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Found 11 with Last Name = 'freitas' and Initial = 'ap'
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Department Of Research & Development

Curated by ChEMBL
LigandPNGBDBM50108877((3,4-Dihydroxy-5-nitro-phenyl)-p-tolyl-methanone |...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of Catechol O-methyltransferase activity in rat brainMore data for this Ligand-Target Pair
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Department Of Research & Development

Curated by ChEMBL
LigandPNGBDBM50108878(1-(3,4-Dihydroxy-5-nitro-phenyl)-2-phenyl-ethanone...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of Catechol O-methyltransferase activity in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Department Of Research & Development

Curated by ChEMBL
LigandPNGBDBM50108879((2E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-d...)
Affinity DataIC50:  12.8nMAssay Description:Inhibition of Catechol O-methyltransferase activity in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Bial

Curated by ChEMBL
LigandPNGBDBM50472303(CHEMBL314266)
Affinity DataIC50: <1.13E+5nMAssay Description:Displacement of [3H]BTX from voltage-gated sodium channel of rat cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Bial

Curated by ChEMBL
LigandPNGBDBM50240669(Acetic acid (S)-5-carbamoyl-10,11-dihydro-5H-diben...)
Affinity DataIC50: <1.38E+5nMAssay Description:Displacement of [3H]BTX from voltage-gated sodium channel of rat cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Bial

Curated by ChEMBL
LigandPNGBDBM50472302(CHEMBL315644)
Affinity DataIC50: <1.41E+5nMAssay Description:Displacement of [3H]BTX from voltage-gated sodium channel of rat cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Bial

Curated by ChEMBL
LigandPNGBDBM34179(CHEMBL1068 | MLS000084586 | OXCARBAZEPINE | SMR000...)
Affinity DataIC50: <1.61E+5nMAssay Description:Displacement of [3H]BTX from voltage-gated sodium channel of rat cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Bial

Curated by ChEMBL
LigandPNGBDBM50003659(5H-dibenzo[b,f]azepine-5-carboxamide | CARBAMAZEPI...)
Affinity DataIC50:  2.10E+5nMAssay Description:Displacement of [3H]BTX from voltage-gated sodium channel of rat cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Department Of Research & Development

Curated by ChEMBL
LigandPNGBDBM50108878(1-(3,4-Dihydroxy-5-nitro-phenyl)-2-phenyl-ethanone...)
Affinity DataIC50:  6.96E+5nMAssay Description:Inhibition of Catechol O-methyltransferase activity in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Department Of Research & Development

Curated by ChEMBL
LigandPNGBDBM50108877((3,4-Dihydroxy-5-nitro-phenyl)-p-tolyl-methanone |...)
Affinity DataIC50:  9.27E+5nMAssay Description:Inhibition of Catechol O-methyltransferase activity in rat liverMore data for this Ligand-Target Pair
TargetCatechol O-methyltransferase(Rattus norvegicus (Rat))
Department Of Research & Development

Curated by ChEMBL
LigandPNGBDBM50108879((2E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-d...)
Affinity DataIC50:  2.32E+6nMAssay Description:Inhibition of Catechol O-methyltransferase activity in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed