TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 490nMAssay Description:Binding affinity to dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 950nMAssay Description:Binding affinity to norepinephrine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 2.90E+3nMAssay Description:Binding affinity to serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 6.50E+3nMAssay Description:Binding affinity to dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 7.70E+3nMAssay Description:Binding affinity to norepinephrine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 2.90E+4nMAssay Description:Binding affinity to serotonin transporterMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Rattus norvegicus)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.00700nMAssay Description:Inhibition of eotaxin-induced chemotaxis of rat eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.00700nMAssay Description:Inhibition of eotaxin-induced chemotaxis of human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Rattus norvegicus)
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of eotaxin-induced chemotaxis of rat eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.0100nMAssay Description:Antagonist activity at CCR3 assessed as eotaxin-induced chemotaxis in human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of eotaxin-induced chemotaxis of human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.0150nMAssay Description:Inhibition of eotaxin-induced chemotaxis of human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.0160nMAssay Description:Inhibition of eotaxin-induced chemotaxis of human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.0300nMAssay Description:Antagonist activity at CCR3 assessed as eotaxin-induced chemotaxis in human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.0300nMAssay Description:Inhibition of eotaxin-induced chemotaxis of human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.0340nMAssay Description:Inhibition of eotaxin-induced chemotaxis of human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.0340nMAssay Description:Antagonist activity at CCR3 assessed as eotaxin-induced chemotaxis in human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.0390nMAssay Description:Inhibition of eotaxin-induced chemotaxis of Cynomolgus monkey eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.0420nMAssay Description:Inhibition of eotaxin-induced chemotaxis of human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.0450nMAssay Description:Inhibition of eotaxin-induced chemotaxis of human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of eotaxin-induced chemotaxis of human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.0680nMAssay Description:Antagonist activity at CCR3 assessed as eotaxin-induced chemotaxis in human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.0750nMAssay Description:Antagonist activity at CCR3 assessed as eotaxin-induced chemotaxis in human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Inhibition of eotaxin-induced chemotaxis of human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Antagonist activity at CCR3 assessed as eotaxin-induced chemotaxis in human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of eotaxin-induced chemotaxis of human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.25nMAssay Description:Inhibition of eotaxin-induced chemotaxis of human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of [125I]eotaxin binding to human C-C chemokine receptor type 3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.364nMAssay Description:Inhibition of eotaxin-induced chemotaxis of human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of [125I]eotaxin binding to human C-C chemokine receptor type 3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of [125I]-eotaxin binding to human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of [125I]-eotaxin binding to human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Displacement of [125I]eotaxin from human CCR3 expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of [125I]eotaxin binding to human C-C chemokine receptor type 3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of [125I]eotaxin binding to human C-C chemokine receptor type 3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Displacement of [125I]eotaxin from human CCR3 expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Displacement of [125I]eotaxin from human CCR3 expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of [125I]eotaxin binding to human C-C chemokine receptor type 3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.800nMAssay Description:Inhibition of [125I]-eotaxin binding to human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Displacement of [125I]eotaxin from human CCR3 expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Displacement of [125I]eotaxin from human CCR3 expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Displacement of [125I]eotaxin from human CCR3 expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Displacement of [125I]eotaxin from human CCR3 expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Antagonist activity at CCR3 assessed as eotaxin-induced chemotaxis in human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of eotaxin-induced chemotaxis of human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of eotaxin-induced chemotaxis of human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of [125I]eotaxin binding to human C-C chemokine receptor type 3 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of eotaxin-induced chemotaxis of human eosinophilsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]eotaxin from human CCR3 expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of eotaxin-induced chemotaxis of human eosinophilsMore data for this Ligand-Target Pair