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Found 736 with Last Name = 'emami' and Initial = 's'
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50052204(CHEMBL3318392)
Affinity DataKi:  1.10nMAssay Description:Mixed type inhibition of electric eel AChE using acetylthiocholine iodide substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataKi:  4.20nMAssay Description:Inhibition of electric eel AChE pre-incubated for 3 mins before acetylthiocholine substrate addition by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Mazandaran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM82353(1-{3-[4-(substitutedphenyl)piperazin1-yl]propyl}-1...)
Affinity DataKi:  9.90nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma-2 receptor in rat liver membranes after 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50457028(CHEMBL4218303)
Affinity DataKi:  13nMAssay Description:Mixed-type inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Mazandaran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM82351(1-{[4-(substitutedphenyl/phenylethyl)piperazin1-yl...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes after 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Mazandaran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50595018(CHEMBL5208027)
Affinity DataKi:  29nMAssay Description:Binding affinity to BuChE (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Mazandaran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50569812(CHEMBL4869068)
Affinity DataKi:  40nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-DOPA as substrate by Lineweaver-Burk double reciprocal plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50235419(CHEMBL4077932)
Affinity DataKi:  49nMAssay Description:Mixed-type inhibition of electric eel AChE preincubated for 5 mins followed by varying levels acetylthiocholine iodide substrate addition by Lineweav...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Mazandaran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM82351(1-{[4-(substitutedphenyl/phenylethyl)piperazin1-yl...)
Affinity DataKi:  56nMAssay Description:Displacement of [3H]-di-o-tolylguanidine from sigma-2 receptor in rat liver membranes after 180 mins by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Mazandaran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50569806(CHEMBL4865646)
Affinity DataKi:  70nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-DOPA as substrate by Lineweaver-Burk double reciprocal plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Mazandaran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50569801(CHEMBL4867662)
Affinity DataKi:  90nMAssay Description:Competitive inhibition of mushroom tyrosinase using L-DOPA as substrate by Lineweaver-Burk double reciprocal plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50080392(CHEMBL3416513)
Affinity DataKi:  270nMAssay Description:Inhibition of electric eel AChE pre-incubated for 3 mins before acetylthiocholine substrate addition by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50204859(CHEMBL3939483)
Affinity DataKi:  490nMAssay Description:Mixed type inhibition of electric eel AChE using acetylthiocholine iodide as substrate incubated for 5 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50197934(CHEMBL3889532)
Affinity DataKi:  490nMAssay Description:Mixed-type inhibition of electric eel AChE using acetylthiocholine iodide as substrate measured for 2 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50038390(CHEMBL3352904)
Affinity DataKi:  490nMAssay Description:Inhibition of electric eel AChE by Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50020730(CHEMBL1469070)
Affinity DataKi:  1.32E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine as substrate by Lineweavere-Burk plotMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Mazandaran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50595017(CHEMBL3606084)
Affinity DataKi:  3.50E+3nMAssay Description:Binding affinity to autotaxin (unknown origin) phosphodiesterase activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50406864(CHEMBL4161244)
Affinity DataKi:  6.91E+3nMAssay Description:Non-competitive inhibition of electric eel AChE using varying levels of acetylthiocholine iodide as substrate pretreated for 5 mins followed by subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
University Of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
University Of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50434353(CHEMBL2386747 | US9446044, 72)
Affinity DataIC50:  0.280nMAssay Description:Inhibition of DYRK1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50443517(CHEMBL3087899)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of electric eel AChE using acetylcholine as substrate preincubated for 15 mins prior to substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
University Of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50:  0.360nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50052204(CHEMBL3318392)
Affinity DataIC50:  0.440nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide substrate by Ellman method based spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
University Of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM246383(US9446044, 69)
Affinity DataIC50:  0.590nMAssay Description:Inhibition of DYRK1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
University Of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50434352(CHEMBL2386748 | US9446044, 78)
Affinity DataIC50:  0.940nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
University Of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50434364(CHEMBL2386764 | US9446044, 65)
Affinity DataIC50:  0.980nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
University Of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM246384(US9446044, 71)
Affinity DataIC50:  0.990nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
University Of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50434352(CHEMBL2386748 | US9446044, 78)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of DYRK1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50052206(CHEMBL3318391)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide substrate by Ellman method based spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50052208(CHEMBL3318394)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide substrate by Ellman method based spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
University Of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM246384(US9446044, 71)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of DYRK1B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50443513(CHEMBL3087903)
Affinity DataIC50:  2nMAssay Description:Inhibition of electric eel AChE using acetylcholine as substrate preincubated for 15 mins prior to substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50443518(CHEMBL3087898)
Affinity DataIC50:  2nMAssay Description:Inhibition of electric eel AChE using acetylcholine as substrate preincubated for 15 mins prior to substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50097456(CHEMBL3585822)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
University Of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50434364(CHEMBL2386764 | US9446044, 65)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of DYRK1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50052210(CHEMBL3318398)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide substrate by Ellman method based spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50073207(CHEMBL3408398)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine substrate by Ellman's reagent based methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50052212(CHEMBL3318400)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide substrate by Ellman method based spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50073217(CHEMBL3408242)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine substrate by Ellman's reagent based methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Mazandaran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50204847(CHEMBL3895802)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate incubated for 5 mins followed by substrate addition measured for 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50443515(CHEMBL3087901)
Affinity DataIC50:  5nMAssay Description:Inhibition of electric eel AChE using acetylcholine as substrate preincubated for 15 mins prior to substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50052214(CHEMBL3318402)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide substrate by Ellman method based spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50594712(CHEMBL5181664)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of electric eel AChEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50073208(CHEMBL3408397)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine substrate by Ellman's reagent based methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Mazandaran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50204842(CHEMBL3927698)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate incubated for 5 mins followed by substrate addition measured for 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50052215(CHEMBL3318403)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide substrate by Ellman method based spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50594714(CHEMBL5208725)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of equine serum BuChEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50073220(CHEMBL3408241)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine substrate by Ellman's reagent based methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Yazd University

Curated by ChEMBL
LigandPNGBDBM50594711(CHEMBL5208529)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of electric eel AChEMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCholinesterase(Homo sapiens (Human))
Mazandaran University Of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50204851(CHEMBL3947445)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant BChE using butyrylthiocholine iodide as substrate incubated for 5 mins followed by substrate addition measured for 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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