BindingDB PrimarySearch_ki

Found 1852 with Last Name = 'cen' and Initial = 's'

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50576898(CHEMBL4877646)

Ki: 0.0290nMAssay Description:Inhibition of wild type HIV1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincubated for 20 to 30 mi...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50576910(CHEMBL4862758)

Ki: 0.0400nMAssay Description:Inhibition of wild type HIV1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincubated for 20 to 30 mi...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50541871(CHEMBL4640442)

Ki: 0.0900nMAssay Description:Inhibition of wild type HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrat...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50576913(CHEMBL4868812)

Ki: 0.100nMAssay Description:Inhibition of wild type HIV1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincubated for 20 to 30 mi...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50576900(CHEMBL4852688)

Ki: 0.100nMAssay Description:Inhibition of wild type HIV1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincubated for 20 to 30 mi...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Indoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Pharmaron Beijing

Curated by ChEMBL

PNG

BDBM50604026(CHEMBL5192384)

Ki: 0.110nMAssay Description:Displacement of [3H] labeled-N-(4-Fluorophenyl)-3-(4-(4-(2-hydroxypropan-2-yl)-6-(trifluoromethyl)pyridin-3-yl)phenyl)oxetane-3-carboxamide from huma...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase PC cid PC sid

Indoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Pharmaron Beijing

Curated by ChEMBL

PNG

BDBM50604023(CHEMBL5192977)

Ki: 0.150nMAssay Description:Displacement of [3H] labeled-N-(4-Fluorophenyl)-3-(4-(4-(2-hydroxypropan-2-yl)-6-(trifluoromethyl)pyridin-3-yl)phenyl)oxetane-3-carboxamide from huma...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Details PubMed PDB

3D Structure (crystal)

Fatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL

PNG

BDBM50395423(CHEMBL2165084)

Ki: 0.160nMAssay Description:Inhibition of mouse FAAH isolated from brain homogenate using [3H-ethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition mea...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Fatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL

PNG

BDBM50395424(CHEMBL2165083)

Ki: 0.180nMAssay Description:Inhibition of mouse FAAH isolated from brain homogenate using [3H-ethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition mea...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM8125((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)

Ki: 0.180nMAssay Description:Inhibition of wild type HIV1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincubated for 20 to 30 mi...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Purchase ChEBI
CHEMBL DrugBank MCE
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Details Article PubMed DrugBank
PDB

3D Structure (crystal)

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50576912(CHEMBL4861507)

Ki: 0.190nMAssay Description:Inhibition of wild type HIV1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincubated for 20 to 30 mi...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50541883(CHEMBL4643409)

Ki: 0.210nMAssay Description:Inhibition of wild type HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrat...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50576899(CHEMBL4852584)

Ki: 0.270nMAssay Description:Inhibition of wild type HIV1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincubated for 20 to 30 mi...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50576914(CHEMBL4866330)

Ki: 0.280nMAssay Description:Inhibition of wild type HIV1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincubated for 20 to 30 mi...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50576916(CHEMBL4875282)

Ki: 0.300nMAssay Description:Inhibition of wild type HIV1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincubated for 20 to 30 mi...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50576911(CHEMBL4863180)

Ki: 0.300nMAssay Description:Inhibition of wild type HIV1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincubated for 20 to 30 mi...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50576904(CHEMBL4860352)

Ki: 0.330nMAssay Description:Inhibition of wild type HIV1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincubated for 20 to 30 mi...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM8125((3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S...)

Ki: 0.340nMAssay Description:Inhibition of wild type HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrat...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Purchase ChEBI
CHEMBL DrugBank MCE
MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed DrugBank
PDB

3D Structure (crystal)

Fatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL

PNG

BDBM50395421(CHEMBL2165094)

Ki: 0.490nMAssay Description:Inhibition of mouse FAAH isolated from brain homogenate using [3H-ethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition mea...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Fatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL

PNG

BDBM50395420(CHEMBL2165070)

Ki: 0.5nMAssay Description:Inhibition of mouse FAAH isolated from brain homogenate using [3H-ethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition mea...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50576907(CHEMBL4877811)

Ki: 0.550nMAssay Description:Inhibition of wild type HIV1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincubated for 20 to 30 mi...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Histamine H3 receptor(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL

PNG

BDBM50089369(CHEMBL3577959)

Ki: 0.700nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50541873(CHEMBL4645562)

Ki: 0.860nMAssay Description:Inhibition of wild type HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrat...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Histamine H3 receptor(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL

PNG

BDBM50089374(CHEMBL3577954)

Ki: 1nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50576917(CHEMBL4868304)

Ki: 1nMAssay Description:Inhibition of wild type HIV1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincubated for 20 to 30 mi...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Histamine H3 receptor(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL

PNG

BDBM50089375(CHEMBL3577953)

Ki: 1nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Fatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL

PNG

BDBM26739(3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate ...)

Ki: 1.20nMAssay Description:Inhibition of mouse FAAH isolated from brain homogenate using [3H-ethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition mea...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Purchase CHEMBL MCE
PC cid PC sid Patents Similars

Details Article PubMed

Histamine H3 receptor(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL

PNG

BDBM50346208((1-isopropylpiperidin-4-yl)(4-(piperidin-1-ylmethy...)

Ki: 1.30nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Histamine H3 receptor(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL

PNG

BDBM50089372(CHEMBL3577956)

Ki: 1.30nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Histamine H3 receptor(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL

PNG

BDBM50089370(CHEMBL3577958)

Ki: 1.5nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50576915(CHEMBL4858570)

Ki: 1.70nMAssay Description:Inhibition of wild type HIV1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincubated for 20 to 30 mi...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50576905(CHEMBL4850187)

Ki: 2nMAssay Description:Inhibition of wild type HIV1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincubated for 20 to 30 mi...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Histamine H3 receptor(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL

PNG

BDBM50089368(CHEMBL3577960)

Ki: 2nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50541872(CHEMBL4635435)

Ki: 2.20nMAssay Description:Inhibition of wild type HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrat...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Histamine H3 receptor(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL

PNG

BDBM50089373(CHEMBL3577955)

Ki: 2.5nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50576918(CHEMBL4877064)

Ki: 2.60nMAssay Description:Inhibition of wild type HIV1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincubated for 20 to 30 mi...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Amine oxidase [flavin-containing] A(Homo sapiens (Human))
Facult£S Universitaires Notre-Dame De La Paix

Curated by ChEMBL

PNG

BDBM50333418(7-(4,4,4-Trifluorobutoxy)-1-methyl-beta-carboline ...)

Ki: 3.60nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus-infected Bacillus thuringiensis israelensis cells after 1 hr by two-step bioluminescen...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Amine oxidase [flavin-containing] A(Homo sapiens (Human))
Facult£S Universitaires Notre-Dame De La Paix

Curated by ChEMBL

PNG

BDBM50333415(7-(Isobutyloxy)-1-methyl-beta-carboline | CHEMBL16...)

Ki: 3.90nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus-infected Bacillus thuringiensis israelensis cells after 1 hr by two-step bioluminescen...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Amine oxidase [flavin-containing] A(Homo sapiens (Human))
Facult£S Universitaires Notre-Dame De La Paix

Curated by ChEMBL

PNG

BDBM50333419(7-(Cyclohexylmethoxy)-1-methyl-beta-carboline | CH...)

Ki: 4.30nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus-infected Bacillus thuringiensis israelensis cells after 1 hr by two-step bioluminescen...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50576906(CHEMBL4857293)

Ki: 4.60nMAssay Description:Inhibition of wild type HIV1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincubated for 20 to 30 mi...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Fatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL

PNG

BDBM50395427(CHEMBL2165073)

Ki: 4.80nMAssay Description:Inhibition of mouse FAAH isolated from brain homogenate using [3H-ethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition mea...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Amine oxidase [flavin-containing] A(Homo sapiens (Human))
Facult£S Universitaires Notre-Dame De La Paix

Curated by ChEMBL

PNG

BDBM50333421(7-(Phenethoxy)-1-methyl-beta-carboline | CHEMBL164...)

Ki: 5nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus-infected Bacillus thuringiensis israelensis cells after 1 hr by two-step bioluminescen...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Histamine H3 receptor(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL

PNG

BDBM50089378(CHEMBL3577951)

Ki: 5nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid Similars

Details Article PubMed

Amine oxidase [flavin-containing] A(Homo sapiens (Human))
Facult£S Universitaires Notre-Dame De La Paix

Curated by ChEMBL

PNG

BDBM50333414(7-(Allyloxy)-1-methyl-beta-carboline | CHEMBL16455...)

Ki: 5nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus-infected Bacillus thuringiensis israelensis cells after 1 hr by two-step bioluminescen...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Histamine H3 receptor(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL

PNG

BDBM50089371(CHEMBL3577957)

Ki: 5.40nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50576908(CHEMBL4860374)

Ki: 5.5nMAssay Description:Inhibition of wild type HIV1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincubated for 20 to 30 mi...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50541877(CHEMBL4647025)

Ki: 5.70nMAssay Description:Inhibition of wild type HIV1 protease expressed in Escherichia coli using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrat...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Chinese Academy Of Medical Science And Peking Union Medical College

Curated by ChEMBL

PNG

BDBM50576909(CHEMBL4846696)

Ki: 5.90nMAssay Description:Inhibition of wild type HIV1 protease using Arg-Glu (EDANS)-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln-Lys(DABCYL)-Arg as substrate preincubated for 20 to 30 mi...More data for this Ligand-Target Pair

PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

Details Article PubMed

Histamine H3 receptor(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL

PNG

BDBM50089377(CHEMBL3577952)

Ki: 6nMAssay Description:Displacement of N-[3H]methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells after 45 minsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Fatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL

PNG

BDBM50395442(CHEMBL2165080)

Ki: 7nMAssay Description:Inhibition of mouse FAAH isolated from brain homogenate using [3H-ethanolamine]AEA as substrate incubated for 20 mins prior to substrate addition mea...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Displayed 1 to 50 (of 1852 total ) | Next | Last >>

Filter my 1852 hits

Targets 72▿
- C-C chemokine receptor type 1 209
- Gag-Pol polyprotein [489-587] 207
- Indoleamine 2,3-dioxygenase 1 182
- Gonadotropin-releasing hormone receptor 180
- Glucagon receptor 178
- Integrin alpha-4/beta-1 169
- Reverse transcriptase/RNaseH 74
- Potassium voltage-gated channel subfamily H member 2 63
- Protease 59
- Integrin alpha-4/beta-7 54
- Fatty-acid amide hydrolase 1 49
- Replicase polyprotein 1ab 34
- Tyrosine-protein kinase SYK 33
- Prolyl hydroxylase EGLN2 28
- Egl nine homolog 1 28
- Gastric inhibitory polypeptide receptor 28
- Prolyl hydroxylase EGLN3 26
- Cytochrome P450 3A4 18
- UDP-galactopyranose mutase 17
- Amine oxidase [flavin-containing] A 16
- Integrin alpha-4 15
- Nuclear receptor subfamily 1 group I member 2 14
- Carbonic anhydrase 3 14
- Histamine H3 receptor 13
- Cytochrome P450 2C9 12
- Prostaglandin E synthase 11
- Histone deacetylase 10
- Glucagon-like peptide 1 receptor 10
- Carbonic anhydrase 1 8
- Carbonic anhydrase 6 8
- Carbonic anhydrase 2 8
- Carbonic anhydrase 4 8
- Amine oxidase [flavin-containing] B 6
- Signal transducer and activator of transcription 1-alpha/beta 4
- Androgen receptor 4
- Cytochrome P450 2D6 4
- Vasoactive intestinal polypeptide receptor 2 4
- Fucose-binding lectin PA-IIL 3
- Leucine-rich repeat serine/threonine-protein kinase 2 3
- Nuclear factor of activated T-cells, cytoplasmic 1 3
- Stimulator of interferon genes protein 2
- 3-phosphoinositide-dependent protein kinase 1 2
- Cytochrome P450 1A2 2
- Cytochrome P450 2C19 2
- Protein kinase C alpha type 2
- Protein kinase C theta type 2
- Glucagon receptor [1-477] 1
- Chemokine (C-C motif) receptor 1 1
- Proto-oncogene tyrosine-protein kinase ROS 1
- Chemokine receptor 1
- DNA topoisomerase 2-beta 1
- Tyrosine-protein kinase Blk 1
- Sodium channel protein type 5 subunit alpha 1
- Dual specificity protein phosphatase 2 1
- DNA topoisomerase 2-alpha 1
- Serine/threonine-protein kinase TBK1 1
- Glucocorticoid receptor 1
- Cytochrome P450 2E1 1
- Voltage-dependent L-type calcium channel subunit alpha-1C 1
- 1,3-beta-glucan synthase component GSC2 1
- Testis-specific serine/threonine-protein kinase 3 1
- Cytochrome P450 2C8 1
- Vasoactive intestinal polypeptide receptor 1 1
- Uncharacterized protein [173-650] 1
- Serine/threonine-protein kinase Chk2 1
- Cysteinyl leukotriene receptor 2 1
- Tyrosine-protein kinase ZAP-70 1
- C-C chemokine receptor type 3 1
- C-C chemokine receptor type 2 1
- C-C chemokine receptor type 5 1
- Macrophage inflammatory protein-1 alpha receptor 1
- Cytochrome P450 2B6 1
- ...
Publications 48▿
- J Med Chem 55: 6137-48 (2012) 106
- Bioorg Med Chem Lett 23: 3833-40 (2013) 98
- ACS Med Chem Lett 9: 1193-1198 (2018) 88
- Bioorg Med Chem Lett 12: 827-32 (2002) 86
- Eur J Med Chem 220: (2021) 86
- J Med Chem 55: 9643-53 (2012) 85
- Bioorg Med Chem Lett 11: 2709-13 (2001) 79
- Bioorg Med Chem Lett 21: 7131-6 (2011) 78
- Eur J Med Chem 186: (2020) 65
- Bioorg Med Chem Lett 49: (2021) 59
- ACS Med Chem Lett 12: 389-396 (2021) 59
- Bioorg Med Chem Lett 11: 2597-602 (2001) 58
- J Med Chem 58: 1929-39 (2015) 58
- Bioorg Med Chem Lett 21: 7124-30 (2011) 55
- J Med Chem 55: 6898-915 (2012) 53
- Bioorg Med Chem Lett 47: (2021) 51
- Bioorg Med Chem Lett 12: 637-40 (2002) 51
- J Med Chem 57: 7550-64 (2014) 50
- Bioorg Med Chem Lett 12: 159-63 (2001) 47
- J Enzyme Inhib Med Chem 28: 412-7 (2013) 46
- J Med Chem 65: 6001-6016 (2022) 41
- Bioorg Med Chem Lett 12: 3329-32 (2002) 36
- Bioorg Med Chem Lett 29: 1541-1545 (2019) 34
- Eur J Med Chem 223: (2021) 34
- Bioorg Med Chem Lett 12: 611-4 (2002) 31
- Bioorg Med Chem 28: (2020) 29
- Bioorg Med Chem 64: (2022) 27
- Eur J Med Chem 233: (2022) 27
- Eur J Med Chem 185: (2020) 25
- ACS Med Chem Lett 6: 450-4 (2015) 25
- ACS Med Chem Lett 11: 1196-1204 (2020) 25
- Eur J Med Chem 220: (2021) 22
- J Nat Prod 78: 2867-79 (2015) 21
- Bioorg Med Chem 19: 134-44 (2011) 18
- Bioorg Med Chem 69: (2022) 17
- J Med Chem 52: 3449-52 (2009) 17
- Bioorg Med Chem Lett 17: 597-601 (2007) 15
- ACS Med Chem Lett 12: 1435-1440 (2021) 12
- J Med Chem 44: 917-22 (2001) 8
- Bioorg Med Chem 20: 3596-602 (2012) 6
- Eur J Med Chem 46: 6104-11 (2011) 4
- J Nat Prod 77: 543-9 (2014) 4
- Eur J Med Chem 238: (2022) 3
- Eur J Med Chem 182: (2019) 3
- ACS Med Chem Lett 7: 1024-1027 (2016) 3
- J Med Chem 64: 14728-14744 (2021) 3
- Eur J Med Chem 166: 232-242 (2019) 2
- J Nat Prod 82: 2768-2779 (2019) 2
Institutions 18▿
- Merck Research Laboratories 667
- Chinese Academy Of Medical Science And Peking Union Medical College 347
- Merck 327
- Bristol-Myers Squibb 233
- Universit£ 63
- Ege University 46
- Pharmaron Beijing 41
- Chinese Academy Of Medical Sciences And Peking Union Medical College 27
- Janssen Pharmaceutical Companies Of Johnson & Johnson 25
- Mashhad University Of Medical Sciences 21
- Facult£S Universitaires Notre-Dame De La Paix 18
- Guizhou University Of Traditional Chinese Medicine 17
- Zhejiang Normal University 5
- Facult£S Universitaires Notre-Dame De Paix 4
- Chinese Academy Of Medical Science 3
- University Of Namur (Unamur) 3
- Universitat Aut£Noma De Barcelona 3
- European Biomedical Research Institute Of Salerno (Ebris) 2
Affinity: 0.010 to 6.0E+7 nM▿
- Ki 144
- IC50 1666
- Kd 25
- EC50 17
- Affinity ≤ nM
Xtal structures: 18
Docked structures: 4
Catalog Cmpds: 46