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Found 186 with Last Name = 'bremberg' and Initial = 'u'
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50241539(CHEMBL4084845)
Affinity DataIC50:  37nMAssay Description:Kinetic constant was measured for PMII of Leishmania donovani promastigotes using supernatant (S12) fractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50262048(CHEMBL3134377)
Affinity DataIC50:  41nMAssay Description:Inhibition of recombinant human N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using histone H3(1-21)K4(Me1) biotin pe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50242934(CHEMBL4066743)
Affinity DataIC50:  50nMAssay Description:Inhibition of platelet aggregation (PRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50262023(CHEMBL4071991)
Affinity DataIC50:  57nMAssay Description:Inhibition of recombinant human N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using histone H3(1-21)K4(Me1) biotin pe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50242954(CHEMBL4101067)
Affinity DataIC50:  79nMAssay Description:Inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using Histone H3(1 to 21)K4(Me1) biotin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50241533(CHEMBL4102775)
Affinity DataIC50:  83nMAssay Description:Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50242894(CHEMBL4074323)
Affinity DataIC50:  83nMAssay Description:Inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using Histone H3(1 to 21)K4(Me1) biotin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM301063(4-{3-[((3R)-3- aminopiperidyl)carbonyl]-5-(2- pyri...)
Affinity DataIC50: <100nMAssay Description:Inhibition of full length human LSD1 expressed in Escherichia coli using H3K4me1-biotin labeled peptide as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50242895(CHEMBL4076163)
Affinity DataIC50:  150nMAssay Description:Inhibition of platelet aggregation (PRP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50242950(CHEMBL4074334)
Affinity DataIC50:  170nMAssay Description:Inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using Histone H3(1 to 21)K4(Me1) biotin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50242905(CHEMBL4103503)
Affinity DataIC50:  190nMAssay Description:Inhibition of Fibrinogen receptor bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50242892(CHEMBL4088045)
Affinity DataIC50:  200nMAssay Description:Inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using Histone H3(1 to 21)K4(Me1) biotin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50262052(CHEMBL4066130)
Affinity DataIC50:  210nMAssay Description:Inhibition of human ERG expressed in CHO cells by Ionworks electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50241526(CHEMBL4095018)
Affinity DataIC50:  210nMAssay Description:Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50242886(CHEMBL4104407)
Affinity DataIC50:  220nMAssay Description:Inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using Histone H3(1 to 21)K4(Me1) biotin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM301063(4-{3-[((3R)-3- aminopiperidyl)carbonyl]-5-(2- pyri...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using Histone H3(1 to 21)K4(Me1) biotin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50262070(CHEMBL4092760)
Affinity DataIC50:  260nMAssay Description:Inhibition of recombinant human N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using histone H3(1-21)K4(Me1) biotin pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50242952(CHEMBL4088035)
Affinity DataIC50:  270nMAssay Description:Ability to displace [3H]quipazine binding to 5-hydroxytryptamine 3 receptor sites in NG 108-15.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50241535(CHEMBL4068129)
Affinity DataIC50:  290nMAssay Description:Inhibitory activity against human immunodeficiency virus-1 reverse transcriptase(HIV-1 RT).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50242953(CHEMBL4066749)
Affinity DataIC50:  340nMAssay Description:Inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using Histone H3(1 to 21)K4(Me1) biotin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50241531(CHEMBL4095517)
Affinity DataIC50:  400nMAssay Description:Binding potency against Vasopressin V1 receptor in rat liver cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50242907(CHEMBL4077730)
Affinity DataIC50:  410nMAssay Description:Inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using Histone H3(1 to 21)K4(Me1) biotin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50242905(CHEMBL4103503)
Affinity DataIC50:  420nMAssay Description:Inhibition of LSD1 in human THP1 cells assessed as upregulation of CD86 levels by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50241520(CHEMBL4064882)
Affinity DataIC50:  430nMAssay Description:Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50242934(CHEMBL4066743)
Affinity DataIC50:  480nMAssay Description:Inhibition of Fibrinogen receptor bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50242883(CHEMBL4062785)
Affinity DataIC50:  510nMAssay Description:Inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using Histone H3(1 to 21)K4(Me1) biotin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50242954(CHEMBL4101067)
Affinity DataIC50:  520nMAssay Description:Inhibition of LSD1 in human THP1 cells assessed as upregulation of CD86 levels by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50262045(CHEMBL4087724)
Affinity DataIC50:  570nMAssay Description:Inhibition of recombinant human N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using histone H3(1-21)K4(Me1) biotin pe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50241493(CHEMBL4103264)
Affinity DataIC50:  620nMAssay Description:Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50242891(CHEMBL4095768)
Affinity DataIC50:  650nMAssay Description:Inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using Histone H3(1 to 21)K4(Me1) biotin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50242890(CHEMBL4077739)
Affinity DataIC50:  670nMAssay Description:Inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using Histone H3(1 to 21)K4(Me1) biotin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50262071(CHEMBL4100487)
Affinity DataIC50:  680nMAssay Description:Binding affinity to LSD1 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50242948(CHEMBL4082935)
Affinity DataIC50:  710nMAssay Description:Inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using Histone H3(1 to 21)K4(Me1) biotin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50242889(CHEMBL4069461)
Affinity DataIC50:  720nMAssay Description:Inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using Histone H3(1 to 21)K4(Me1) biotin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50242956(CHEMBL4085581)
Affinity DataIC50:  750nMAssay Description:Inhibition of Fibrinogen receptor bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50241495(CHEMBL4079933)
Affinity DataIC50:  810nMAssay Description:Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50262044(CHEMBL4082476)
Affinity DataIC50:  820nMAssay Description:Inhibition of recombinant human N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using histone H3(1-21)K4(Me1) biotin pe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50241534(CHEMBL4074550)
Affinity DataIC50:  830nMAssay Description:Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50262074(CHEMBL4105603)
Affinity DataIC50:  950nMAssay Description:Inhibition of recombinant human N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using histone H3(1-21)K4(Me1) biotin pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50241523(CHEMBL4084823)
Affinity DataIC50:  990nMAssay Description:Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50241527(CHEMBL4098894)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50242951(CHEMBL4096682)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using Histone H3(1 to 21)K4(Me1) biotin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50262072(CHEMBL4079770)
Affinity DataIC50:  1.20E+3nMAssay Description:Binding affinity to LSD1 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50242896(CHEMBL4093330)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using Histone H3(1 to 21)K4(Me1) biotin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50242887(CHEMBL4080173)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using Histone H3(1 to 21)K4(Me1) biotin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50241497(CHEMBL4087810)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50241528(CHEMBL4071901)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50242885(CHEMBL4101077)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using Histone H3(1 to 21)K4(Me1) biotin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50242945(CHEMBL4073624)
Affinity DataIC50:  1.50E+3nMAssay Description:Binding affinity against adenosine A1 receptor using [3H]-CHA or [3H]PIA as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50241519(CHEMBL4073481)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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