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Found 122 with Last Name = 'dutruc-rosset' and Initial = 'g'
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283917(1-(1,1-Diphenyl-silolan-3-yl)-4-(4-fluoro-phenyl)-...)
Affinity DataIC50:  0.900nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283931(1-(1,1-Diphenyl-silolan-3-yl)-4-phenyl-piperazine ...)
Affinity DataIC50:  1nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50001775((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)
Affinity DataIC50:  1.70nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283920(1-[1,1-Bis-(4-fluoro-phenyl)-silolan-3-yl]-4-pheny...)
Affinity DataIC50:  2nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283920(1-[1,1-Bis-(4-fluoro-phenyl)-silolan-3-yl]-4-pheny...)
Affinity DataIC50:  3nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283928(1-(1,1-Diphenyl-silolan-3-yl)-4-(3-fluoro-phenyl)-...)
Affinity DataIC50:  3.40nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313678(CHEMBL1093747 | N-(5-bromo-6-(4-hydroxyphenyl)-1H-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313696(CHEMBL1086427 | N-(6-chloro-7-fluoro-5-phenyl-1H-i...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313661(CHEMBL1095040 | N-(6-chloro-5-phenyl-1H-indazol-3-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313662(CHEMBL1095041 | N-(5-(4-aminophenyl)-6-chloro-1H-i...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313663(CHEMBL1095366 | N-(6-chloro-5-(4-hydroxyphenyl)-1H...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283929(1-(1,1-Diphenyl-silolan-3-yl)-4-p-tolyl-piperazine...)
Affinity DataIC50:  10nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313664(CHEMBL1077218 | N-(6-chloro-5-(furan-3-yl)-1H-inda...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313697(CHEMBL1097003 | N-(6,7-dichloro-5-phenyl-1H-indazo...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313665(CHEMBL1077213 | N-(6-chloro-5-(4-ethylphenyl)-1H-i...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313670(CHEMBL1089723 | N-(5-(furan-2-yl)-6-(4-hydroxyphen...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313666(CHEMBL1097694 | N-(6-chloro-5-p-tolyl-1H-indazol-3...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283921(1-(1,1-Diphenyl-silolan-3-yl)-4-(4-fluoro-phenyl)-...)
Affinity DataIC50:  14nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313667(CHEMBL1091081 | N-(6-chloro-5-(4-nitrophenyl)-1H-i...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283919(1-[1,1-Bis-(4-fluoro-phenyl)-silolan-3-yl]-4-(4-fl...)
Affinity DataIC50:  18nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313668(CHEMBL1091082 | N-(6-chloro-5-(4-fluorophenyl)-1H-...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313669(CHEMBL1091083 | N-(5-(4-(benzyloxy)phenyl)-6-chlor...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283924(1-(4-Chloro-phenyl)-4-(1,1-diphenyl-silolan-3-yl)-...)
Affinity DataIC50:  25nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313703(CHEMBL1082236 | N-(6-(3,4-dihydroxyphenyl)-1H-inda...)
Affinity DataIC50:  27nMAssay Description:Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283918(1-[1-(4-Fluoro-phenyl)-1-phenyl-silolan-3-yl]-4-ph...)
Affinity DataIC50:  27nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283918(1-[1-(4-Fluoro-phenyl)-1-phenyl-silolan-3-yl]-4-ph...)
Affinity DataIC50:  27nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283923(1-(1,1-Diphenyl-silolan-3-yl)-4-pyridin-2-yl-piper...)
Affinity DataIC50:  29nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313664(CHEMBL1077218 | N-(6-chloro-5-(furan-3-yl)-1H-inda...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant GSK3beta by kinetic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283926(1-(1,1-Diphenyl-silolan-3-yl)-4-m-tolyl-piperazine...)
Affinity DataIC50:  33nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313698(CHEMBL1082237 | N-(6-(4-hydroxyphenyl)-1H-indazol-...)
Affinity DataIC50:  44nMAssay Description:Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283925(4-[4-(1,1-Diphenyl-silolan-3-yl)-piperazin-1-yl]-p...)
Affinity DataIC50:  46nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313672(CHEMBL1093079 | N-(5-(4-ethylphenyl)-6-(4-hydroxyp...)
Affinity DataIC50:  49nMAssay Description:Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313699(CHEMBL1077233 | N-(6-chloro-5-(pyridin-4-yl)-1H-in...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283927(1-(1,1-Diphenyl-silolan-3-yl)-4-phenyl-piperidine ...)
Affinity DataIC50:  53nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313700(CHEMBL1089722 | N-(5-bromo-6-chloro-1H-indazol-3-y...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313676(CHEMBL1093745 | N-(6-(4-hydroxyphenyl)-5-phenyl-1H...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313704(CHEMBL1088618 | N-(6-(2-chloro-4-hydroxyphenyl)-1H...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313674(CHEMBL1093390 | N-(5,6-bis(4-hydroxyphenyl)-1H-ind...)
Affinity DataIC50:  56nMAssay Description:Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313678(CHEMBL1093747 | N-(5-bromo-6-(4-hydroxyphenyl)-1H-...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human recombinant GSK3beta by kinetic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313705(CHEMBL1086638 | N-(6-(4-aminophenyl)-1H-indazol-3-...)
Affinity DataIC50:  76nMAssay Description:Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283930(2-[4-(1,1-Diphenyl-silolan-3-yl)-piperazin-1-yl]-p...)
Affinity DataIC50:  80nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313661(CHEMBL1095040 | N-(6-chloro-5-phenyl-1H-indazol-3-...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human recombinant GSK3beta by kinetic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313663(CHEMBL1095366 | N-(6-chloro-5-(4-hydroxyphenyl)-1H...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human recombinant GSK3beta by kinetic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313706(CHEMBL1086639 | N-(6-(3-hydroxyphenyl)-1H-indazol-...)
Affinity DataIC50:  94nMAssay Description:Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313673(CHEMBL1077243 | N-(5-(furan-3-yl)-6-(4-hydroxyphen...)
Affinity DataIC50:  98nMAssay Description:Inhibition of human recombinant GSK3-beta using gamma[33P]-ATP after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283920(1-[1,1-Bis-(4-fluoro-phenyl)-silolan-3-yl]-4-pheny...)
Affinity DataIC50:  100nMAssay Description:Binding affinity towards dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(2) dopamine receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283920(1-[1,1-Bis-(4-fluoro-phenyl)-silolan-3-yl]-4-pheny...)
Affinity DataIC50:  100nMAssay Description:Binding affinity towards dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313661(CHEMBL1095040 | N-(6-chloro-5-phenyl-1H-indazol-3-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Cdk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50283932(1-(1,1-Diphenyl-silolan-3-yl)-4-(2-fluoro-phenyl)-...)
Affinity DataIC50:  100nMAssay Description:In vitro binding affinity towards serotonin 5-HT2A receptor in rat cortical membranes using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Sanofi-Aventis

Curated by ChEMBL
LigandPNGBDBM50313668(CHEMBL1091082 | N-(6-chloro-5-(4-fluorophenyl)-1H-...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human recombinant GSK3beta by kinetic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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