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Found 217 with Last Name = 'brunetti' and Initial = 't'
TargetHistone deacetylase 6(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human HDAC6More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM50297445(CHEMBL561483 | N-hydroxy-7,7-bis(7-methoxy-1H-indo...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of human HDAC6 by fluroimetryChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM50007730(CHEMBL3233755)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of human HDAC-6 using RHKK(Ac) as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361691(CHEMBL1940934)
Affinity DataIC50:  5.40nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM50297444(CHEMBL564876 | N-hydroxy-7,7-di(1H-indol-3-yl)hept...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human HDAC6 by fluroimetryChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human HDAC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361698(CHEMBL1941047)
Affinity DataIC50:  7.40nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361693(CHEMBL1938422)
Affinity DataIC50:  8.60nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361700(CHEMBL1941049)
Affinity DataIC50:  8.80nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361719(CHEMBL1941068)
Affinity DataIC50:  10nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human HDAC3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361697(CHEMBL1940949)
Affinity DataIC50:  12nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human HDAC4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361695(CHEMBL1940944)
Affinity DataIC50:  12.6nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361733(CHEMBL1940943)
Affinity DataIC50:  14nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361696(CHEMBL1940947)
Affinity DataIC50:  15nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361727(CHEMBL1941076)
Affinity DataIC50:  15nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human HDAC11More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 5(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human HDAC5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM50297446(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human HDAC3 by fluroimetryChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361713(CHEMBL1941062)
Affinity DataIC50:  19nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361699(CHEMBL1941048)
Affinity DataIC50:  19.6nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human HDAC10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361726(CHEMBL1941075)
Affinity DataIC50:  20nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361712(CHEMBL1941061)
Affinity DataIC50:  20nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM50297446(CHEMBL561604 | N-hydroxy-7,7-bis(5-nitro-1H-indol-...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human HDAC6 by fluroimetryChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361715(CHEMBL1941064)
Affinity DataIC50:  22nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361710(CHEMBL1941059)
Affinity DataIC50:  22nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human HDAC7More data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM50297445(CHEMBL561483 | N-hydroxy-7,7-bis(7-methoxy-1H-indo...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human HDAC3 by fluroimetryChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human HDAC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361687(CHEMBL1940930)
Affinity DataIC50:  24nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361711(CHEMBL1941060)
Affinity DataIC50:  24nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361707(CHEMBL1941056)
Affinity DataIC50:  24nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361692(CHEMBL1940940)
Affinity DataIC50:  24nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361703(CHEMBL1941052)
Affinity DataIC50:  26nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361717(CHEMBL1941066)
Affinity DataIC50:  27nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361689(CHEMBL1940932)
Affinity DataIC50:  28nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007729(CHEMBL3233488)
Affinity DataIC50:  29nMAssay Description:Displacement of GM-FTC from Hsp90-alpha (unknown origin) after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
R&D Sigma-Tau

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human HDAC-6 using RHKK(Ac) as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361688(CHEMBL1940931)
Affinity DataIC50:  30nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361709(CHEMBL1941058)
Affinity DataIC50:  32nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361708(CHEMBL1941057)
Affinity DataIC50:  32nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007730(CHEMBL3233755)
Affinity DataIC50:  33nMAssay Description:Displacement of GM-FTC from Hsp90-alpha (unknown origin) after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361724(CHEMBL1941073)
Affinity DataIC50:  33nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361705(CHEMBL1941054)
Affinity DataIC50:  34nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361704(CHEMBL1941053)
Affinity DataIC50:  34nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361725(CHEMBL1941074)
Affinity DataIC50:  34nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50007731(CHEMBL3233754)
Affinity DataIC50:  34nMAssay Description:Displacement of GM-FTC from Hsp90-alpha (unknown origin) after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50361720(CHEMBL1941069)
Affinity DataIC50:  36nMAssay Description:Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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