TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 0.380nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 0.410nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 0.640nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 0.660nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 1.05nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 1.26nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 8.17nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 8.95nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 9.31nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 10.9nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 12.8nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 15.8nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 19.1nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 19.1nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 23.1nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 31.9nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 32.2nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 47.7nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of human ErbB4 tyrosine kinase phosphorylation expressed in human CEM/4 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: >50nMAssay Description:Inhibition of human EGFR tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of human ErbB4 tyrosine kinase phosphorylation expressed in human CEM/4 cellsMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Displacement of [125I]4-(3-iodoanilino)-6,7-dimethoxyquinazoline from EGFR tyrosine kinase in human A431 cell membranesMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Inhibition of human ErbB4 tyrosine kinase phosphorylation expressed in human CEM/4 cellsMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Inhibition of human ErbB2 tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: >100nMAssay Description:Inhibition of human ErbB4 tyrosine kinase phosphorylation expressed in human CEM/4 cellsMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 143nMAssay Description:Inhibition of human ErbB2 tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 215nMAssay Description:Inhibition of human ErbB2 tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Lawrence Berkeley National Laboratory
Curated by ChEMBL
Affinity DataIC50: 231nMAssay Description:Inhibition of human ErbB2 tyrosine kinase phosphorylation expressed in mouse BaF3 cellsMore data for this Ligand-Target Pair