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Found 835 with Last Name = 'ferraris' and Initial = 'd'
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Eisai Research Institute

Curated by ChEMBL
LigandPNGBDBM50246899((S)-2-(3-((S)-1-carboxy-5-(4-iodobenzamido)pentyl)...)
Affinity DataKi:  0.0100nMAssay Description:Inhibition of GCP2 by top scintillation counter in presence of 30 nM NAA[3]GMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Johns Hopkins University Brain Science Institute

Curated by ChEMBL
LigandPNGBDBM50322367(5-(4-(pyrrolidin-1-ylmethyl)phenyl)-2,3,4,6-tetrah...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Johns Hopkins University Brain Science Institute

Curated by ChEMBL
LigandPNGBDBM50154730(6-(4-((dimethylamino)methyl)phenyl)-3,4-dihydro-[1...)
Affinity DataKi:  6.40nMAssay Description:Inhibition of PARP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50117763(CHEMBL3613921 | US9505753, 5u)
Affinity DataKi:  60nMAssay Description:Competitive inhibition of recombinant human DAAO expressed in HEK cells by double reciprocal plot analysis in presence of D-serineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50538688(CHEMBL4642789)
Affinity DataKi:  120nMAssay Description:Competitive inhibition of human recombinant ALDH1A3 pre-incubated for 5 mins before acetaldehyde addition by continuous spectrometric assay relative ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50527781(CHEMBL4456676)
Affinity DataKi:  540nMAssay Description:Competitive inhibition of recombinant human 6His-tagged ALDH1A3 expressed in Escherichia coli BL21(DE3) using varying level of acetaldehyde as substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetRetinal dehydrogenase 2(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM50538688(CHEMBL4642789)
Affinity DataKi:  920nMAssay Description:Competitive inhibition of human recombinant ALDH1A2 pre-incubated for 5 mins before acetaldehyde addition by continuous spectrometric assay relative ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456068(CHEMBL4208344)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis IMPDH2 Y487C mutant using IMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456074(CHEMBL4202438)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM108460(CHEMBL2178393 | US11191732, Example 1 | US8604016,...)
Affinity DataKi:  2.00E+3nMAssay Description:Uncompetitive inhibition of human kidney glutaminase (124 to 669) assessed as reduction of glutamine hydrolysis by double-reciprocal plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456086(CHEMBL4204706)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456092(CHEMBL4218122)
Affinity DataKi:  2.90E+3nMAssay Description:Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456097(CHEMBL4217858)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGMP reductase 2(Homo sapiens)
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456098(CHEMBL4214376)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human GMPR2 using GMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGMP reductase 2(Homo sapiens)
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456089(CHEMBL4205578)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human GMPR2 using GMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGMP reductase 2(Homo sapiens)
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456082(CHEMBL4211507)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human GMPR2 using GMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGMP reductase 2(Homo sapiens)
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456099(CHEMBL4215689)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human GMPR2 using GMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGMP reductase 2(Homo sapiens)
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456090(CHEMBL4210733)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human GMPR2 using GMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGMP reductase 2(Homo sapiens)
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456091(CHEMBL4218662)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human GMPR2 using GMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456067(CHEMBL4203696)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456079(CHEMBL4209344)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGMP reductase 2(Homo sapiens)
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456100(CHEMBL4209101)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human GMPR2 using GMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGMP reductase 2(Homo sapiens)
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456101(CHEMBL4213736)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human GMPR2 using GMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGMP reductase 2(Homo sapiens)
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456083(CHEMBL4213733)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human GMPR2 using GMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGMP reductase 2(Homo sapiens)
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456093(CHEMBL4213588)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human GMPR2 using GMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGMP reductase 2(Homo sapiens)
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456102(CHEMBL4207404)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human GMPR2 using GMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456100(CHEMBL4209101)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456098(CHEMBL4214376)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456103(CHEMBL4207011)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456104(CHEMBL4209137)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456105(CHEMBL4212299)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGMP reductase 2(Homo sapiens)
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50432798(CHEMBL2348814)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human GMPR2 using GMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGMP reductase 2(Homo sapiens)
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456087(CHEMBL4208384)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human GMPR2 using GMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGMP reductase 2(Homo sapiens)
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456103(CHEMBL4207011)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human GMPR2 using GMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGMP reductase 2(Homo sapiens)
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456104(CHEMBL4209137)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human GMPR2 using GMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGMP reductase 2(Homo sapiens)
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456105(CHEMBL4212299)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human GMPR2 using GMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456078(CHEMBL4207934)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGMP reductase 2(Homo sapiens)
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456097(CHEMBL4217858)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human GMPR2 using GMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50432765(CHEMBL2348794)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456106(CHEMBL4207207)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456101(CHEMBL4213736)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456099(CHEMBL4215689)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456083(CHEMBL4213733)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456070(CHEMBL4205894)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456073(CHEMBL4204321)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456075(CHEMBL4216354)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456102(CHEMBL4207404)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456081(CHEMBL4210836)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human IMPDH2 using IMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGMP reductase 2(Homo sapiens)
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50432765(CHEMBL2348794)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human GMPR2 using GMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGMP reductase 2(Homo sapiens)
National Institute Of Allergy And Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50456106(CHEMBL4207207)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human GMPR2 using GMP as substrate by spectrophotometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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