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Found 84 with Last Name = 'bush' and Initial = 'rc'
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50033969(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Affinity DataIC50:  10nMAssay Description:Concentration required for the inhibition of Cholesterol O-acyl transferase from HepG2 microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280419(2-[3-(1-Methyl-1H-imidazole-2-sulfonyl)-propylsulf...)
Affinity DataIC50:  11nMAssay Description:Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Cricetulus griseus)
TBA

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  12nMAssay Description:Concentration required for the inhibition of Cholesterol O-acyl transferase from hamster liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280416(2-[3-(1-Methyl-1H-imidazol-2-ylsulfanyl)-propylsul...)
Affinity DataIC50:  14nMAssay Description:Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280422(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  24nMAssay Description:Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  25nMAssay Description:Compound was evaluated for inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in microsomes from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  25nMAssay Description:Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003845(6-(4,5-Diphenyl-1H-imidazol-2-ylsulfanylmethyl)-2-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  35nMAssay Description:Concentration required for the inhibition of Cholesterol O-acyl transferase from cholesterol fed rabbit gutMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280418(2-[4-(1-Methyl-1H-imidazol-2-ylsulfanyl)-butylsulf...)
Affinity DataIC50:  38nMAssay Description:Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  40nMAssay Description:Compound was evaluated for inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in microsomes from rabbit artery.More data for this Ligand-Target Pair
In DepthDetails Article
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  40nMAssay Description:Concentration required for the inhibition of Cholesterol O-acyl transferase from pig liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  40nMAssay Description:Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  43nMAssay Description:Concentration required for the inhibition of rabbit arterial Acyl coenzyme A:cholesterol acyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  44nMAssay Description:Concentration required for the inhibition of Cholesterol O-acyl transferase from marmoset gutMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280421(2-[5-(1H-Imidazol-2-ylsulfanyl)-pentylsulfanyl]-4,...)
Affinity DataIC50:  44nMAssay Description:Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  44nMAssay Description:Compound was evaluated for inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in microsomes from rabbit liver.More data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  45nMAssay Description:Concentration required for the inhibition of ACAT from rat gutMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003811(2-(3-[1,3]Dioxan-2-yl-propylsulfanyl)-4,5-diphenyl...)
Affinity DataIC50:  47nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280420(1-[6-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-hexyl...)
Affinity DataIC50:  48nMAssay Description:Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280417(1-[3-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-propy...)
Affinity DataIC50:  50nMAssay Description:Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  53nMAssay Description:Concentration required for the inhibition of Cholesterol O-acyl transferase from HepG2 sonicateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  62nMAssay Description:Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from cholesterol fed rabbit liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50368461(CHEMBL1794871)
Affinity DataIC50:  64nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003829(2-(3,3-Diethoxy-propylsulfanyl)-4,5-diphenyl-1H-im...)
Affinity DataIC50:  69nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  69nMAssay Description:Concentration required for the inhibition of Cholesterol O-acyl transferase from human liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  79nMAssay Description:Concentration required for the inhibition of Cholesterol O-acyl transferase from cholesterol fed rabbit adrenalMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  80nMAssay Description:Compound was evaluated for inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in microsomes from rabbit adrenal.More data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003846(2-(4,5-Diphenyl-1H-imidazol-2-ylsulfanylmethyl)-6-...)
Affinity DataIC50:  82nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50051884(1-[5-(4,5-Diphenyl-1H-imidazole-2-sulfinyl)-pentyl...)
Affinity DataIC50:  86nMAssay Description:Compound was evaluated for inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in microsomes from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003813(2-(4,5-Diphenyl-1H-imidazol-2-ylsulfanylmethyl)-6-...)
Affinity DataIC50:  90nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  92nMAssay Description:Concentration required for the inhibition of Cholesterol O-acyl transferase from marmoset adrenalMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003825(2-Cyclohexylmethylsulfanyl-4,5-diphenyl-1H-imidazo...)
Affinity DataIC50:  100nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003808(6-(4,5-Diphenyl-1H-imidazol-2-ylsulfanylmethyl)-4,...)
Affinity DataIC50:  100nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50051884(1-[5-(4,5-Diphenyl-1H-imidazole-2-sulfinyl)-pentyl...)
Affinity DataIC50:  108nMAssay Description:Compound was evaluated for inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in microsomes from HEP G2 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  108nMAssay Description:Compound was evaluated for inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in microsomes from rabbit liver.More data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003830(6-[4,5-Bis-(3-chloro-phenyl)-1H-imidazol-2-ylsulfa...)
Affinity DataIC50:  110nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  119nMAssay Description:Concentration required for the inhibition of Cholesterol O-acyl transferase from cholesterol fed rabbit arteryMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50051884(1-[5-(4,5-Diphenyl-1H-imidazole-2-sulfinyl)-pentyl...)
Affinity DataIC50:  122nMAssay Description:Compound was evaluated for inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in microsomes from rabbit intestine.More data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003818(6-[4,5-Bis-(2-chloro-phenyl)-1H-imidazol-2-ylsulfa...)
Affinity DataIC50:  140nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003838(6-(4,5-Diphenyl-1H-imidazol-2-ylsulfanylmethyl)-4-...)
Affinity DataIC50:  140nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003839(6-(4,5-Diphenyl-1H-imidazol-2-ylsulfanylmethyl)-4-...)
Affinity DataIC50:  160nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50051884(1-[5-(4,5-Diphenyl-1H-imidazole-2-sulfinyl)-pentyl...)
Affinity DataIC50:  164nMAssay Description:Compound was evaluated for inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in microsomes from THP-1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003842(6-(4,5-Diphenyl-1H-imidazol-2-ylsulfanylmethyl)-4-...)
Affinity DataIC50:  170nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50368458(CHEMBL1794872)
Affinity DataIC50:  170nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003814(2-([1,3]Dioxan-2-ylmethylsulfanyl)-4,5-diphenyl-1H...)
Affinity DataIC50:  180nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280418(2-[4-(1-Methyl-1H-imidazol-2-ylsulfanyl)-butylsulf...)
Affinity DataIC50:  180nMAssay Description:Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from cholesterol fed rabbit liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003847(6-[4,5-Bis-(4-chloro-phenyl)-1H-imidazol-2-ylsulfa...)
Affinity DataIC50:  180nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50003834(6-(4,5-Diphenyl-1H-imidazol-2-ylsulfanylmethyl)-4-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50051884(1-[5-(4,5-Diphenyl-1H-imidazole-2-sulfinyl)-pentyl...)
Affinity DataIC50:  208nMAssay Description:Compound was evaluated for inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in microsomes from rabbit intestine.More data for this Ligand-Target Pair
In DepthDetails Article
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