Found 67 with Last Name = 'fimognari' and Initial = 'c' TargetHistone deacetylase 1/REST corepressor 3(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Inhibition of HDAC1/CoREST3 in HEK293 whole cell extract using fluorescent acetylated histone peptide as substrate after 60 mins by fluorescence base...More data for this Ligand-Target Pair
3D Structure (crystal)TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Irreversible inhibition of recombinant human MAO-A expressed in baculovirus infected BT1 cells using p-tyramine as substrate by Lineweaver-Burk plot ...More data for this Ligand-Target Pair
TargetHistone deacetylase 1/REST corepressor 3(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Inhibition of HDAC1/CoREST3 in HEK293 whole cell extract using fluorescent acetylated histone peptide as substrate after 60 mins by fluorescence base...More data for this Ligand-Target Pair
TargetHistone deacetylase 1/REST corepressor 3(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataKi: 43nMAssay Description:Inhibition of HDAC1/CoREST3 in HEK293 whole cell extract using fluorescent acetylated histone peptide as substrate after 60 mins by fluorescence base...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 55nMAssay Description:Irreversible inhibition of recombinant human MAO-B expressed in baculovirus infected BT1 cells using benzylamine as substrate at 200 uM preincubated ...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:Competitive inhibition of recombinant human MAO-B expressed in baculovirus infected BT1 cells using benzylamine as substrate at 200 uM preincubated f...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 4.90E+3nMAssay Description:Competitive inhibition of MAOA in human SH-SY5Y cells using p-tyramine as substrate preincubated for 5 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 5.00E+3nMAssay Description:Irreversible inhibition of recombinant human MAO-A expressed in baculovirus infected BT1 cells using p-tyramine as substrate by Lineweaver-Burk plot ...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 9.00E+3nMAssay Description:Competitive inhibition of recombinant human MAO-B expressed in baculovirus infected BT1 cells using benzylamine as substrate at 200 uM preincubated f...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 1.60E+4nMAssay Description:Competitive inhibition of recombinant human MAO-A expressed in baculovirus infected BT1 cells using p-tyramine as substrate by Lineweaver-Burk plot a...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 2.30E+4nMAssay Description:Mixed type inhibition of recombinant human MAO-B expressed in baculovirus infected BT1 cells using benzylamine as substrate at 200 uM preincubated fo...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 5.50E+4nMAssay Description:Mixed type inhibition of recombinant human MAO-A expressed in baculovirus infected BT1 cells using p-tyramine as substrate by Lineweaver-Burk plot an...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 1.29E+5nMAssay Description:Mixed type inhibition of recombinant human MAO-B expressed in baculovirus infected BT1 cells using benzylamine as substrate at 200 uM preincubated fo...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 1.70E+5nMAssay Description:Mixed type inhibition of recombinant human MAO-A expressed in baculovirus infected BT1 cells using p-tyramine as substrate by Lineweaver-Burk plot an...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 1.86E+5nMAssay Description:Reversible inhibition of recombinant human MAO-A expressed in baculovirus infected BT1 cells using p-tyramine as substrate by Lineweaver-Burk plot an...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 1.88E+5nMAssay Description:Reversible inhibition of recombinant human MAO-A expressed in baculovirus infected BT1 cells using p-tyramine as substrate by Lineweaver-Burk plot an...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 2.26E+5nMAssay Description:Mixed type inhibition of recombinant human MAO-A expressed in baculovirus infected BT1 cells using p-tyramine as substrate by Lineweaver-Burk plot an...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 2.91E+5nMAssay Description:Mixed type inhibition of recombinant human MAO-B expressed in baculovirus infected BT1 cells using benzylamine as substrate at 200 uM preincubated fo...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 4.14E+5nMAssay Description:Reversible inhibition of recombinant human MAO-B expressed in baculovirus infected BT1 cells using benzylamine as substrate at 200 uM preincubated fo...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 7.85E+5nMAssay Description:Reversible inhibition of recombinant human MAO-B expressed in baculovirus infected BT1 cells using benzylamine as substrate at 200 uM preincubated fo...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 9.97E+5nMAssay Description:Reversible inhibition of recombinant human MAO-A expressed in baculovirus infected BT1 cells using p-tyramine as substrate by Lineweaver-Burk plot an...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University Of Padova
Curated by ChEMBL
University Of Padova
Curated by ChEMBL
Affinity DataKi: 1.05E+6nMAssay Description:Reversible inhibition of recombinant human MAO-B expressed in baculovirus infected BT1 cells using benzylamine as substrate at 200 uM preincubated fo...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity preincubated with NADPH regenerating system for 10 mins followed by sub...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Induction of degradation of ERalpha in human MCF7 cells at 72 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Binding affinity to human ERalpha measured after 2 hrs by fluorescence polarization plate readerMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity preincubated with NADPH regenerating system for 10 mins followed by sub...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Binding affinity to human ERalpha measured after 2 hrs by fluorescence polarization plate readerMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Induction of degradation of ERalpha in human MCF7 cells at 72 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Binding affinity to human ERalpha measured after 2 hrs by fluorescence polarization plate readerMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity preincubated with NADPH regenerating system for 10 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity preincubated with NADPH regenerating system for 10 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity preincubated with NADPH regenerating system for 10 mins followed by sub...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 76nMAssay Description:Binding affinity to human ERalpha measured after 2 hrs by fluorescence polarization plate readerMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 197nMAssay Description:Binding affinity to human ERalpha measured after 2 hrs by fluorescence polarization plate readerMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 223nMAssay Description:Induction of degradation of ERalpha in human MCF7 cells at 72 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 223nMAssay Description:Binding affinity to human ERalpha measured after 2 hrs by fluorescence polarization plate readerMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 313nMAssay Description:Binding affinity to human ERalpha measured after 2 hrs by fluorescence polarization plate readerMore data for this Ligand-Target Pair
Affinity DataIC50: 596nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity preincubated with NADPH regenerating system for 10 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataIC50: 861nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity preincubated with NADPH regenerating system for 10 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity preincubated with NADPH regenerating system for 10 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataIC50: 952nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity preincubated with NADPH regenerating system for 10 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity preincubated with NADPH regenerating system for 10 mins followed by sub...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 1.07E+3nMAssay Description:Binding affinity to human ERalpha measured after 2 hrs by fluorescence polarization plate readerMore data for this Ligand-Target Pair
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of human aromatase assessed as reduction in fluorescence intensity preincubated with NADPH regenerating system for 10 mins followed by sub...More data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human topoisomerase-2alpha-mediated relaxation of supercoiled pBR322 DNA after 1 hr by ethidium bromide staining based agarose gel elec...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 1.74E+3nMAssay Description:Binding affinity to human ERalpha measured after 2 hrs by fluorescence polarization plate readerMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 1.77E+3nMAssay Description:Binding affinity to human ERalpha measured after 2 hrs by fluorescence polarization plate readerMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Induction of degradation of ERalpha in human MCF7 cells at 72 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Binding affinity to human ERalpha measured after 2 hrs by fluorescence polarization plate readerMore data for this Ligand-Target Pair
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University Of Bologna
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human topoisomerase-2alpha-mediated relaxation of supercoiled pBR322 DNA after 1 hr by ethidium bromide staining based agarose gel elec...More data for this Ligand-Target Pair
