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Target
Muscarinic acetylcholine receptor M2
Ligand
BDBM50084051
Substrate
n/a
Meas. Tech.
ChEBML_140050
IC50
4180±n/a nM
Citation
 Rádl, S; Hezký, P; Hafner, W; Budesínský, M; Hejnová, L Synthesis and binding studies of some epibatidine analogues. Bioorg Med Chem Lett 10:55-8 (2000) [PubMed]  Article 
Target
Name:
Muscarinic acetylcholine receptor M2
Synonyms:
ACM2_RAT | Cholinergic, muscarinic M2 | Chrm-2 | Chrm2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51555.53
Organism:
RAT
Description:
P10980
Residue:
466
Sequence:
MNNSTNSSNNGLAITSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKEKKEPVANQDPVSPSLVQGRIVKPNNNNMPGGDGGLEHNKIQNGKAPRDGVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSRDDNSKQTCIKIVTKAQKGDVCTPTSTTVELVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR
  
Inhibitor
Name:
BDBM50084051
Synonyms:
3-(6-Chloro-pyridin-3-yl)-8-methyl-8-aza-bicyclo[3.2.1]oct-2-ene; compound with (Z)-but-2-enedioic acid | CHEMBL345233
Type:
Small organic molecule
Emp. Form.:
C13H15ClN2
Mol. Mass.:
234.725
SMILES:
CN1C2CCC1C=C(C2)c1ccc(Cl)nc1 |c:7,THB:9:7:1:4.3|
Structure:
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