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Found 16 with Last Name = 'fernández' and Initial = 'jl'
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Laboratories Del Dr. Esteve

US Patent
LigandPNGBDBM317225(6-(Azepan-1- ylmethyl)-2- phenylimidazo[2,1- b]thi...)
Affinity DataKi:  16nMAssay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Laboratories Del Dr. Esteve

US Patent
LigandPNGBDBM317227(6-((2-(Azepan-1- ylethoxy)methyl)-2- phenylimidazo...)
Affinity DataKi:  40nMAssay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Laboratories Del Dr. Esteve

US Patent
LigandPNGBDBM317226(6-((4- Methylpiperazin-1- ylmethyl)-2- phenylimida...)
Affinity DataKi:  56nMAssay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Laboratories Del Dr. Esteve

US Patent
LigandPNGBDBM317230(2-(Azepan-1- ylmethyl)-6- phenylimidazo[2,1- b]thi...)
Affinity DataKi:  100nMAssay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Laboratories Del Dr. Esteve

US Patent
LigandPNGBDBM317218(US9617281, Compound 4)
Affinity DataKi:  168nMAssay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Laboratories Del Dr. Esteve

US Patent
LigandPNGBDBM317228(2-Phenyl-6-((2- (pyrrolidin-1- yl)ethoxy)methyl) i...)
Affinity DataKi:  190nMAssay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Laboratories Del Dr. Esteve

US Patent
LigandPNGBDBM317231(2-(4-Fluorophenyl)- 6-((4- methylpiperazin-1- yl)m...)
Affinity DataKi:  210nMAssay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Laboratories Del Dr. Esteve

US Patent
LigandPNGBDBM317229(6-((4- Methylpiperazin-1- ylmethyl)-2- phenylimida...)
Affinity DataKi:  260nMAssay Description:Brain membrane preparation and binding assays for the σ1-receptor were performed as described (DeHaven-Hudkins, D. L., L. C. Fleissner, and F. Y...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTubulin beta-2B chain(Bos taurus)
Universidad De Salamanca

Curated by ChEMBL
LigandPNGBDBM50159568(1-Methyl-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibitory concentration value against bovine brain tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Universidad De Salamanca

Curated by ChEMBL
LigandPNGBDBM50159538(2-Methoxy-5-((Z)-2-naphthalen-2-yl-vinyl)-phenol |...)
Affinity DataIC50:  3.00E+3nMAssay Description:In vitro inhibitory concentration value against bovine brain tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Universidad De Salamanca

Curated by ChEMBL
LigandPNGBDBM50159552(9-Methyl-3-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]...)
Affinity DataIC50:  6.00E+3nMAssay Description:In vitro inhibitory concentration value against bovine brain tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Universidad De Salamanca

Curated by ChEMBL
LigandPNGBDBM50159583(2-[(Z)-2-(3,4,5-Trimethoxy-phenyl)-vinyl]-naphthal...)
Affinity DataIC50:  1.00E+4nMAssay Description:In vitro inhibitory concentration value against bovine brain tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Universidad De Salamanca

Curated by ChEMBL
LigandPNGBDBM50159534(2-[(Z)-2-(3,4-Dimethoxy-5-nitro-phenyl)-vinyl]-nap...)
Affinity DataIC50:  1.30E+4nMAssay Description:In vitro inhibitory concentration value against bovine brain tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Universidad De Salamanca

Curated by ChEMBL
LigandPNGBDBM50159562(2-Methoxy-5-[(Z)-2-(4-methoxy-naphthalen-2-yl)-vin...)
Affinity DataIC50:  1.60E+4nMAssay Description:In vitro inhibitory concentration value against bovine brain tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Universidad De Salamanca

Curated by ChEMBL
LigandPNGBDBM50159543(5-[(Z)-2-(3,4,5-Trimethoxy-phenyl)-vinyl]-1H-indol...)
Affinity DataIC50:  2.50E+4nMAssay Description:In vitro inhibitory concentration value against bovine brain tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Universidad De Salamanca

Curated by ChEMBL
LigandPNGBDBM50159557(1-Methyl-5-[(E)-2-(3,4,5-trimethoxy-phenyl)-vinyl]...)
Affinity DataIC50:  3.00E+4nMAssay Description:In vitro inhibitory concentration value against bovine brain tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed