Compile Data Set for Download or QSAR
maximum 50k data
Found 18 with Last Name = 'dehertogh' and Initial = 'p'
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50288737(CHEMBL4168125)
Affinity DataIC50:  90nMAssay Description:Antagonist activity at 5-HT2B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50288739(CHEMBL4173963)
Affinity DataIC50:  230nMAssay Description:Antagonist activity at 5-HT2B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50288738(CHEMBL4159471)
Affinity DataIC50:  4.00E+3nMAssay Description:Antagonist activity at 5-HT2B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50288738(CHEMBL4159471)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50288738(CHEMBL4159471)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50288738(CHEMBL4159471)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50288738(CHEMBL4159471)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50288738(CHEMBL4159471)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50288738(CHEMBL4159471)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Janssen Pharmaceutical Companies Of Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM50288738(CHEMBL4159471)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Tibotec

Curated by ChEMBL
LigandPNGBDBM50336502(10-acetyl-11-(2,4-dichlorophenyl)-3,3-dimethyl-2,3...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase subunit gamma-1(Homo sapiens (Human))
Tibotec

Curated by ChEMBL
LigandPNGBDBM50336503(10-acetyl-11-(3-(benzyloxy)-4-methoxyphenyl)-3,3-d...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human DNA polymerase gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase subunit gamma-1(Homo sapiens (Human))
Tibotec

Curated by ChEMBL
LigandPNGBDBM50336502(10-acetyl-11-(2,4-dichlorophenyl)-3,3-dimethyl-2,3...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human DNA polymerase gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
Tibotec

Curated by ChEMBL
LigandPNGBDBM50336503(10-acetyl-11-(3-(benzyloxy)-4-methoxyphenyl)-3,3-d...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase beta(Homo sapiens (Human))
Tibotec

Curated by ChEMBL
LigandPNGBDBM50336502(10-acetyl-11-(2,4-dichlorophenyl)-3,3-dimethyl-2,3...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human DNA polymerase betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Tibotec

Curated by ChEMBL
LigandPNGBDBM50336503(10-acetyl-11-(3-(benzyloxy)-4-methoxyphenyl)-3,3-d...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human DNA polymerase alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Homo sapiens (Human))
Tibotec

Curated by ChEMBL
LigandPNGBDBM50336501(10-acetyl-11-(4-(benzyloxy)-2-chlorophenyl)-6-hydr...)
Affinity DataIC50: >3.00E+7nMAssay Description:Inhibition of peripheral benzodiazepine BZD receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranslocator protein(Homo sapiens (Human))
Tibotec

Curated by ChEMBL
LigandPNGBDBM50336501(10-acetyl-11-(4-(benzyloxy)-2-chlorophenyl)-6-hydr...)
Affinity DataIC50: >3.00E+7nMAssay Description:Inhibition of peripheral benzodiazepine BZD receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed