Affinity DataKi: 61.1nMAssay Description:Inhibition of human recombinant AChE-mediated hydrolysis of acetylcholine by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.54nMAssay Description:Inhibition of human recombinant AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.65nMAssay Description:Inhibition of human recombinant AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.15nMAssay Description:Inhibition of human recombinant AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Bologna
Curated by ChEMBL
University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human ERG expressed in HEK cells by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Bologna
Curated by ChEMBL
University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 2.51nMAssay Description:Inhibition of human ERG expressed in HEK cells by patch clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.57nMAssay Description:Inhibition of human recombinant AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Bologna
Curated by ChEMBL
University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 15.8nMAssay Description:Inhibition of human ERG expressed in HEK cells by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Bologna
Curated by ChEMBL
University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human ERG expressed in HEK cells by patch clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant AChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 21.5nMAssay Description:Inhibition of human recombinant AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Bologna
Curated by ChEMBL
University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 39.8nMAssay Description:Inhibition of human ERG expressed in HEK cells by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Bologna
Curated by ChEMBL
University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of human ERG expressed in HEK cells by patch clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of human recombinant AChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 45.8nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of human recombinant AChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of human recombinant AChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Bologna
Curated by ChEMBL
University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 62nMAssay Description:Inhibition of human ERG expressed in HEK cells by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Bologna
Curated by ChEMBL
University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 63.1nMAssay Description:Inhibition of human ERG expressed in HEK cells by patch clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant AChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 137nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant AChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant AChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 189nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant AChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Bologna
Curated by ChEMBL
University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 192nMAssay Description:Inhibition of human ERG expressed in HEK cells by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Bologna
Curated by ChEMBL
University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of human ERG expressed in HEK cells by patch clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant AChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 211nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 296nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant AChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 424nMAssay Description:Inhibition of human recombinant AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Inhibition of human recombinant AChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Bologna
Curated by ChEMBL
University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Inhibition of human ERG expressed in HEK cells by patch clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Inhibition of human recombinant AChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Bologna
Curated by ChEMBL
University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 631nMAssay Description:Inhibition of human ERG expressed in HEK cells by patch clamp assayMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
University Of Bologna
Curated by ChEMBL
University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 740nMAssay Description:Inhibition of NMDA NR1/NR2B receptor (unknown origin) expressed in xenopus oocytes assessed as inhibition of NMDA and glycine-induced current respons...More data for this Ligand-Target Pair
Affinity DataIC50: 890nMAssay Description:Inhibition of human recombinant AChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 890nMAssay Description:Inhibition of human recombinant AChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of human recombinant AChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of human recombinant AChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of human recombinant AChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibition of human recombinant AChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.58E+3nMAssay Description:Inhibition of human serum BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human BuChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Bologna
Curated by ChEMBL
University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 2.79E+3nMAssay Description:Inhibition of human ERG expressed in HEK cells by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Bologna
Curated by ChEMBL
University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 2.79E+3nMAssay Description:Inhibition of human ERG expressed in HEK cells by patch clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human recombinant AChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.52E+3nMAssay Description:Inhibition of human BuChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.95E+3nMAssay Description:Inhibition of human recombinant AChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair