Affinity DataKi: 1.23nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in rat cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 2.75nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in rat cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 18.6nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 243nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 247nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in rat cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 311nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in rat cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 353nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 692nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 905nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.45E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.74E+3nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in rat cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 1.88E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.11E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.16E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.62E+3nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in rat cerebellumMore data for this Ligand-Target Pair
Affinity DataKi: 3.31E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.80E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.03E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.97E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6.30E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6.31E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6.46E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6.66E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 7.03E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: >8.00E+3nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:The compound was evaluated for prostaglandin E2 inhibition using recombinant Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:The compound was evaluated for its inhibitory activity against Prostaglandin G/H synthase 2 using osteosarcomes cellsMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Laboratoires Innothera
Curated by ChEMBL
Laboratoires Innothera
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:The compound was evaluated for its inhibitory activity against 5-lipoxygenase using granulocytes-type cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of COX1 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:The compound was evaluated for its inhibitory activity against Prostaglandin G/H synthase 2 using osteosarcomes cellsMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Laboratoires Innothera
Curated by ChEMBL
Laboratoires Innothera
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:The compound was evaluated for prostaglandin E2 inhibition using recombinant Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:The compound was evaluated for prostaglandin E2 inhibition using recombinant Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
Affinity DataIC50: 103nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Laboratoires Innothera
Curated by ChEMBL
Laboratoires Innothera
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of 5-lipoxygenase activity of compound evaluated as determined by the inhibition of calcium ionophore-induced leukotriene B4 production in...More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Laboratoires Innothera
Curated by ChEMBL
Laboratoires Innothera
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:The 5-lipoxygenase activity of the compound was determined by the inhibition of calcium ionophore-induced leukotriene B4 production in human blood.More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Laboratoires Innothera
Curated by ChEMBL
Laboratoires Innothera
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 331nMAssay Description:Inhibitory activity against human thrombinMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:The inhibitory activity against cyclooxygenase Prostaglandin G/H synthase 2 (COX-2) measured as PGE-2 production after blood coagulation using human ...More data for this Ligand-Target Pair
Affinity DataIC50: 410nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of COX2 expressed in CHO cells assessed as inhibition of arachidonic acid-stimulated PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Laboratoires Innothera
Curated by ChEMBL
Laboratoires Innothera
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of 5LOX in human whole blood assessed as inhibition of calcium ionophore A 23187-stimulated 5HETE production by HPLC analysisMore data for this Ligand-Target Pair