Compile Data Set for Download or QSAR
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Found 25 with Last Name = 'chen' and Initial = 'xj'
TargetMu-type opioid receptor(MOUSE)
Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50033531(CHEMBL333410 | N-[1-(2-Hydroxy-2-phenyl-ethyl)-3-m...)
Affinity DataKi:  0.00500nMAssay Description:Inhibition against Opioid receptor mu 1 using [3H]- DAMGO radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50033533(CHEMBL121403 | N-[(3R,4R)-1-((S)-2-Hydroxy-2-pheny...)
Affinity DataKi:  0.0600nMAssay Description:Inhibition against Opioid receptor mu 1 using [3H]- DAMGO radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50033534(CHEMBL338510 | N-[(3S,4S)-1-((S)-2-Hydroxy-2-pheny...)
Affinity DataKi:  0.0800nMAssay Description:Inhibition against Opioid receptor mu 1 using [3H]- DAMGO radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50033536(CHEMBL121494 | N-[(3R,4R)-1-((R)-2-Hydroxy-2-pheny...)
Affinity DataKi:  0.130nMAssay Description:Inhibition against Opioid receptor mu 1 using [3H]- DAMGO radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50033530(CHEMBL121211 | N-[(3S,4S)-1-((R)-2-Hydroxy-2-pheny...)
Affinity DataKi:  0.150nMAssay Description:Inhibition against Opioid receptor mu 1 using [3H]- DAMGO radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50033530(CHEMBL121211 | N-[(3S,4S)-1-((R)-2-Hydroxy-2-pheny...)
Affinity DataKi:  0.150nMAssay Description:Inhibition against Opioid receptor mu 1 using [3H]- DAMGO radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50033537(CHEMBL121060 | N-[(3S,4R)-1-((S)-2-Hydroxy-2-pheny...)
Affinity DataKi:  2.89nMAssay Description:Inhibition against Opioid receptor mu 1 using [3H]- DAMGO radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50033532(CHEMBL435380 | N-[(3S,4R)-1-((R)-2-Hydroxy-2-pheny...)
Affinity DataKi:  5.85nMAssay Description:Inhibition against Opioid receptor mu 1 using [3H]- DAMGO radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50033531(CHEMBL333410 | N-[1-(2-Hydroxy-2-phenyl-ethyl)-3-m...)
Affinity DataKi:  114nMAssay Description:Inhibition against delta-opioid receptor using [3H]-DPDPE radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50033536(CHEMBL121494 | N-[(3R,4R)-1-((R)-2-Hydroxy-2-pheny...)
Affinity DataKi:  150nMAssay Description:Inhibition against Opioid receptor delta 1 using [3H]-DPDPE radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50033533(CHEMBL121403 | N-[(3R,4R)-1-((S)-2-Hydroxy-2-pheny...)
Affinity DataKi:  200nMAssay Description:Inhibition against delta-opioid receptor using [3H]-DPDPE radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50033530(CHEMBL121211 | N-[(3S,4S)-1-((R)-2-Hydroxy-2-pheny...)
Affinity DataKi:  230nMAssay Description:Inhibition against delta-opioid receptor using [3H]-DPDPE radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50033530(CHEMBL121211 | N-[(3S,4S)-1-((R)-2-Hydroxy-2-pheny...)
Affinity DataKi:  230nMAssay Description:Inhibition against delta-opioid receptor using [3H]-DPDPE radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50033534(CHEMBL338510 | N-[(3S,4S)-1-((S)-2-Hydroxy-2-pheny...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition against delta-opioid receptor using [3H]-DPDPE radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50033537(CHEMBL121060 | N-[(3S,4R)-1-((S)-2-Hydroxy-2-pheny...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition against delta-opioid receptor using [3H]-DPDPE radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50033532(CHEMBL435380 | N-[(3S,4R)-1-((R)-2-Hydroxy-2-pheny...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition against delta-opioid receptor using [3H]-DPDPE radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-crystallin B chain(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50459239(CHEMBL4204376)
Affinity DataEC50:  18nMAssay Description:Inhibition of alpha-crystallin B R120G mutant (unknown origin)-induced intracellular protein aggregation expressed in human HeLa cells or HLE-B3 cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-crystallin B chain(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50459236(CHEMBL4203007)
Affinity DataEC50:  3.12E+3nMAssay Description:Induction of redissolving of aggregated alpha-crystallin B R120G mutant (unknown origin) incubated for 24 hrs by ThT-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-crystallin A chain(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50459236(CHEMBL4203007)
Affinity DataEC50:  36nMAssay Description:Induction of redissolving of aggregated alpha-crystallin A Y118D mutant (unknown origin) incubated for 24 hrs by ThT-fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-crystallin B chain(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50459238(CHEBI:16521 | LANOSTEROL | Lanostereol)
Affinity DataEC50:  1.42E+3nMAssay Description:Inhibition of alpha-crystallin B R120G mutant (unknown origin)-induced intracellular protein aggregation expressed in human HeLa cells or HLE-B3 cell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-crystallin B chain(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM20182((1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-6-hydroxy-6-me...)
Affinity DataEC50:  320nMAssay Description:Inhibition of alpha-crystallin B R120G mutant (unknown origin)-induced intracellular protein aggregation expressed in human HeLa cells or HLE-B3 cell...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-crystallin B chain(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50459237(CHEMBL4209249)
Affinity DataEC50:  26nMAssay Description:Inhibition of alpha-crystallin B R120G mutant (unknown origin)-induced intracellular protein aggregation expressed in human HeLa cells or HLE-B3 cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-crystallin B chain(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50459235(CHEMBL4218328)
Affinity DataEC50:  64nMAssay Description:Inhibition of alpha-crystallin B R120G mutant (unknown origin)-induced intracellular protein aggregation expressed in human HeLa cells or HLE-B3 cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-crystallin B chain(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50459240(CHEMBL4205794)
Affinity DataEC50:  106nMAssay Description:Inhibition of alpha-crystallin B R120G mutant (unknown origin)-induced intracellular protein aggregation expressed in human HeLa cells or HLE-B3 cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-crystallin B chain(Homo sapiens)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50459236(CHEMBL4203007)
Affinity DataEC50:  57nMAssay Description:Inhibition of alpha-crystallin B R120G mutant (unknown origin)-induced intracellular protein aggregation expressed in human HeLa cells or HLE-B3 cell...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed