Affinity DataKi: 0.940nMAssay Description:Displacement of [3H]-SCH-23390 from human dopamine D1 receptor expressed in HEK293 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D2long receptor expressed in HEK293 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 6.90nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 47nMAssay Description:Displacement of [3H]-SCH-23390 from human dopamine D1 receptor expressed in HEK293 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D2long receptor expressed in HEK293 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 210nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D2long receptor expressed in HEK293 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 490nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D2long receptor expressed in HEK293 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 550nMAssay Description:Displacement of [3H]-SCH-23390 from human dopamine D1 receptor expressed in HEK293 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 921nMAssay Description:Displacement of [3H]-SCH-23390 from human dopamine D1 receptor expressed in HEK293 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.43E+3nMAssay Description:Displacement of [3H]-N-methylspiperone from human dopamine D2long receptor expressed in HEK293 cells after 30 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.90E+5nMAssay Description:Inhibitory constant was measured on cytidine/deoxycytidine deaminaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.60E+6nMAssay Description:Inhibitory constant was measured on cytidine/deoxycytidine deaminaseMore data for this Ligand-Target Pair
Affinity DataKi: 7.69E+6nMAssay Description:Inhibitory constant was measured on cytidine/deoxycytidine deaminaseMore data for this Ligand-Target Pair
Affinity DataKi: 2.51E+7nMAssay Description:Inhibitory constant was measured on cytidine/deoxycytidine deaminaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.251nMAssay Description:Binding affinity to full-length BRD4 short isoform (unknown origin) by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.398nMAssay Description:Inhibition of human BRD4 bromodomain 1 by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.398nMAssay Description:Inhibition of human BRD4 bromodomain 1/2 by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.631nMAssay Description:Inhibition of human BRD3 bromodomain 1 by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
TargetBromodomain and PHD finger-containing protein 3(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of human BRPF3 by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: <1.30nMAssay Description:Inhibition of human BRD7 by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]-8-Hydroxy-2-(di-n-propylamino)tetralin binding to 5-hydroxytryptamine 1A receptor ...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human BRD3 bromodomain 2 by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor at 1 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Concentration of the compound necessary to achieve half maximal inhibition of [3H]-clonidine binding to Alpha-2 adrenergic receptor at 1 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Compound was evaluated in vitro for the inhibition of Thromboxane synthase using [14C]-arachidonic acid as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Concentration of the compound necessary to achieve half maximal inhibition of [3H]-8-Hydroxy-2-(di-n-propylamino)tetralin binding to 5-hydroxytryptam...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human BRD4 bromodomain 2 by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human BRD2 bromodomain 2 by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
Affinity DataIC50: <4nMAssay Description:Inhibition of human BRPF1 by BROMOscan assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]-8-Hydroxy-2-(di-n-propylamino)tetralin binding to 5-hydroxytryptamine 1A receptor ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Displacement of [3H]naloxone from Sprague-Dawley rat cerebellum opioid receptor assessed as relative receptor affinity by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Displacement of [3H]naloxone from Sprague-Dawley rat cerebellum opioid receptor assessed as relative receptor affinity by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:In vitro inhibition of thromboxane synthase using [14C]-arachidonic acidMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]-8-Hydroxy-2-(di-n-propylamino)tetralin binding to 5-hydroxytryptamine 1A receptor ...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of NEP 24.11 from rat kidneyMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H](+)-23amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene binding to dopamine recepto...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Displacement of [3H]naloxone from Sprague-Dawley rat cerebellum opioid receptor assessed as relative receptor affinity by scintillation countingMore data for this Ligand-Target Pair