Reaction Details Report a problem with these data
Target
Carboxypeptidase G2
Ligand
BDBM50074680
Substrate
n/a
Meas. Tech.
ChEMBL_45646 (CHEMBL873194)
Ki
1050±n/a nM
Citation
 Khan, TH; Eno-Amooquaye, EA; Searle, F; Browne, PJ; Osborn, HM; Burke, PJ Novel inhibitors of carboxypeptidase G2 (CPG2): potential use in antibody-directed enzyme prodrug therapy. J Med Chem 42:951-6 (1999) [PubMed]  Article 
Target
Name:
Carboxypeptidase G2
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
44005.37
Organism:
Pseudomonas aeruginosa
Description:
ChEMBL_302801
Residue:
412
Sequence:
MHARRLPRLLPLALAFLLSPAAFAADTPAAELLRQAEAERPAYLDTLRQLVAVDSGTGQAEGLGQLSALLAERLQALGAQVRSAPATPSAGDNLVATLDGTGSKRFLLMIHYDTVFAAGSAAKRPFREDAERAYGPGVADAKGGVAMVLHALALLRQQGFRDYGRITVLFNPDEETGSAGSKQLIAELARQQDYVFSYEPPDRDAVTVATNGIDGLLLEVKGRSSHAGSAPEQGRNAILELSHQLLRLKDLGDPAKGTTLNWTLARGGEKRNIIPAEASAEADMRYSDPAESERVLADARKLTGERLVADTEVSLRLDKGRPPLVKNPASQRLAETAQTLYGRIGKRIEPIAMRFGTDAGYAYVPGSDKPAVLETLGVVGAGLHSEAEYLELSSIAPRLYLTVALIRELSAD
  
Inhibitor
Name:
BDBM50074680
Synonyms:
2-p-Tolylsulfanylcarbonylamino-pentanedioic acid | CHEMBL172027
Type:
Small organic molecule
Emp. Form.:
C13H15NO5S
Mol. Mass.:
297.327
SMILES:
Cc1ccc(SC(=O)NC(CCC(O)=O)C(O)=O)cc1
Structure:
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