TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Binding affinity to human recombinant BHMT expressed in Escherichia coli using variable levels of betaine substrate by Dixon plotMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Inhibition of human recombinant thymidine phosphorylaseMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 236nMAssay Description:Inhibition of human recombinant thymidine phosphorylaseMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 236nMAssay Description:Inhibition of human recombinant thymidine phosphorylaseMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 236nMAssay Description:Inhibition of human recombinant thymidine phosphorylaseMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 236nMAssay Description:Inhibition of human recombinant thymidine phosphorylaseMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 236nMAssay Description:Inhibition of human recombinant thymidine phosphorylaseMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 236nMAssay Description:Inhibition of human recombinant thymidine phosphorylaseMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Rattus norvegicus)
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Rattus norvegicus)
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Rattus norvegicus)
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Rattus norvegicus)
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:Inhibition of human recombinant BHMT expressed in Escherichia coli using 2 mM betaine and 1 mM DL-homocysteine as substrateMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of human recombinant BHMT expressed in Escherichia coli using 2 mM betaine and 1 mM DL-homocysteine as substrateMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 138nMAssay Description:Inhibition of human recombinant BHMT expressed in Escherichia coli using 2 mM betaine and 1 mM DL-homocysteine as substrateMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 139nMAssay Description:Inhibition of human recombinant BHMT expressed in Escherichia coli using 2 mM betaine and 1 mM DL-homocysteine as substrateMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Rattus norvegicus)
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Rattus norvegicus)
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Rattus norvegicus)
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Rattus norvegicus)
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Rattus norvegicus)
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 649nMAssay Description:Inhibition of human recombinant BHMT expressed in Escherichia coli using 2 mM betaine and 1 mM DL-homocysteine as substrateMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 701nMAssay Description:Inhibition of human recombinant BHMT expressed in Escherichia coli using 2 mM betaine and 1 mM DL-homocysteine as substrateMore data for this Ligand-Target Pair
TargetThymidine phosphorylase(Rattus norvegicus)
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibition of thymidine phosphorylase in T cell lymphomas of Sprague-Dawley rat in presence of 100 uM thymidine and 200 uM phosphateMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(RAT)
Institute Of Pharmacy And Biochemistry
Curated by ChEMBL
Institute Of Pharmacy And Biochemistry
Curated by ChEMBL
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of binding of [3H]-quinuclidinyl benzilate to Muscarinic acetylcholine receptor M1 in rat brain cortex at 10e-5 M of compound concentratio...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M1(RAT)
Institute Of Pharmacy And Biochemistry
Curated by ChEMBL
Institute Of Pharmacy And Biochemistry
Curated by ChEMBL
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of binding of [3H]-quinuclidinyl benzilate to Muscarinic acetylcholine receptor M1 in rat brain cortex at 10e-5 M of compound concentratio...More data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant BHMT expressed in Escherichia coli using 2 mM betaine and 1 mM DL-homocysteine as substrateMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rattus norvegicus (Rat))
Institute Of Pharmacy And Biochemistry
Curated by ChEMBL
Institute Of Pharmacy And Biochemistry
Curated by ChEMBL
Affinity DataIC50: 2.69E+3nMAssay Description:Inhibition of [3H]-5-HT binding to 5-hydroxytryptamine 1B receptor in rat striatum; Residual radioligand binding higher than 50%More data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 3.26E+3nMAssay Description:Inhibition of human recombinant BHMT expressed in Escherichia coli using 2 mM betaine and 1 mM DL-homocysteine as substrateMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(RAT)
Institute Of Pharmacy And Biochemistry
Curated by ChEMBL
Institute Of Pharmacy And Biochemistry
Curated by ChEMBL
Affinity DataIC50: 3.51E+3nMAssay Description:Inhibition of binding of [3H]-quinuclidinyl benzilate to Muscarinic acetylcholine receptor M2 in rat heart atria at 10e-5 M of compound concentrationMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M2(RAT)
Institute Of Pharmacy And Biochemistry
Curated by ChEMBL
Institute Of Pharmacy And Biochemistry
Curated by ChEMBL
Affinity DataIC50: 4.18E+3nMAssay Description:Inhibition of binding of [3H]-quinuclidinyl benzilate to Muscarinic acetylcholine receptor M2 in rat heart atria at 10e-5 M of compound concentrationMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Institute Of Pharmacy And Biochemistry
Curated by ChEMBL
Institute Of Pharmacy And Biochemistry
Curated by ChEMBL
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of [3H]-8-hydroxy-2-dipropylamino-1,2,3,4-tetrahydronaphthalene binding to 5-hydroxytryptamine 1A receptor in hippocampus region of rat br...More data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKd: 83nMAssay Description:Binding affinity to human recombinant BHMT expressed in Escherichia coli by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetBetaine--homocysteine S-methyltransferase 1(Homo sapiens (Human))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKd: 280nMAssay Description:Binding affinity to human recombinant BHMT expressed in Escherichia coli by intrinsic tryptophan fluorescence studiesMore data for this Ligand-Target Pair