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Found 342 with Last Name = 'fillery' and Initial = 'sm'
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575300(CHEMBL4851414)
Affinity DataIC50:  3nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575300(CHEMBL4851414)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575298(CHEMBL4859723)
Affinity DataIC50:  4nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575298(CHEMBL4859723)
Affinity DataIC50:  4nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM291687(N-((5-Fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM291687(N-((5-Fluoro-2,3-dihydrobenzofuran-4-yl)methyl)-8-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575293(CHEMBL4855253)
Affinity DataIC50:  6nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575293(CHEMBL4855253)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataIC50:  7nMAssay Description:Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575302(CHEMBL4847216)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575302(CHEMBL4847216)
Affinity DataIC50:  8nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575303(CHEMBL4850478)
Affinity DataIC50:  9nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575303(CHEMBL4850478)
Affinity DataIC50:  9nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575294(CHEMBL4855124)
Affinity DataIC50:  13nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575294(CHEMBL4855124)
Affinity DataIC50:  13nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575292(CHEMBL4871456)
Affinity DataIC50:  13nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584944(CHEMBL5087319)
Affinity DataIC50:  14nMAssay Description:Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575292(CHEMBL4871456)
Affinity DataIC50:  14nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575291(CHEMBL4850269)
Affinity DataIC50:  15nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575291(CHEMBL4850269)
Affinity DataIC50:  16nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575296(CHEMBL4870866)
Affinity DataIC50:  16nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584944(CHEMBL5087319)
Affinity DataIC50:  16nMAssay Description:Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575296(CHEMBL4870866)
Affinity DataIC50:  17nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575295(CHEMBL4850017)
Affinity DataIC50:  19nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584945(CHEMBL5093862)
Affinity DataIC50:  20nMAssay Description:Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584945(CHEMBL5093862)
Affinity DataIC50:  20nMAssay Description:Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584946(CHEMBL5090369)
Affinity DataIC50:  20nMAssay Description:Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575289(CHEMBL4858670)
Affinity DataIC50:  20nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575289(CHEMBL4858670)
Affinity DataIC50:  20nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575274(CHEMBL4856933)
Affinity DataIC50:  20nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575286(CHEMBL4862641)
Affinity DataIC50:  20nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575274(CHEMBL4856933)
Affinity DataIC50:  20nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575295(CHEMBL4850017)
Affinity DataIC50:  20nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575286(CHEMBL4862641)
Affinity DataIC50:  21nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584946(CHEMBL5090369)
Affinity DataIC50:  22nMAssay Description:Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575264(CHEMBL4845735)
Affinity DataIC50:  24nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575301(CHEMBL4866431)
Affinity DataIC50:  25nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575301(CHEMBL4866431)
Affinity DataIC50:  25nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575264(CHEMBL4845735)
Affinity DataIC50:  25nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50384248(CHEMBL2030451)
Affinity DataIC50:  28nMAssay Description:Inhibition of recombinant FLAG-tagged mTOR kinase expressed in HEK293 cells using Biotin-Ahx-Lys-Lys-Ala-Asn-Gln-Val-Phe-Leu-Gly-Phe-Thr-Tyr-Val-Ala-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575279(CHEMBL4862266)
Affinity DataIC50:  29nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575279(CHEMBL4862266)
Affinity DataIC50:  32nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50584941(CHEMBL5077167)
Affinity DataIC50:  32nMAssay Description:Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50157003(CHEMBL369352 | N-Cyclopropyl-N-[1-(3,3-diphenyl-pr...)
Affinity DataIC50:  33nMAssay Description:Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50157002(1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-1-ethyl...)
Affinity DataIC50:  35nMAssay Description:Binding of [125I]-RANTES to membranes prepared from chinese hamster ovary (CHO) cells stably expressing recombinant human C-C chemokine receptor type...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575263(CHEMBL4846342)
Affinity DataIC50:  36nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575267(CHEMBL4869385)
Affinity DataIC50:  36nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575267(CHEMBL4869385)
Affinity DataIC50:  36nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolycomb protein EED(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50575263(CHEMBL4846342)
Affinity DataIC50:  36nMAssay Description:Inhibition of EED in human G-401 cells assessed as reduction in H3K27 trimethylation incubated for 48 hrs by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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