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Found 418 with Last Name = 'denny' and Initial = 'ra'
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302220(7-((1-((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]citalopram from human serotonin transporter expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302225((1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]citalopram from human serotonin transporter expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302213((3S)-3-(((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-...)
Affinity DataKi:  2nMAssay Description:Agonist activity at 5-HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302213((3S)-3-(((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-...)
Affinity DataKi:  2nMAssay Description:Agonist activity at 5-HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302213((3S)-3-(((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]spiperone from D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302213((3S)-3-(((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]spiperone from D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]spiperone from D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302218(7-(1-((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-y...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]citalopram from human serotonin transporter expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302212((3S)-3-((3-( 6-fluoro-2,3,4,9-tetrahydro-1H-carbaz...)
Affinity DataKi:  6nMAssay Description:Agonist activity at 5-HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302213((3S)-3-(((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-...)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]citalopram from human serotonin transporter expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302213((3S)-3-(((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-...)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]citalopram from human serotonin transporter expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302224(7-((1R,4R)-5-((6-fluoro-2,3,4,9-tetrahydro-1H-carb...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]citalopram from human serotonin transporter expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302221(7-((1-(2-(6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]citalopram from human serotonin transporter expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50378462(CHEMBL1237149)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]spiperone from D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302224(7-((1R,4R)-5-((6-fluoro-2,3,4,9-tetrahydro-1H-carb...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]spiperone from D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302212((3S)-3-((3-( 6-fluoro-2,3,4,9-tetrahydro-1H-carbaz...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]citalopram from human serotonin transporter expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302212((3S)-3-((3-( 6-fluoro-2,3,4,9-tetrahydro-1H-carbaz...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]citalopram from human serotonin transporter expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302223(4-(4-((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-y...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]spiperone from D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302214((3S)-3-((2-(6-fluoro-2,3,4,9-tetrahydro-1H-carbazo...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]citalopram from human serotonin transporter expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302214((3S)-3-((2-(6-fluoro-2,3,4,9-tetrahydro-1H-carbazo...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]citalopram from human serotonin transporter expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302214((3S)-3-((2-(6-fluoro-2,3,4,9-tetrahydro-1H-carbazo...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]spiperone from D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302214((3S)-3-((2-(6-fluoro-2,3,4,9-tetrahydro-1H-carbazo...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]spiperone from D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302210((3S)-3-(((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]citalopram from human serotonin transporter expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302220(7-((1-((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]spiperone from D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302217(7-(4-((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-y...)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]citalopram from human serotonin transporter expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302217(7-(4-((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-y...)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]citalopram from human serotonin transporter expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302211((3S)-3-((2-(6-fluoro-2,3,4,9-tetrahydro-1H-carbazo...)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]spiperone from D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302222(7-((4-((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-...)
Affinity DataKi:  41nMAssay Description:Displacement of [3H]citalopram from human serotonin transporter expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302216(7-(4-(3-(6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-2...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]spiperone from D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302212((3S)-3-((3-( 6-fluoro-2,3,4,9-tetrahydro-1H-carbaz...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]spiperone from D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302212((3S)-3-((3-( 6-fluoro-2,3,4,9-tetrahydro-1H-carbaz...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]spiperone from D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302217(7-(4-((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-y...)
Affinity DataKi:  60nMAssay Description:Displacement of [3H]spiperone from D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302217(7-(4-((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-y...)
Affinity DataKi:  60nMAssay Description:Displacement of [3H]spiperone from D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302215(7-(4-((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-2-y...)
Affinity DataKi:  62nMAssay Description:Displacement of [3H]citalopram from human serotonin transporter expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302216(7-(4-(3-(6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-2...)
Affinity DataKi:  62nMAssay Description:Displacement of [3H]citalopram from human serotonin transporter expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302210((3S)-3-(((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]spiperone from D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302220(7-((1-((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-...)
Affinity DataKi:  110nMAssay Description:Binding affinity to 5-HT2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302222(7-((4-((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-...)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]spiperone from D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302213((3S)-3-(((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-...)
Affinity DataKi:  130nMAssay Description:Binding affinity to 5-HT2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302217(7-(4-((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-y...)
Affinity DataKi:  130nMAssay Description:Agonist activity at 5-HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302213((3S)-3-(((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-...)
Affinity DataKi:  130nMAssay Description:Binding affinity to 5-HT2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302218(7-(1-((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-y...)
Affinity DataKi:  140nMAssay Description:Displacement of [3H]spiperone from D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302224(7-((1R,4R)-5-((6-fluoro-2,3,4,9-tetrahydro-1H-carb...)
Affinity DataKi:  165nMAssay Description:Binding affinity to 5-HT2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302215(7-(4-((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-2-y...)
Affinity DataKi:  220nMAssay Description:Displacement of [3H]spiperone from D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302219(7-(1-(2-(6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-3...)
Affinity DataKi:  310nMAssay Description:Displacement of [3H]spiperone from D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50378462(CHEMBL1237149)
Affinity DataKi:  460nMAssay Description:Displacement of [3H]citalopram from human serotonin transporter expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302212((3S)-3-((3-( 6-fluoro-2,3,4,9-tetrahydro-1H-carbaz...)
Affinity DataKi:  610nMAssay Description:Binding affinity to 5-HT2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302212((3S)-3-((3-( 6-fluoro-2,3,4,9-tetrahydro-1H-carbaz...)
Affinity DataKi:  610nMAssay Description:Binding affinity to 5-HT2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302217(7-(4-((6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-y...)
Affinity DataKi:  680nMAssay Description:Binding affinity to 5-HT2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302221(7-((1-(2-(6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-...)
Affinity DataKi:  720nMAssay Description:Displacement of [3H]spiperone from D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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