Affinity DataIC50: 0.177nMAssay Description:Inhibition of human MMP-9 by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 0.422nMAssay Description:Inhibition of human MMP-2 by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibitory effect of the compound against Human ET-A receptorMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Dainippon Sumitomo Pharma
Curated by ChEMBL
Dainippon Sumitomo Pharma
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Dainippon Sumitomo Pharma
Curated by ChEMBL
Dainippon Sumitomo Pharma
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Dainippon Sumitomo Pharma
Curated by ChEMBL
Dainippon Sumitomo Pharma
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory effect of the compound against porcine ET-A receptorMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:The compound was tested for binding inhibitory activity against Endothelin A receptor from porcine aortic smooth muscle membranes.More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Dainippon Sumitomo Pharma
Curated by ChEMBL
Dainippon Sumitomo Pharma
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Dainippon Sumitomo Pharma
Curated by ChEMBL
Dainippon Sumitomo Pharma
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibitory effect of the compound against Human ET-A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of histidine-tagged Pseudomonas aeruginosa LpxC (1-303) expressed in Escherichia coli BL21 (DE3) using UDP-3-O-(R-3-hydroxydecanoyl)-N-ace...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:The compound was tested for binding inhibitory activity against Endothelin A receptor from porcine aortic smooth muscle membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibitory effect of the compound against porcine ET-A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Dainippon Sumitomo Pharma
Curated by ChEMBL
Dainippon Sumitomo Pharma
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Inhibition of histidine-tagged Pseudomonas aeruginosa LpxC (1-303) expressed in Escherichia coli BL21 (DE3) using UDP-3-O-(R-3-hydroxydecanoyl)-N-ace...More data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of histidine-tagged Pseudomonas aeruginosa LpxC (1-303) expressed in Escherichia coli BL21 (DE3) using UDP-3-O-(R-3-hydroxydecanoyl)-N-ace...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Dainippon Sumitomo Pharma
Curated by ChEMBL
Dainippon Sumitomo Pharma
Curated by ChEMBL
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.70nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of histidine-tagged Pseudomonas aeruginosa LpxC (1-303) expressed in Escherichia coli BL21 (DE3) using UDP-3-O-(R-3-hydroxydecanoyl)-N-ace...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human PI3Kgamma using PtdIns/PtdSer as substrate after 2 hrs by scintillation counting analysis in presence of gamma[33P]ATPMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Dainippon Sumitomo Pharma
Curated by ChEMBL
Dainippon Sumitomo Pharma
Curated by ChEMBL
Affinity DataIC50: 7.40nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:Inhibitory effect of the compound against Human Endothelin A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Dainippon Sumitomo Pharma
Curated by ChEMBL
Dainippon Sumitomo Pharma
Curated by ChEMBL
Affinity DataIC50: 8.90nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa)
Taisho Pharmaceutical
Curated by ChEMBL
Taisho Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of histidine-tagged Pseudomonas aeruginosa LpxC (1-303) expressed in Escherichia coli BL21 (DE3) using UDP-3-O-(R-3-hydroxydecanoyl)-N-ace...More data for this Ligand-Target Pair
Affinity DataIC50: 9.30nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Dainippon Sumitomo Pharma
Curated by ChEMBL
Dainippon Sumitomo Pharma
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Dainippon Sumitomo Pharma
Curated by ChEMBL
Dainippon Sumitomo Pharma
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Dainippon Sumitomo Pharma
Curated by ChEMBL
Dainippon Sumitomo Pharma
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Dainippon Sumitomo Pharma
Curated by ChEMBL
Dainippon Sumitomo Pharma
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of rat recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:The compound was tested for binding inhibitory activity against Endothelin A receptor from porcine aortic smooth muscle membranes.More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Dainippon Sumitomo Pharma
Curated by ChEMBL
Dainippon Sumitomo Pharma
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase after 1 hr by fluorescence assayMore data for this Ligand-Target Pair