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Found 522 with Last Name = 'diels' and Initial = 'g'
LigandPNGBDBM50110039(1-[2-(3-Cyclopropylmethoxy-4-methoxy-phenyl)-propy...)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]rolipram from rat forebrain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)
Affinity DataKi:  11nMAssay Description:Inhibition of [3H]rolipram binding to Phosphodiesterase 4 of rat forebrain membraneMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50163631(1-Methyl-4-piperidin-4-ylidene-1,4-dihydro-1,5,7a-...)
Affinity DataKi:  12nMAssay Description:Binding affinity for H1 histamine receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50163629(CHEMBL539843 | spiro[6,11-dihydro-5H-benzo[d]imida...)
Affinity DataKi:  19nMAssay Description:Binding affinity for H1 histamine receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50163630(1-Methyl-4-piperidin-4-ylidene-1,4,8,9-tetrahydro-...)
Affinity DataKi:  22nMAssay Description:Binding affinity for H1 histamine receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)
Affinity DataKi:  26nMAssay Description:Inhibition of [3H]rolipram binding to Phosphodiesterase 4 of rat forebrain membraneMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM22876(CHEMBL998 | Claritin | Loratadine | Sch 29851 | US...)
Affinity DataKi:  37nMAssay Description:Binding affinity for H1 histamine receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistamine H1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM22890(2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-...)
Affinity DataKi:  50nMAssay Description:Binding affinity for H1 histamine receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

LigandPNGBDBM50451480(CHEMBL2093042)
Affinity DataKi:  63nMAssay Description:Displacement of [3H]rolipram from rat forebrain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50110030(1-{2-[3-(Indan-2-yloxy)-4-methoxy-phenyl]-propyl}-...)
Affinity DataKi:  180nMAssay Description:Displacement of [3H]rolipram from rat forebrain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50366802(CHEMBL1788264)
Affinity DataKi:  220nMAssay Description:Displacement of [3H]rolipram from rat forebrain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)
Affinity DataIC50:  0.200nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487969(4-(4-((5-chloro-6-(2H-1,2,3- triazol-2-yl)pyridin-...)
Affinity DataIC50:  7nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487728(N-(5-cyano-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl)...)
Affinity DataIC50:  8nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487612(1-(benzofuran-4-yl)-N-(5-chloro- 6-(2H-1,2,3-triaz...)
Affinity DataIC50:  9nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM488005((R)-N-(5-chloro-6-(2H-1,2,3- triazol-2-yl)pyridin-...)
Affinity DataIC50:  9nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487933(US10954214, Compound 355 | methyl 3-chloro-5-(1-(1...)
Affinity DataIC50:  10nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487998(N-(5-chloro-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl...)
Affinity DataIC50:  10nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL
LigandPNGBDBM50219313(CHEMBL157812)
Affinity DataIC50: <10nMAssay Description:Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487689(1-(1-amino-8-fluoroisoquinolin- 4-yl)-N-(5-cyano-6...)
Affinity DataIC50:  10nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487687(2-(3-chloro-5-(1-(quinolin-5-yl)- 5-(trifluorometh...)
Affinity DataIC50:  10nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM488028(N-(5-chloro-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl...)
Affinity DataIC50:  10nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487692(1-(benzo[d]thiazol-7-yl)-N-(5- cyano-6-(2H-1,2,3-t...)
Affinity DataIC50:  11nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487691(N-(5-cyano-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl)...)
Affinity DataIC50:  11nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM488006(N-(5-cyano-6-methoxypyridin-3- yl)-1-(1-oxo-1,2- d...)
Affinity DataIC50:  11nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487677(N-(5-cyano-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl)...)
Affinity DataIC50:  11nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487625(N-(5-cyano-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl)...)
Affinity DataIC50:  11nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM488000(N-(5-chloro-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl...)
Affinity DataIC50:  11nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487693(N-(5-chloro-6-(4- (hydroxymethyl)-2H-1,2,3- triazo...)
Affinity DataIC50:  12nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487581(N-(5-chloro-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl...)
Affinity DataIC50:  12nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487971(4-(4-((5-chloro-2-methyl-6-(2H- 1,2,3-triazol-2-yl...)
Affinity DataIC50:  12nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487731(1-(benzo[d]thiazol-7-yl)-N-(5- chloro-6-(2H-1,2,3-...)
Affinity DataIC50:  12nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487703(N-(5-chloro-6-(4-methyl-2H- 1,2,3-triazol-2-yl)pyr...)
Affinity DataIC50:  13nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487701(N-(5-chloro-2-methyl-6-(2H- 1,2,3-triazol-2-yl)pyr...)
Affinity DataIC50:  13nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487697(1-(benzo[d][1,2,3]thiadiazol-7- yl)-N-(5-cyano-6-(...)
Affinity DataIC50:  13nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487700(N-(5-cyano-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl)...)
Affinity DataIC50:  13nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487695(N-(5-chloro-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl...)
Affinity DataIC50:  13nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM488004(N-(5-chloro-2-methyl-6-(2H- 1,2,3-triazol-2-yl)pyr...)
Affinity DataIC50:  13nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM488008(N-(5-chloro-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl...)
Affinity DataIC50:  13nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM488021((*S)-N-(5-chloro-6-(2H-1,2,3- triazol-2-yl)pyridin...)
Affinity DataIC50:  13nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487587(N-(5-chloro-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl...)
Affinity DataIC50:  13nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487696(N-(5-cyano-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl)...)
Affinity DataIC50:  15nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487704(N-(5-cyano-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl)...)
Affinity DataIC50:  15nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487775(N-(5-chloro-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl...)
Affinity DataIC50:  15nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487705(N-(5-chloro-6-(oxazol-2- yl)pyridin-3-yl)-1-(1-oxo...)
Affinity DataIC50:  15nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487669(N-(5-chloro-6-(oxazol-2- yl)pyridin-3-yl)-1-(quino...)
Affinity DataIC50:  15nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487694(N-(5-chloro-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl...)
Affinity DataIC50:  15nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487997(N-(5-chloro-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl...)
Affinity DataIC50:  15nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487706(N-(5-cyano-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl)...)
Affinity DataIC50:  16nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMucosa-associated lymphoid tissue lymphoma translocation protein 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM487707(N-(3-chloro-4-(2H-1,2,3-triazol- 2-yl)phenyl)-1-(1...)
Affinity DataIC50:  16nMAssay Description:MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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