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Found 94 with Last Name = 'castrillo' and Initial = 'a'
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163525(CHEMBL179972 | N-(4-Benzoyl-phenyl)-2-[4-(2-oxo-4H...)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163516(2-[4-(6-Fluoro-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-...)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163541(2-[4-(6-Chloro-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-...)
Affinity DataIC50:  8nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163539(CHEMBL557802 | N-(9-Hydroxy-9H-fluoren-3-yl)-2-[4-...)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163552(CHEMBL557540 | N-(9-Methyl-9H-carbazol-3-yl)-2-[4-...)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163513(CHEMBL541121 | N-(4-Benzoyl-phenyl)-2-[4-(6-chloro...)
Affinity DataIC50:  11.2nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163545(CHEMBL537412 | N-(4-Acetyl-phenyl)-2-[4-(2-oxo-4H-...)
Affinity DataIC50:  17.3nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163535(2-[4-(2-Oxo-4H-benzo[d][1,3]oxazin-1-yl)-piperidin...)
Affinity DataIC50:  20nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163526(CHEMBL537191 | N-(4-Acetyl-phenyl)-2-[4-(6-chloro-...)
Affinity DataIC50:  21nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Gnf

LigandPNGBDBM19992(2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methy...)
Affinity DataIC50:  23nMAssay Description:SPA assays were run in displacement mode using 30 nM [3H]-GW3965. Ligands were tested in 12-point dose-response curves starting at 20 uM. IC50 values...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163512(2-[4-(2-Oxo-4H-benzo[d][1,3]oxazin-1-yl)-piperidin...)
Affinity DataIC50:  23.3nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163538(2-[4-(6-Chloro-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-...)
Affinity DataIC50:  25nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163548(CHEMBL537187 | N-(4-Acetyl-phenyl)-2-[4-(6-methyl-...)
Affinity DataIC50:  26nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163529(CHEMBL535824 | N-(9-Hydroxy-9H-fluoren-3-yl)-2-[4-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163511(CHEMBL536276 | N-(4-Benzoyl-phenyl)-2-[4-(8-methyl...)
Affinity DataIC50:  39.6nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163521(2-[4-(8-Methyl-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-...)
Affinity DataIC50:  50nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163514(CHEMBL540365 | N-(9-Ethyl-9H-carbazol-3-yl)-2-[4-(...)
Affinity DataIC50:  50nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163531(CHEMBL557817 | N-(9-Ethyl-9H-carbazol-3-yl)-2-[4-(...)
Affinity DataIC50:  54.6nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163540(CHEMBL365777 | N-Dibenzofuran-2-yl-2-[4-(8-methoxy...)
Affinity DataIC50:  55.7nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163550(2-[4-(6-Chloro-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-...)
Affinity DataIC50:  60.7nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Gnf

LigandPNGBDBM20132((2R)-5-(4-chlorophenyl)-2-(2,3-dimethoxyphenyl)-3-...)
Affinity DataIC50:  66nMAssay Description:SPA assays were run in displacement mode using 30 nM [3H]-GW3965. Ligands were tested in 12-point dose-response curves starting at 20 uM. IC50 values...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163530(2-[4-(6-Chloro-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-...)
Affinity DataIC50:  69nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163533(2-[4-(6-Methyl-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-...)
Affinity DataIC50:  86.7nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163524(2-[4-(5-Chloro-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163519(2-[4-(6-Methyl-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-...)
Affinity DataIC50:  104nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163522(2-[4-(6-Chloro-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-...)
Affinity DataIC50:  112nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Gnf

LigandPNGBDBM19992(2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methy...)
Affinity DataIC50:  121nMAssay Description:SPA assays were run in displacement mode using 30 nM [3H]-GW3965. Ligands were tested in 12-point dose-response curves starting at 20 uM. IC50 values...More data for this Ligand-Target Pair
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163549(CHEMBL556999 | N-(4-Cyano-phenyl)-2-[4-(2-oxo-4H-b...)
Affinity DataIC50:  132nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163520(2-[4-(2-Oxo-4H-benzo[d][1,3]oxazin-1-yl)-piperidin...)
Affinity DataIC50:  138nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163547(2-[4-(6-Chloro-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-...)
Affinity DataIC50:  148nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163532(2-[4-(6-Chloro-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-...)
Affinity DataIC50:  199nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163528(CHEMBL558393 | N-(4-Chloro-phenyl)-2-[4-(2-oxo-4H-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Gnf

LigandPNGBDBM20131(5-(4-chlorophenyl)-2-(2,3-dimethoxyphenyl)-3-[(2,4...)
Affinity DataIC50:  300nMAssay Description:SPA assays were run in displacement mode using 30 nM [3H]-GW3965. Ligands were tested in 12-point dose-response curves starting at 20 uM. IC50 values...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163542(CHEMBL538569 | N-(9-Ethyl-9H-carbazol-3-yl)-2-[4-(...)
Affinity DataIC50:  765nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163551(2-[4-(8-Methyl-2-oxo-4H-benzo[d][1,3]oxazin-1-yl)-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163515(CHEMBL536496 | N-(4-Cyclohexyl-phenyl)-2-[4-(2-oxo...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163534(CHEMBL536729 | N-(2-Benzoyl-phenyl)-2-[4-(6-chloro...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163536(CHEMBL534483 | N-(4-Chloro-phenyl)-2-[4-(8-methyl-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163537(2-{2-[4-(2-Oxo-4H-benzo[d][1,3]oxazin-1-yl)-piperi...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163543(2-{2-[4-(8-Methyl-2-oxo-4H-benzo[d][1,3]oxazin-1-y...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163544(2-{2-[4-(6-Methyl-2-oxo-4H-benzo[d][1,3]oxazin-1-y...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163546(2-[4-(2-Oxo-4H-benzo[d][1,3]oxazin-1-yl)-piperidin...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163527(CHEMBL553250 | N-(2-Benzoyl-phenyl)-2-[4-(8-methyl...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163518(2-[4-(2-Oxo-4H-benzo[d][1,3]oxazin-1-yl)-piperidin...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163517(2-{2-[4-(6-Chloro-2-oxo-4H-benzo[d][1,3]oxazin-1-y...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide Y receptor type 5(Rat 6B)
Laboratorios Dr. Esteve

Curated by ChEMBL
LigandPNGBDBM50163523(CHEMBL534710 | N-(2-Benzoyl-phenyl)-2-[4-(2-oxo-4H...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of [125I]PYY binding to the rat NPY Y5 receptor in C6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Gnf

LigandPNGBDBM20132((2R)-5-(4-chlorophenyl)-2-(2,3-dimethoxyphenyl)-3-...)
Affinity DataIC50:  5.00E+3nMAssay Description:SPA assays were run in displacement mode using 30 nM [3H]-GW3965. Ligands were tested in 12-point dose-response curves starting at 20 uM. IC50 values...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Gnf

LigandPNGBDBM20131(5-(4-chlorophenyl)-2-(2,3-dimethoxyphenyl)-3-[(2,4...)
Affinity DataIC50:  9.80E+3nMAssay Description:SPA assays were run in displacement mode using 30 nM [3H]-GW3965. Ligands were tested in 12-point dose-response curves starting at 20 uM. IC50 values...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Gnf

LigandPNGBDBM19992(2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methy...)
Affinity DataEC50:  97nMpH: 7.2 T: 2°CAssay Description:FRET-based co-activator recruitment assay measures agonist activities in a 384-well plate format. Reaction mixture containing His-tagged hLXR, biotin...More data for this Ligand-Target Pair
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Gnf

LigandPNGBDBM20131(5-(4-chlorophenyl)-2-(2,3-dimethoxyphenyl)-3-[(2,4...)
Affinity DataEC50:  2.30E+3nMpH: 7.2 T: 2°CAssay Description:FRET-based co-activator recruitment assay measures agonist activities in a 384-well plate format. Reaction mixture containing His-tagged hLXR, biotin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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