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Found 712 with Last Name = 'dunn' and Initial = 'd'
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36608(Rapamycin C-7, analog 1)
Affinity DataKi:  0.600nM EC50:  1nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36613(Rapamycin C-7, analog 6b)
Affinity DataKi:  1nM EC50:  4nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36623(Rapamycin C-7, analog 12)
Affinity DataKi:  1nM EC50:  2nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36627(Rapamycin C-7, analog 16a)
Affinity DataKi:  1nM EC50:  45nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36609(Rapamycin C-7, analog 4 | SIROLIMUS | US11603377, ...)
Affinity DataKi:  1nM EC50:  30nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36612(Rapamycin C-7, analog 6a)
Affinity DataKi:  1nM EC50:  4nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353165(CHEMBL1829472)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]NAMH from human cloned histamine 3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50350022(CHEMBL1813057)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]NAMH from human cloned histamine 3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36622(Rapamycin C-7, analog 11b)
Affinity DataKi:  1.5nM EC50:  70nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361051(CHEMBL1935590)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]LSD from full length human 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50360899(CHEMBL1935110)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065404((R)-N-((S)-5-Benzenesulfonylamino-1-formyl-pentyl)...)
Affinity DataKi:  2nMAssay Description:Inhibitory activity against recombinant human Calpain-I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50360897(CHEMBL1935108)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50350021(CHEMBL1813067)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]NAMH from human cloned histamine 3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361055(CHEMBL1935599)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]LSD from full length human 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353181(CHEMBL1829485)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]NAMH from human cloned histamine 3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50350030(CHEMBL1813060)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]NAMH from human cloned histamine 3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50012572(CHEMBL3260795)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]LSD from human recombinant 5-HT6 receptor expressed in CHO-K1 cell membrane after 3 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361052(CHEMBL1935589 | CHEMBL1949758)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]LSD from full length human 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353167(CHEMBL1829475)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353167(CHEMBL1829475)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]NAMH from human cloned histamine 3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361058(CHEMBL1935594)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]LSD from full length human 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353164(CHEMBL1829469)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]NAMH from human cloned histamine 3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36619(Rapamycin C-7, analog 10a)
Affinity DataKi:  3nM EC50:  20nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353163(CHEMBL1829474)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]NAMH from human cloned histamine 3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50360889(CHEMBL1935100)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353166(CHEMBL1829473)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]NAMH from human cloned histamine 3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353168(CHEMBL1829337)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]NAMH from human cloned histamine 3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36610(Rapamycin C-7, analog 5a)
Affinity DataKi:  3.5nM EC50:  10nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36615(Rapamycin C-7, analog 7b)
Affinity DataKi:  3.70nM EC50:  2.50E+3nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065398((R)-3-Benzyloxy-N-[(S)-1-(4-benzyloxy-benzyl)-2-ox...)
Affinity DataKi:  4nMAssay Description:Inhibitory activity against recombinant human Calpain-I receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065404((R)-N-((S)-5-Benzenesulfonylamino-1-formyl-pentyl)...)
Affinity DataKi:  4nMAssay Description:Inhibitory activity against cathepsin B receptor in human liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50360899(CHEMBL1935110)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36611(Rapamycin C-7, analog 5b)
Affinity DataKi:  4nM EC50:  200nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50360902(CHEMBL1935114)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353169(CHEMBL1829479)
Affinity DataKi:  4.40nMAssay Description:Displacement of [3H]NAMH from human cloned histamine 3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361053(CHEMBL1935601)
Affinity DataKi:  4.40nMAssay Description:Displacement of [3H]LSD from full length human 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36614(Rapamycin C-7, analog 7a)
Affinity DataKi:  4.5nM EC50: >1.00E+4nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353181(CHEMBL1829485)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]NAMH from rat cloned histamine 3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

LigandPNGBDBM36625(Rapamycin C-7, analog 14a)
Affinity DataKi:  5nM EC50:  6nMAssay Description:FKBP12 assay using rapamycin analogs.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065398((R)-3-Benzyloxy-N-[(S)-1-(4-benzyloxy-benzyl)-2-ox...)
Affinity DataKi:  5nMAssay Description:Inhibitory activity against Calpain-II receptor in porcine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-2 catalytic subunit(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50065407((R)-N-((S)-1-Benzyl-2-oxo-ethyl)-3-benzyloxy-2-met...)
Affinity DataKi:  5nMAssay Description:Inhibitory activity against Calpain-II receptor in porcine kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50360894(CHEMBL1935105)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50360892(CHEMBL1935103)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50365043(CHEMBL1951055)
Affinity DataKi:  5.40nMAssay Description:Displacement of [3H]NAMH from human histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50360888(CHEMBL1935111)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361050(CHEMBL1935592)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]LSD from full length human 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50360888(CHEMBL1935111)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353170(CHEMBL1829468)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]NAMH from human cloned histamine 3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353172(CHEMBL1829477)
Affinity DataKi:  5.80nMAssay Description:Displacement of [3H]NAMH from human cloned histamine 3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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