TargetProstaglandin E synthase(Homo sapiens (Human))
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 16.5nMAssay Description:Inhibition of human recombinant mPGES-1More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant soluble epoxide hydrolase using PHOME as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant soluble epoxide hydrolase using PHOME as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of 5-lipoxygenase in S100 cell free fraction of human polymorphonuclear leukocytes assessed as reduction in 5-LO product formation preincu...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in Escherichia coli using 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methylester-2-o...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in Escherichia coli using 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methylester-2-o...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in Escherichia coli using 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methylester-2-o...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in Escherichia coli using 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methylester-2-o...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of recombinant soluble epoxide hydrolase using PHOME as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of 5-lipoxygenase in S100 cell free fraction of human polymorphonuclear leukocytes assessed as reduction in 5-LO product formation preincu...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in Escherichia coli using 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methylester-2-o...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant soluble epoxide hydrolase using PHOME as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in Escherichia coli using 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methylester-2-o...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant soluble epoxide hydrolase using PHOME as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of 5-lipoxygenase in S100 cell free fraction of human polymorphonuclear leukocytes assessed as reduction in 5-LO product formation preincu...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of 5-lipoxygenase in S100 cell free fraction of human polymorphonuclear leukocytes assessed as reduction in 5-LO product formation preincu...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in Escherichia coli using 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methylester-2-o...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in Escherichia coli using 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methylester-2-o...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of 5-lipoxygenase in S100 cell free fraction of human polymorphonuclear leukocytes assessed as reduction in 5-LO product formation preincu...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of 5-lipoxygenase in S100 cell free fraction of human polymorphonuclear leukocytes assessed as reduction in 5-LO product formation preincu...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in Escherichia coli using 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methylester-2-o...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in Escherichia coli using 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methylester-2-o...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 65nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in Escherichia coli using 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methylester-2-o...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in Escherichia coli using 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methylester-2-o...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in Escherichia coli using 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methylester-2-o...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in Escherichia coli using 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methylester-2-o...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of recombinant soluble epoxide hydrolase using PHOME as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of 5-lipoxygenase in S100 cell free fraction of human polymorphonuclear leukocytes assessed as reduction in 5-LO product formation preincu...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of 5-lipoxygenase in human polymorphonuclear leukocytes assessed as reduction in A23187 and AA-stimulated 5-LO product formation preincuba...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of 5-lipoxygenase in S100 cell free fraction of human polymorphonuclear leukocytes assessed as reduction in 5-LO product formation preincu...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 82nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in Escherichia coli using 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methylester-2-o...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 87nMAssay Description:Inhibition of recombinant soluble epoxide hydrolase using PHOME as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in Escherichia coli using 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methylester-2-o...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in Escherichia coli using 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methylester-2-o...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of 5-lipoxygenase in S100 cell free fraction of human polymorphonuclear leukocytes assessed as reduction in 5-LO product formation preincu...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of 5-lipoxygenase in human polymorphonuclear leukocytes assessed as reduction in A23187 and AA-stimulated 5-LO product formation preincuba...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 104nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in Escherichia coli using 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methylester-2-o...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 106nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in Escherichia coli using 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methylester-2-o...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 107nMAssay Description:Inhibition of recombinant soluble epoxide hydrolase using PHOME as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 107nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 116nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of mPGES-1 derived from IL1beta and TNFalpha stimulated human HeLa cells microsomal fraction using PGH2 as substrate preincubated for 30 m...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of 5-lipoxygenase in human polymorphonuclear leukocytes assessed as reduction in A23187 and AA-stimulated 5-LO product formation preincuba...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 147nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in Escherichia coli using 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methylester-2-o...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of 5-lipoxygenase in human polymorphonuclear leukocytes assessed as reduction in A23187 and AA-stimulated 5-LO product formation preincuba...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of 5-lipoxygenase in human polymorphonuclear leukocytes assessed as reduction in A23187 and AA-stimulated 5-LO product formation preincuba...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of 5-lipoxygenase in human polymorphonuclear leukocytes assessed as reduction in A23187 and AA-stimulated 5-LO product formation preincuba...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Zafes/Liff/Osf Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 178nMAssay Description:Inhibition of recombinant soluble epoxide hydrolase using PHOME as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of mPGES-1 derived from IL1beta and TNFalpha stimulated human HeLa cells microsomal fraction using PGH2 as substrate preincubated for 30 m...More data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
Johann Wolfgang Goethe University
Curated by ChEMBL
Johann Wolfgang Goethe University
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of mPGES-1 derived from IL1beta and TNFalpha stimulated human HeLa cells microsomal fraction using PGH2 as substrate preincubated for 30 m...More data for this Ligand-Target Pair