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Found 27 with Last Name = 'burke' and Initial = 'pj'
TargetCarboxypeptidase G2(Pseudomonas aeruginosa)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50074672((R)-2-(4-Methoxy-phenylsulfanylcarbonylamino)-pent...)
Affinity DataKi:  300nMAssay Description:Inhibitory activity against bacterial carboxypeptidase G2 by Dixon plot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase G2(Pseudomonas aeruginosa)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50074680(2-p-Tolylsulfanylcarbonylamino-pentanedioic acid |...)
Affinity DataKi:  1.05E+3nMAssay Description:Inhibitory activity against bacterial carboxypeptidase G2 by Dixon plot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase G2(Pseudomonas aeruginosa)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50074674(2-(3-Methoxy-phenylsulfanylcarbonylamino)-pentaned...)
Affinity DataKi:  1.07E+3nMAssay Description:Inhibitory activity against bacterial carboxypeptidase G2 by Dixon plot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase G2(Pseudomonas aeruginosa)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50074673(2-(3-Amino-phenylsulfanylcarbonylamino)-pentanedio...)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibitory activity against bacterial carboxypeptidase G2 by Dixon plot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase G2(Pseudomonas aeruginosa)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50074679(2-(4-Amino-phenylsulfanylcarbonylamino)-pentanedio...)
Affinity DataKi:  5.80E+3nMAssay Description:Inhibitory activity against bacterial carboxypeptidase G2 by Dixon plot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase G2(Pseudomonas aeruginosa)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50074678(2-(1-Oxy-pyridin-4-ylsulfanylcarbonylamino)-pentan...)
Affinity DataKi:  1.65E+5nMAssay Description:Inhibitory activity against bacterial carboxypeptidase G2 by Dixon plot assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
University Of Colorado

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysateMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
University Of Colorado

Curated by ChEMBL
LigandPNGBDBM50474781(CHEMBL19195)
Affinity DataIC50:  5nMAssay Description:Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
University Of Colorado

Curated by ChEMBL
LigandPNGBDBM50411320(CHEMBL222694)
Affinity DataIC50:  30nMAssay Description:Growth inhibition of MDA-MB-231 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
University Of Colorado

Curated by ChEMBL
LigandPNGBDBM50411320(CHEMBL222694)
Affinity DataIC50:  30nMAssay Description:Growth inhibition of MCF7 cells expressing ER and antiestrogen binding sitesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
University Of Colorado

Curated by ChEMBL
LigandPNGBDBM50411320(CHEMBL222694)
Affinity DataIC50:  40nMAssay Description:Growth inhibition of MDA-MB-435 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
University Of Colorado

Curated by ChEMBL
LigandPNGBDBM50411319(CHEMBL266892)
Affinity DataIC50:  50nMAssay Description:Growth inhibition of MDA-MB-435 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
University Of Colorado

Curated by ChEMBL
LigandPNGBDBM50411320(CHEMBL222694)
Affinity DataIC50:  60nMAssay Description:Growth inhibition of multidrug resistant MCF7/Adr cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
University Of Colorado

Curated by ChEMBL
LigandPNGBDBM50411319(CHEMBL266892)
Affinity DataIC50:  70nMAssay Description:Growth inhibition of MCF7 cells expressing ER and antiestrogen binding sitesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
University Of Colorado

Curated by ChEMBL
LigandPNGBDBM50411319(CHEMBL266892)
Affinity DataIC50:  80nMAssay Description:Growth inhibition of MDA-MB-231 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
University Of Colorado

Curated by ChEMBL
LigandPNGBDBM50474779(CHEMBL19481)
Affinity DataIC50:  150nMAssay Description:Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
University Of Colorado

Curated by ChEMBL
LigandPNGBDBM50474783(CHEMBL278308)
Affinity DataIC50:  150nMAssay Description:Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
University Of Colorado

Curated by ChEMBL
LigandPNGBDBM22984((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...)
Affinity DataIC50:  150nMAssay Description:Growth inhibition of MDA-MB-435 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
University Of Colorado

Curated by ChEMBL
LigandPNGBDBM22984((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...)
Affinity DataIC50:  200nMAssay Description:Growth inhibition of MCF7 cells expressing ER and antiestrogen binding sitesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
University Of Colorado

Curated by ChEMBL
LigandPNGBDBM50474784(CHEMBL410193)
Affinity DataIC50:  200nMAssay Description:Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
University Of Colorado

Curated by ChEMBL
LigandPNGBDBM22984((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...)
Affinity DataIC50:  300nMAssay Description:Growth inhibition of MDA-MB-231 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
University Of Colorado

Curated by ChEMBL
LigandPNGBDBM50474780(CHEMBL266703)
Affinity DataIC50:  300nMAssay Description:Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
University Of Colorado

Curated by ChEMBL
LigandPNGBDBM50474785(CHEMBL266185)
Affinity DataIC50:  300nMAssay Description:Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
University Of Colorado

Curated by ChEMBL
LigandPNGBDBM50474782(CHEMBL19535)
Affinity DataIC50:  300nMAssay Description:Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
University Of Colorado

Curated by ChEMBL
LigandPNGBDBM50411319(CHEMBL266892)
Affinity DataIC50:  2.00E+3nMAssay Description:Growth inhibition of multidrug resistant MCF7/Adr cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
University Of Colorado

Curated by ChEMBL
LigandPNGBDBM20607((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of [3H]E2 binding to estrogen receptor alpha in MCF-7 cell lysateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target7-dehydrocholesterol reductase(Homo sapiens (Human))
University Of Colorado

Curated by ChEMBL
LigandPNGBDBM22984((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...)
Affinity DataIC50:  1.00E+4nMAssay Description:Growth inhibition of multidrug resistant MCF7/Adr cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed