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Found 6 Enz. Inhib. hit(s) with Target = 'Acyl-CoA:cholesterol acyltransferase' and Ligand = 'BDBM50051884'
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50051884(1-[5-(4,5-Diphenyl-1H-imidazole-2-sulfinyl)-pentyl...)
Affinity DataIC50:  75nMAssay Description:Inhibitory concentration of the compound was evaluated as concentration required to inhibit 50% activity of the rabbit liver Acyl coenzyme A:choleste...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50051884(1-[5-(4,5-Diphenyl-1H-imidazole-2-sulfinyl)-pentyl...)
Affinity DataIC50:  122nMAssay Description:Compound was evaluated for inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in microsomes from rabbit intestine.More data for this Ligand-Target Pair
In DepthDetails Article
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50051884(1-[5-(4,5-Diphenyl-1H-imidazole-2-sulfinyl)-pentyl...)
Affinity DataIC50:  150nMAssay Description:Inhibitory concentration of the compound was evaluated as concentration required to inhibit 50% activity of the rabbit artery Acyl coenzyme A:cholest...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50051884(1-[5-(4,5-Diphenyl-1H-imidazole-2-sulfinyl)-pentyl...)
Affinity DataIC50:  208nMAssay Description:Compound was evaluated for inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in microsomes from rabbit intestine.More data for this Ligand-Target Pair
In DepthDetails Article
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50051884(1-[5-(4,5-Diphenyl-1H-imidazole-2-sulfinyl)-pentyl...)
Affinity DataIC50:  245nMAssay Description:Compound was evaluated for inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in microsomes from rabbit artery.More data for this Ligand-Target Pair
In DepthDetails Article
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50051884(1-[5-(4,5-Diphenyl-1H-imidazole-2-sulfinyl)-pentyl...)
Affinity DataIC50:  370nMAssay Description:Compound was evaluated for inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in microsomes from rabbit adrenal.More data for this Ligand-Target Pair
In DepthDetails Article