Reaction Details Report a problem with these data
Target
Melatonin receptor type 1A
Ligand
BDBM85064
Substrate
n/a
Ki
0.14±n/a nM
Comments
PDSP_886
Citation
 Beresford, IJ; Browning, C; Starkey, SJ; Brown, J; Foord, SM; Coughlan, J; North, PC; Dubocovich, ML; Hagan, RM GR196429: a nonindolic agonist at high-affinity melatonin receptors. J Pharmacol Exp Ther 285:1239-45 (1998) [PubMed] 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Homo sapiens (Human)
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM85064
Synonyms:
CAS_5311134 | GR 196429 | NSC_5311134
Type:
Small organic molecule
Emp. Form.:
C14H18N2O2
Mol. Mass.:
246.3049
SMILES:
CC(=O)NCCN1CCc2ccc3OCCc3c12
Structure:
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