Compile Data Set for Download or QSAR
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Found 21 with Last Name = 'carabateas' and Initial = 'pm'
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50036480(2,6-Dichloro-3-(2-morpholin-4-yl-ethoxy)-benzoic a...)
Affinity DataKi:  0.00800nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50036478(3-Carboxymethoxy-2,6-dichloro-benzoic acid 4-isopr...)
Affinity DataKi:  0.0110nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50036476(2,6-Dichloro-3-(4-methyl-piperazine-1-sulfonyl)-be...)
Affinity DataKi:  0.0110nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50036481(2,6-Dichloro-3-[(2-dimethylamino-ethyl)-methyl-sul...)
Affinity DataKi:  0.0130nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50036477(2,6-Dichloro-3-(2-morpholin-4-yl-ethoxy)-benzoic a...)
Affinity DataKi:  0.0130nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50036475(2,6-Dichloro-3-(2-pyrrolidin-1-yl-ethoxy)-benzoic ...)
Affinity DataKi:  0.0140nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50036482(2,6-Dichloro-3-(4-methyl-piperazine-1-sulfonyl)-be...)
Affinity DataKi:  0.200nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Sterling Winthrop

Curated by ChEMBL
LigandPNGBDBM50036479(1,1-Dioxo-2-(1-phenyl-1H-tetrazol-5-ylsulfanylmeth...)
Affinity DataKi:  15nMAssay Description:Potency of inhibition against human leukocyte elastase (HLE) expressed as an apparent binding constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sterling Winthrop Research

Curated by ChEMBL
LigandPNGBDBM50407402(CHEMBL2093896)
Affinity DataIC50:  2.10E+4nMAssay Description:Blockade of the delayed rectifier K+ current (IKr) of guinea pig myocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sterling Winthrop Research

Curated by ChEMBL
LigandPNGBDBM50407403(CHEMBL2092889)
Affinity DataIC50:  2.90E+4nMAssay Description:Blockade of the delayed rectifier K+ current (IKr) of guinea pig myocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Sterling Winthrop Research

Curated by ChEMBL
LigandPNGBDBM50407402(CHEMBL2093896)
Affinity DataIC50: >3.00E+4nMAssay Description:Blockade of Na+ current in frog oocytes expressing human cardiac sodium channel (HH1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Sterling Winthrop Research

Curated by ChEMBL
LigandPNGBDBM50407402(CHEMBL2093896)
Affinity DataIC50: >3.00E+4nMAssay Description:Blockade of Na+ current in frog oocytes expressing human cardiac sodium channel (HH1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Sterling Winthrop Research

Curated by ChEMBL
LigandPNGBDBM50407403(CHEMBL2092889)
Affinity DataIC50: >3.00E+4nMAssay Description:Blockade of Na+ current in frog oocytes expressing human cardiac sodium channel (HH1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sterling Winthrop Research

Curated by ChEMBL
LigandPNGBDBM50369030(CHEMBL1788206)
Affinity DataIC50:  3.80E+4nMAssay Description:Blockade of the delayed rectifier K+ current (IKr) of guinea pig myocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sterling Winthrop Research

Curated by ChEMBL
LigandPNGBDBM50407404(CHEMBL2092890)
Affinity DataIC50:  3.80E+4nMAssay Description:Blockade of the delayed rectifier K+ current (IKr) of guinea pig myocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sterling Winthrop Research

Curated by ChEMBL
LigandPNGBDBM50031720((Dofetilide) N-[4-(2-{[2-(4-Methanesulfonylamino-p...)
Affinity DataIC50:  4.40E+4nMAssay Description:Blockade of the delayed rectifier K+ current (IKr) of guinea pig myocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sterling Winthrop Research

Curated by ChEMBL
LigandPNGBDBM50369029(CHEMBL1788304)
Affinity DataIC50:  8.50E+4nMAssay Description:Blockade of the delayed rectifier K+ current (IKr) of guinea pig myocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Sterling Winthrop Research

Curated by ChEMBL
LigandPNGBDBM50407404(CHEMBL2092890)
Affinity DataIC50: >1.00E+5nMAssay Description:Blockade of Na+ current in frog oocytes expressing human cardiac sodium channel (HH1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Sterling Winthrop Research

Curated by ChEMBL
LigandPNGBDBM50369029(CHEMBL1788304)
Affinity DataIC50: >1.00E+5nMAssay Description:Blockade of Na+ current in frog oocytes expressing human cardiac sodium channel (HH1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Sterling Winthrop Research

Curated by ChEMBL
LigandPNGBDBM50369030(CHEMBL1788206)
Affinity DataIC50:  1.26E+5nMAssay Description:Blockade of Na+ current in frog oocytes expressing human cardiac sodium channel (HH1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Sterling Winthrop Research

Curated by ChEMBL
LigandPNGBDBM50031720((Dofetilide) N-[4-(2-{[2-(4-Methanesulfonylamino-p...)
Affinity DataIC50: >3.00E+5nMAssay Description:Blockade of Na+ current in frog oocytes expressing human cardiac sodium channel (HH1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed