TargetMelatonin receptor type 1A(Homo sapiens (Human))
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 0.0230nMAssay Description:Inhibition of specific binding of [3H]-BK (1 nM) to rat Bradykinin receptor B2 by 50% in NG108-15 cell membranesMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
TargetMelatonin receptor type 1A(GUINEA PIG)
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
TargetMelatonin receptor type 1A(GUINEA PIG)
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
TargetMelatonin receptor type 1A(GUINEA PIG)
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 0.100nMAssay Description:Antagonist activity at human recombinant histamine H1 receptor expressed in intact CHO cells assessed as inhibition of histamine-induced cellular cal...More data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(GUINEA PIG)
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 0.158nMAssay Description:Antagonist activity at human recombinant histamine H1 receptor expressed in intact CHO cells assessed as inhibition of histamine-induced cellular cal...More data for this Ligand-Target Pair
Affinity DataKi: 0.158nMAssay Description:Antagonist activity at human recombinant histamine H1 receptor expressed in intact CHO cells assessed as inhibition of histamine-induced cellular cal...More data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 0.162nMAssay Description:Antagonist activity at human H1 receptor expressed in CHO cells assessed as inhibition of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 0.200nMAssay Description:Antagonist activity at human recombinant histamine H1 receptor expressed in intact CHO cells assessed as inhibition of histamine-induced cellular cal...More data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(GUINEA PIG)
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
TargetMelatonin receptor type 1A(GUINEA PIG)
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 0.251nMAssay Description:Antagonist activity at human H1 receptor expressed in CHO cells assessed as inhibition of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Antagonist activity at human recombinant histamine H1 receptor expressed in intact CHO cells assessed as inhibition of histamine-induced cellular cal...More data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Antagonist activity at human recombinant histamine H1 receptor expressed in intact CHO cells assessed as inhibition of histamine-induced cellular cal...More data for this Ligand-Target Pair
Affinity DataKi: 0.251nMAssay Description:Antagonist activity at human H3 receptor expressed in CHO cells assessed as inhibition of histamine-induced GTPgamma[S] binding by scintillation prox...More data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Inhibition of specific binding of [3H]-BK (1 nM) to rat Bradykinin receptor B2 by 50% in NG108-15 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Antagonist activity at human recombinant histamine H1 receptor expressed in intact CHO cells assessed as inhibition of histamine-induced cellular cal...More data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Antagonist activity at human recombinant histamine H1 receptor expressed in intact CHO cells assessed as inhibition of histamine-induced cellular cal...More data for this Ligand-Target Pair
Affinity DataKi: 0.316nMAssay Description:Antagonist activity at human H1 receptor expressed in CHO cells assessed as inhibition of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(GUINEA PIG)
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 0.347nMAssay Description:Antagonist activity at human H1 receptor expressed in CHO cells assessed as inhibition of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
Syntex Research
Curated by ChEMBL
Syntex Research
Curated by ChEMBL
Affinity DataKi: 0.355nMAssay Description:Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membraneMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
Syntex Research
Curated by ChEMBL
Syntex Research
Curated by ChEMBL
Affinity DataKi: 0.355nMAssay Description:In vitro inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
Affinity DataKi: 0.355nMAssay Description:Antagonist activity at human H1 receptor expressed in CHO cells assessed as inhibition of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 0.398nMAssay Description:Antagonist activity at human H1 receptor expressed in CHO cells assessed as inhibition of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Vanderbilt University School Of Medicine
Curated by ChEMBL
Vanderbilt University School Of Medicine
Curated by ChEMBL
Affinity DataKi: 0.454nMAssay Description:Binding affinity to GST-tagged Mcl-1 (unknown origin) incubated for 60 mins by TR-FRET-binding affinity assayMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
Syntex Research
Curated by ChEMBL
Syntex Research
Curated by ChEMBL
Affinity DataKi: 0.457nMAssay Description:Binding affinity to alpha-2 adrenergic receptor determined by measurement of [3H]yohimbine displacement from rat cortical membraneMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(GUINEA PIG)
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 0.5nMAssay Description:Inhibition of specific binding of [3H]-BK (1 nM) to rat Bradykinin receptor B2 by 50% in NG108-15 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of binding of [3H]-BK to rat bradykinin B2 receptor expressed in NG108-15 neuroblastoma-glioma hybrid cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Antagonist activity at human recombinant histamine H1 receptor expressed in intact CHO cells assessed as inhibition of histamine-induced cellular cal...More data for this Ligand-Target Pair
Affinity DataKi: 0.513nMAssay Description:Antagonist activity at human H1 receptor expressed in CHO cells assessed as inhibition of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.537nMAssay Description:Antagonist activity at human H1 receptor expressed in CHO cells assessed as inhibition of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Glaxo Wellcome Research and Development
Curated by PDSP Ki Database
Affinity DataKi: 0.562nMAssay Description:Antagonist activity at human H3 receptor expressed in CHO cells assessed as inhibition of histamine-induced GTPgamma[S] binding by scintillation prox...More data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of specific binding of [3H]-BK (1 nM) to rat Bradykinin receptor B2 by 50% in NG108-15 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of binding of [3H]-BK to rat bradykinin B2 receptor expressed in NG108-15 neuroblastoma-glioma hybrid cell membranesMore data for this Ligand-Target Pair