAR
maximum 50k data
Found 32 with Last Name = 'brekken' and Initial = 'j'
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20787(2-amino-6-halopurine analogue, 26 | 6-chloro-9-[(2...)
Affinity DataEC50:  3.00E+3nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20815(2-amino-6-halopurine analogue, 37 | 6-chloro-9-[(3...)
Affinity DataEC50:  7.50E+3nMAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20789(2-amino-6-halopurine analogue, 18a | 6-chloro-9-[(...)
Affinity DataEC50:  50nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20790(2-amino-6-halopurine analogue, 18b | 9-[(2-bromo-3...)
Affinity DataEC50:  70nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20791(2-amino-6-halopurine analogue, 18c | 6-chloro-9-[(...)
Affinity DataEC50:  340nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20792(2-amino-6-halopurine analogue, 27 | 6-bromo-9-[(2-...)
Affinity DataEC50:  55nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20793(2-amino-6-halopurine analogue, 19a | 9-[(2-bromo-3...)
Affinity DataEC50:  1.70E+4nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20794(2-amino-6-halopurine analogue, 19b | 9-[(2-bromo-3...)
Affinity DataEC50:  4.50E+4nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20795(2-amino-6-halopurine analogue, 19c | 2-amino-9-[(2...)
Affinity DataEC50:  700nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20796(2-amino-6-halopurine analogue, 19d | 2-amino-9-[(2...)
Affinity DataEC50:  1.00E+5nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20797(2-amino-6-halopurine analogue, 19e | 9-[(2-bromo-3...)
Affinity DataEC50:  5.00E+4nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20798(2-amino-6-halopurine analogue, 19f | 9-[(2-chloro-...)
Affinity DataEC50:  1.80E+3nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM15359((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-...)
Affinity DataEC50:  7nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM15381(8-(2-chloro-3,4,5-trimethoxybenzyl)-2-fluoro-9-pen...)
Affinity DataEC50:  1.70E+3nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20753(9-{2-[(2,2-dimethylpropyl)amino]ethyl}-8-[(2-iodo-...)
Affinity DataEC50:  90nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20799(2-amino-6-halopurine analogue, 16 | 6-chloro-9-[(5...)
Affinity DataEC50:  20nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20800(2-amino-6-halopurine analogue, 20 | 6-chloro-9-[(4...)
Affinity DataEC50:  30nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20801(2-[(2-amino-6-chloro-9H-purin-9-yl)methyl]-3,5-dim...)
Affinity DataEC50:  1.00E+5nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20802(2-amino-6-halopurine analogue, 22 | 6-chloro-9-[(4...)
Affinity DataEC50:  1.50E+3nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20803(2-amino-6-halopurine analogue, 23 | 6-chloro-9-{[3...)
Affinity DataEC50:  1.50E+3nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20804(2-[(2-amino-6-chloro-9H-purin-9-yl)methyl]-4-metho...)
Affinity DataEC50:  80nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20805(2-amino-6-halopurine analogue, 25 | 6-chloro-9-[(6...)
Affinity DataEC50:  90nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20806(2-amino-6-halopurine analogue, 28 | 6-chloro-9-[(4...)
Affinity DataEC50:  38nMAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20807(2-amino-6-halopurine analogue, 29 | 9-[(4-bromo-3,...)
Affinity DataEC50:  15nMAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20808(2-amino-6-halopurine analogue, 30 | 6-chloro-9-[(4...)
Affinity DataEC50:  9nMAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20809(2-amino-6-halopurine analogue, 31 | 6-chloro-9-[(3...)
Affinity DataEC50:  1.00E+3nMAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20810(2-amino-6-halopurine analogue, 32 | 9-[(4-amino-3,...)
Affinity DataEC50:  5.80E+3nMAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20811(2-[(2-amino-6-chloro-9H-purin-9-yl)methyl]-3,5-dim...)
Affinity DataEC50:  990nMAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20812(2-amino-6-halopurine analogue, 34 | 6-chloro-9-[(3...)
Affinity DataEC50:  42nMAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20813(2-amino-6-halopurine analogue, 35 | 6-chloro-9-{[3...)
Affinity DataEC50:  27nMAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20814(2-amino-6-halopurine analogue, 36 | 6-chloro-9-[(4...)
Affinity DataEC50: >1.00E+4nMAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Biogen Idec

LigandPNGBDBM20788(2-amino-6-halopurine analogue, 17 | 6-chloro-9-[(3...)
Affinity DataEC50:  2.00E+3nMpH: 7.2 T: 2°CAssay Description:EC50 was defined as the concentration of the compound at which there was 50% degradation of the Her-2/neu protein in MCF7 breast carcinoma cells. Sam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed